Development Level

Tbio 105 | 11,445
Tdark 25 | 6,588
Tchem 9 | 1,598

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to t... 10 | 278
abnormal embryo size 8 | 220
preweaning lethality, incomple... 8 | 499
embryonic growth retardation 5 | 106
embryonic lethality prior to o... 5 | 239
abnormal behavior 4 | 298
abnormal bone structure 3 | 187
abnormal heart morphology 3 | 162
decreased circulating alanine ... 3 | 47
decreased circulating alkaline... 3 | 46
decreased circulating chloride... 3 | 30
decreased circulating fructosa... 3 | 30
decreased hemoglobin content 3 | 68
decreased startle reflex 3 | 75
increased circulating chloride... 3 | 41
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased mean platelet volume 3 | 45
short tibia 3 | 97
abnormal heart left ventricle ... 2 | 16
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
abnormal seminal vesicle morph... 2 | 114
anophthalmia 2 | 33
decreased blood urea nitrogen ... 2 | 51
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
dilated heart left ventricle 2 | 11
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating calcium ... 2 | 34
increased heart weight 2 | 62
increased red blood cell distr... 2 | 34
prenatal lethality 2 | 28
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal hindbrain development 1 | 16
abnormal joint morphology 1 | 23
abnormal midbrain development 1 | 20
abnormal pericardium morpholog... 1 | 26
abnormal placenta morphology 1 | 5
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vitelline vasculature... 1 | 6
abnormal vocalization 1 | 21
brachydactyly 1 | 19
corneal opacity 1 | 32
cystolithiasis 1 | 3
decreased body length 1 | 101
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged spleen 1 | 41
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
shortened PQ interval 1 | 7
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
small thymus 1 | 16
syndactyly 1 | 23
thick skin 1 | 4
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

ovarian cancer 97 | 8,520
Carcinoma 88 | 11,493
osteosarcoma 67 | 7,950
medulloblastoma, large-cell 61 | 6,241
atypical teratoid / rhabdoid tumor 57 | 5,112
glioblastoma 54 | 5,792
psoriasis 54 | 6,694
lung cancer 47 | 4,740
adult high grade glioma 39 | 3,801
ependymoma 39 | 4,679
Breast cancer 36 | 3,578
primitive neuroectodermal tumor 34 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
non-small cell lung cancer 31 | 2,890
group 3 medulloblastoma 30 | 4,104
Astrocytoma, Pilocytic 29 | 3,081
Cancer 27 | 2,499
oligodendroglioma 26 | 2,850
astrocytic glioma 25 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
pancreatic cancer 25 | 2,398
Kidney cancer 24 | 2,613
invasive ductal carcinoma 23 | 2,951
malignant mesothelioma 23 | 3,232
adrenocortical carcinoma 22 | 1,428
lung adenocarcinoma 21 | 2,716
subependymal giant cell astrocytoma 21 | 2,287
group 4 medulloblastoma 20 | 1,855
spina bifida 19 | 1,074
breast carcinoma 17 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
ulcerative colitis 17 | 1,819
Multiple myeloma 16 | 1,332
ductal carcinoma in situ 16 | 1,745
Pick disease 14 | 1,894
interstitial cystitis 14 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
tuberculosis 14 | 2,010
acute quadriplegic myopathy 13 | 1,158
colon cancer 13 | 1,478
lung carcinoma 13 | 2,843
Atopic dermatitis 12 | 952
Endometriosis 12 | 540
Rheumatoid arthritis 12 | 1,191
juvenile dermatomyositis 12 | 1,187
medulloblastoma 12 | 720
pituitary cancer 12 | 1,972
primary Sjogren syndrome 10 | 735
acute myeloid leukemia 9 | 783
astrocytoma 9 | 1,146
esophageal adenocarcinoma 9 | 737
Intellectual disability 8 | 1,016
active Crohn's disease 8 | 922
Liver cancer 7 | 604
Melanoma 7 | 711
cystic fibrosis 7 | 1,696
nasopharyngeal carcinoma 7 | 1,058
posterior fossa group A ependymoma 7 | 468
primary pancreatic ductal adenocarcinoma 7 | 1,109
Autosomal recessive predisposition 6 | 1,442
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Parkinson's disease 6 | 392
Poor school performance 6 | 645
cutaneous lupus erythematosus 6 | 1,057
gastric carcinoma 6 | 807
pediatric high grade glioma 6 | 1,064
tuberculosis and treatment for 6 months 6 | 409
Alzheimer's disease 5 | 658
Breast Neoplasms 5 | 445
Hypertension 5 | 396
Mammary Neoplasms 5 | 425
Pseudohypoaldosteronism 5 | 23
aldosterone-producing adenoma 5 | 665
hepatocellular carcinoma 5 | 547
non primary Sjogren syndrome sicca 5 | 891
pancreatic carcinoma 5 | 562
progressive supranuclear palsy 5 | 676
Colorectal Neoplasms 4 | 243
Endometrial cancer 4 | 311
Hypertensive disease 4 | 292
Multiple Sclerosis 4 | 540
Neurodegenerative disease 4 | 414
Short stature 4 | 531
Stevens-Johnson syndrome 4 | 92
Stomach Neoplasms 4 | 300
Tremor 4 | 113
Waldenstrons macroglobulinemia 4 | 765
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
gastric cancer 4 | 459
Epilepsy 3 | 792
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Seizures 3 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 139 | 18,159
Blood and immune system 138 | 16,909
Digestive Tract 138 | 17,369
Female tissues 138 | 17,400
Liver and Pancreas 138 | 16,750
Male tissues 138 | 17,142
Nervous System 138 | 16,725
Respiratory system 138 | 16,393
Skin and soft tissues 138 | 17,230
Urinary Tract 137 | 16,678
Cardiovascular System 136 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 62 | 4,145
Kinase 6 | 634
Epigenetic 1 | 242

GO Process

protein ubiquitination involve... 139 | 139
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Anaphase-promoting complex subunit 7 ANAPC7 Tbio Enzyme -0.17118 1.40 73
CDK2-associated and cullin domain-containing protein 1 CACUL1 Tbio Non-IDG -0.58734 5.65 98
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
E3 ubiquitin-protein ligase RNF19A RNF19A Tbio Enzyme -1.12489 15.5 142
BTB/POZ domain-containing protein 9 BTBD9 Tbio Non-IDG -1.32647 22.9 104
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143