Development Level

Tchem 16 | 1,598
Tbio 12 | 11,445
Tclin 1 | 613

IMPC Phenotype

decreased circulating aspartat... 2 | 34
decreased prepulse inhibition 2 | 82
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 4
abnormal maxilla morphology 1 | 17
abnormal vibrissa morphology 1 | 25
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased lactate dehydrogenas... 1 | 16
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

ovarian cancer 24 | 8,520
Carcinoma 22 | 11,493
glioblastoma 19 | 5,792
diabetes mellitus 15 | 1,728
lung cancer 14 | 4,740
osteosarcoma 14 | 7,950
Cancer 13 | 2,499
psoriasis 13 | 6,694
subependymal giant cell astrocytoma 11 | 2,287
Breast cancer 10 | 3,578
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
Autosomal recessive predisposition 9 | 1,442
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
medulloblastoma, large-cell 9 | 6,241
tuberculosis 9 | 2,010
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
cutaneous lupus erythematosus 8 | 1,057
non-small cell lung cancer 8 | 2,890
Astrocytoma, Pilocytic 7 | 3,081
Multiple myeloma 7 | 1,332
ependymoma 7 | 4,679
gastric carcinoma 7 | 807
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
juvenile dermatomyositis 7 | 1,187
lung adenocarcinoma 7 | 2,716
primary Sjogren syndrome 7 | 735
ulcerative colitis 7 | 1,819
Arthritis 6 | 290
Chronic hepatitis C 6 | 12
Duchenne muscular dystrophy 6 | 601
Kidney cancer 6 | 2,613
acute quadriplegic myopathy 6 | 1,158
cystic fibrosis 6 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
Liver Cirrhosis, Experimental 5 | 769
breast carcinoma 5 | 1,638
Alzheimer's disease 4 | 658
Atopic dermatitis 4 | 952
Fascioliasis 4 | 17
Melanoma 4 | 711
Schizophrenia 4 | 1,160
Short stature 4 | 531
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
dermatomyositis 4 | 966
nephrosclerosis 4 | 333
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Dementia 3 | 175
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Neurodegenerative disease 3 | 414
Obesity 3 | 678
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Sensorineural Hearing Loss (disorder) 3 | 284
Stomach Neoplasms 3 | 300
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 4,104
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
mucosa-associated lymphoid tissue lymphoma 3 | 484
oligodendroglioma 3 | 2,850
pancreatic carcinoma 3 | 562
periodontitis 3 | 293
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
sonic hedgehog group medulloblastoma 3 | 467
Acquired scoliosis 2 | 281
Atrophy of cerebellum 2 | 103
Cerebellar degeneration 2 | 103
Contact Dermatitis 2 | 81
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Dermatitis, Allergic Contact 2 | 67
Dermatitis, Contact 2 | 71
Disease Progression 2 | 136
Endometriosis 2 | 540
Epilepsy 2 | 792
Heart disease 2 | 306
Infratentorial atrophy 2 | 103
Kidney disease 2 | 430
Neoplasm Invasiveness 2 | 161
Proteinuria 2 | 144
Seizures 2 | 596
atypical teratoid/rhabdoid tumor 2 | 357
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192

Target Family

Enzyme 27 | 4,145
Non-IDG 2 | 12,091

GO Process

proteolysis involved in cellul... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Prolyl endopeptidase FAP FAP Tchem Enzyme -2.37686 226.2 406
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial CLPX Tbio Enzyme -2.32024 211.2 76
Insulin-degrading enzyme IDE Tchem Enzyme -2.57779 392.8 331
Granzyme A GZMA Tbio Enzyme -2.51799 315.2 275
Cathepsin F CTSF Tchem Enzyme -1.64606 49.4 178
Pro-cathepsin H CTSH Tchem Enzyme -2.36930 222.0 253
Proteasome subunit alpha type-6 PSMA6 Tbio Enzyme -2.80973 614.4 288
Lysosomal protective protein CTSA Tchem Enzyme -3.07101 1162.7 300