Development Level

Tbio 56 | 11,445
Tchem 6 | 1,598
Tdark 6 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal heart morphology 2 | 162
decreased lean body mass 2 | 135
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal social-conspecific in... 1 | 3
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased lumbar vertebrae num... 1 | 2
decreased sacral vertebrae num... 1 | 1
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased lumbar vertebrae num... 1 | 1
increased sacral vertebrae num... 1 | 1
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
thrombocytopenia 1 | 56
vertebral transformation 1 | 12

Disease

Carcinoma 58 | 11,493
lung cancer 39 | 4,740
osteosarcoma 39 | 7,950
ovarian cancer 38 | 8,520
medulloblastoma, large-cell 36 | 6,241
group 3 medulloblastoma 32 | 4,104
atypical teratoid / rhabdoid tumor 26 | 5,112
psoriasis 26 | 6,694
glioblastoma 25 | 5,792
non-small cell lung cancer 21 | 2,890
Breast cancer 19 | 3,578
adult high grade glioma 19 | 3,801
primitive neuroectodermal tumor 19 | 3,035
Cancer 18 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Kidney cancer 17 | 2,613
ependymoma 17 | 4,679
malignant mesothelioma 16 | 3,232
oligodendroglioma 16 | 2,850
astrocytic glioma 14 | 2,597
dermatomyositis 13 | 966
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
invasive ductal carcinoma 11 | 2,951
Multiple myeloma 10 | 1,332
Waldenstrons macroglobulinemia 10 | 765
acute quadriplegic myopathy 10 | 1,158
Rheumatoid arthritis 9 | 1,191
breast carcinoma 9 | 1,638
Astrocytoma, Pilocytic 8 | 3,081
Pick disease 8 | 1,894
colon cancer 8 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
tuberculosis 8 | 2,010
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
juvenile dermatomyositis 7 | 1,187
lung carcinoma 7 | 2,843
ulcerative colitis 7 | 1,819
Atopic dermatitis 6 | 952
ductal carcinoma in situ 6 | 1,745
lung adenocarcinoma 6 | 2,716
nasopharyngeal carcinoma 6 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
Autosomal recessive predisposition 5 | 1,442
Endometriosis 5 | 540
Intellectual disability 5 | 1,016
Amyotrophic lateral sclerosis 4 | 451
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
interstitial lung disease 4 | 298
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
primary Sjogren syndrome 4 | 735
sonic hedgehog group medulloblastoma 4 | 467
subependymal giant cell astrocytoma 4 | 2,287
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Highly variable severity 3 | 157
Leukemia 3 | 104
Melanoma 3 | 711
Mental and motor retardation 3 | 608
Neurodegenerative disease 3 | 414
Optic Atrophy 3 | 242
Photodysphoria 3 | 121
Photophobia 3 | 121
Renal Cell Carcinoma 3 | 214
Schizophrenia 3 | 1,160
Sensorineural Hearing Loss (disorder) 3 | 284
Short stature 3 | 531
Variable expressivity 3 | 157
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
Adenoid Cystic Carcinoma 2 | 99
Anemia 2 | 365
Anteverted nostril 2 | 191
Broad flat nasal bridge 2 | 236
Colonic Neoplasms 2 | 142
Hypersensitivity reaction type II disease 2 | 253
Lung Neoplasms 2 | 232
Multiple Sclerosis 2 | 540
Nasal bridge wide 2 | 236
Peripheral vascular disease 2 | 87
Polycystic ovary syndrome 2 | 360
Stomach Neoplasms 2 | 300
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
esophageal adenocarcinoma 2 | 737
spina bifida 2 | 1,074

Tissue

Blood and immune system 69 | 16,909
Digestive Tract 69 | 17,369
Endocrine System 69 | 18,159
Female tissues 69 | 17,400
Liver and Pancreas 69 | 16,750
Male tissues 69 | 17,142
Nervous System 69 | 16,725
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678
Respiratory system 68 | 16,393
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 13 | 4,145
Transcription Factor 10 | 1,400
Epigenetic 3 | 242
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

protein sumoylation 70 | 70
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
E3 SUMO-protein ligase ZNF451 ZNF451 Tbio Transcription Factor -2.42090 254.4 71
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.23703 17.9 139
E3 SUMO-protein ligase PIAS3 PIAS3 Tbio Transcription Factor -1.74449 53.4 174
RING finger protein 212B RNF212B Tdark Non-IDG 0.44 0.33 3
Probable E3 SUMO-protein ligase RNF212 RNF212 Tbio Enzyme -0.94925 8.45 87
E3 SUMO-protein ligase KIAA1586 KIAA1586 Tdark Non-IDG 0.70 0.13 60