Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal retina morphology 1 | 71
decreased caudal vertebrae num... 1 | 53
increased bone mineral density 1 | 72
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Cancer 3 | 2,499
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Breast cancer 2 | 3,578
Rheumatoid arthritis 2 | 1,191
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
psoriasis 2 | 6,694
Abnormal coordination 1 | 15
Absent speech 1 | 43
Acquired flat foot 1 | 72
Alagille syndrome 1 | 15
Arsenic Poisoning 1 | 62
Astigmatism 1 | 54
Autonomic nervous system disorders 1 | 19
Autosomal dominant polycystic kidney disease 1 | 31
Autosomal recessive polycystic kidney disease 1 | 41
BILIARY TRACT ABNORMALITY 1 | 16
Biliary Tract Diseases 1 | 16
Breast Neoplasms 1 | 445
Brugada Syndrome (disorder) 1 | 15
Brugada syndrome 1 | 29
Capuchin ears 1 | 17
Carcinoma, Pancreatic Ductal 1 | 20
Carcinoma, Renal Cell 1 | 124
Cardiomyopathy, Hypertrophic 1 | 24
Chromosome 17q12 deletion syndrome 1 | 16
Chronic kidney disease stage 5 1 | 31
Clubbing 1 | 9
Coarse facial features 1 | 108
Constipation 1 | 181
Corneal disease 1 | 31
Craniofacial Abnormalities 1 | 151
Cupped ears (finding) 1 | 17
Dermatologic disorders 1 | 93
Dysautonomia 1 | 20
Dyschezia 1 | 135
Elevated hepatic transaminases 1 | 81
Encephalopathies 1 | 43
Enophthalmos 1 | 75
Flatfoot 1 | 73
Frontotemporal dementia 1 | 51
Fuchs' endothelial dystrophy 1 | 24
Gastroesophageal reflux disease 1 | 110
Gastrointestinal system disease 1 | 54
Gout 1 | 106
Heart Diseases 1 | 43
Heartburn 1 | 78
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hypertrophic Cardiomyopathy 1 | 117
Hypomagnesemia 2, renal 1 | 4
Hypoplasia of corpus callosum 1 | 90
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Liver Cirrhosis, Experimental 1 | 769
Malignant tumor of prostate 1 | 26
Mammary Neoplasms 1 | 425
Microcephaly 1 | 166
Motor delay 1 | 147
Multicystic renal dysplasia, bilateral 1 | 2
Myopia 1 | 176
Narrow forehead 1 | 34
Neonatal abstinence syndrome 1 | 11
No development of motor milestones 1 | 147
Nonorganic psychosis 1 | 84
Obstruction of pelviureteric junction 1 | 8
Open mouth 1 | 45
Penile hypospadias 1 | 106
Peripheral Neuropathy 1 | 134
Pitt-Hopkins syndrome 1 | 20
Progressive mental retardation 1 | 37
Renal Cell Carcinoma 1 | 214
Renal Cell Carcinoma, Nonpapillary 1 | 7
Retinal disease 1 | 25
Severe mental retardation (I.Q. 20-34) 1 | 99
Short philtrum 1 | 53
Single transverse palmar crease 1 | 29
Skin Diseases 1 | 71
Spermatocele 1 | 4
Subclinical abnormal liver function tests 1 | 81
Sunken eyes 1 | 63
Tapering fingers (finding) 1 | 25
Thickened facial skin with coarse facial features 1 | 108
Widely spaced teeth 1 | 31
blepharophimosis, ptosis, and epicanthus inversus syndrome 1 | 8
maturity-onset diabetes of the young 1 | 32
nonverbal 1 | 43

Tissue

Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192

Target Family

Transcription Factor 5 | 1,400

GO Process

protein-DNA complex assembly 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hepatocyte nuclear factor 1-beta HNF1B Tbio Transcription Factor -2.63510 401.5 403
Transcription factor SOX-12 SOX12 Tbio Transcription Factor -0.86228 7.00 174
E3 SUMO-protein ligase PIAS1 PIAS1 Tbio Transcription Factor -1.86330 76.2 272
Transcription factor 4 TCF4 Tbio Transcription Factor -2.57908 320.1 249
Hairy/enhancer-of-split related with YRPW motif protein 2 HEY2 Tbio Transcription Factor -2.43307 261.2 173