Development Level

Tbio 127 | 11,445
Tchem 23 | 1,598
Tclin 5 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to t... 4 | 278
enlarged heart 4 | 210
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
decreased startle reflex 3 | 75
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased or absent threshold ... 2 | 101
abnormal brain morphology 1 | 13
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal limb position 1 | 3
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
cataract 1 | 92
cleft palate 1 | 8
corneal opacity 1 | 32
cyanosis 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
fused cornea and lens 1 | 5
hydroencephaly 1 | 14
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
long tibia 1 | 25
male infertility 1 | 123
prolonged RR interval 1 | 8
short tibia 1 | 97
small seminal vesicle 1 | 10
small testis 1 | 58
thin skin 1 | 2
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23

Disease

ovarian cancer 105 | 8,520
Carcinoma 99 | 11,493
osteosarcoma 79 | 7,950
psoriasis 78 | 6,694
medulloblastoma, large-cell 72 | 6,241
lung cancer 70 | 4,740
glioblastoma 65 | 5,792
atypical teratoid / rhabdoid tumor 57 | 5,112
Cancer 50 | 2,499
Breast cancer 43 | 3,578
ependymoma 42 | 4,679
group 3 medulloblastoma 40 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
adult high grade glioma 36 | 3,801
Multiple myeloma 34 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
lung adenocarcinoma 33 | 2,716
oligodendroglioma 33 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
non-small cell lung cancer 32 | 2,890
invasive ductal carcinoma 31 | 2,951
pancreatic cancer 31 | 2,398
malignant mesothelioma 30 | 3,232
primitive neuroectodermal tumor 30 | 3,035
Astrocytoma, Pilocytic 27 | 3,081
astrocytic glioma 27 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
diabetes mellitus 26 | 1,728
Waldenstrons macroglobulinemia 24 | 765
colon cancer 22 | 1,478
Pick disease 21 | 1,894
acute quadriplegic myopathy 21 | 1,158
breast carcinoma 21 | 1,638
tuberculosis 21 | 2,010
ulcerative colitis 21 | 1,819
Breast Neoplasms 20 | 445
Kidney cancer 20 | 2,613
Mammary Neoplasms 20 | 425
lung carcinoma 20 | 2,843
pituitary cancer 20 | 1,972
subependymal giant cell astrocytoma 20 | 2,287
Autosomal recessive predisposition 19 | 1,442
astrocytoma 19 | 1,146
dermatomyositis 19 | 966
interstitial cystitis 19 | 2,312
juvenile dermatomyositis 19 | 1,187
Intellectual disability 18 | 1,016
ductal carcinoma in situ 18 | 1,745
group 4 medulloblastoma 17 | 1,855
Rheumatoid arthritis 16 | 1,191
Parkinson's disease 15 | 392
Schizophrenia 15 | 1,160
adrenocortical carcinoma 15 | 1,428
Neurodegenerative disease 14 | 414
Seizures 13 | 596
Epilepsy 12 | 792
Hypoplastic mandible condyle 12 | 275
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
Prostatic Neoplasms 12 | 495
acute myeloid leukemia 12 | 783
pediatric high grade glioma 12 | 1,064
HIV Infections 11 | 102
medulloblastoma 11 | 720
primary pancreatic ductal adenocarcinoma 11 | 1,109
Cataract 10 | 297
Cognitive delay 10 | 608
Dull intelligence 10 | 645
Global developmental delay 10 | 608
Liver Cirrhosis, Experimental 10 | 769
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental and motor retardation 10 | 608
Mental deficiency 10 | 645
Poor school performance 10 | 645
Stomach Neoplasms 10 | 300
Atopic dermatitis 9 | 952
Bipolar Disorder 9 | 666
Crohn's disease 9 | 321
Glaucoma 9 | 239
Major Depressive Disorder 9 | 301
Melanoma 9 | 711
Renal Cell Carcinoma 9 | 214
active Crohn's disease 9 | 922
esophageal adenocarcinoma 9 | 737
pancreatic carcinoma 9 | 562
spina bifida 9 | 1,074
Alzheimer's disease 8 | 658
Depressive disorder 8 | 409
Down syndrome 8 | 499
Lens Opacities 8 | 231
Liver carcinoma 8 | 240
Strabismus 8 | 270
aldosterone-producing adenoma 8 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
fibroadenoma 8 | 559
gastric cancer 8 | 459
hepatocellular carcinoma 8 | 547
nasopharyngeal carcinoma 8 | 1,058

Tissue

Digestive Tract 158 | 17,369
Endocrine System 158 | 18,159
Female tissues 158 | 17,400
Skin and soft tissues 158 | 17,230
Urinary Tract 157 | 16,678
Blood and immune system 156 | 16,909
Liver and Pancreas 156 | 16,750
Male tissues 156 | 17,142
Respiratory system 156 | 16,393
Nervous System 155 | 16,725
Cardiovascular System 152 | 15,192

Target Family

Non-IDG 104 | 12,091
Enzyme 28 | 4,145
Kinase 14 | 634
Transcription Factor 9 | 1,400
Transporter 3 | 473
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

protein stabilization 160 | 160
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Huntingtin-interacting protein K HYPK Tbio Non-IDG -0.84672 8.89 4
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.26984 173.7 468
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
Histone H1.5 HIST1H1B Tbio Non-IDG -2.13224 134.1 103
Transcription initiation factor TFIID subunit 9B TAF9B Tbio Non-IDG -1.38372 23.5 105
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162