Development Level

Tbio 9 | 11,445
Tclin 1 | 613

IMPC Phenotype

decreased prepulse inhibition 1 | 82
increased circulating aspartat... 1 | 15
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
psoriasis 5 | 6,694
lung cancer 4 | 4,740
Cancer 3 | 2,499
Neurodegenerative disease 3 | 414
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
Ataxia, Appendicular 2 | 25
Ataxia, Truncal 2 | 21
Atrophy of cerebellum 2 | 103
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Breast cancer 2 | 3,578
Cerebellar degeneration 2 | 103
Depressive disorder 2 | 409
Infratentorial atrophy 2 | 103
Machado-Joseph disease 2 | 18
Mental Depression 2 | 333
Multiple myeloma 2 | 1,332
Optic Atrophy 2 | 242
Progressive disorder 2 | 142
Rheumatoid arthritis 2 | 1,191
Short nose 2 | 132
Short stature 2 | 531
Small nose 2 | 132
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
Abnormality of epiphysis morphology 1 | 39
Atrial Septal Defects 1 | 85
Autosomal dominant cerebellar ataxia 1 | 33
Big calvaria 1 | 147
Brachydactyly 1 | 156
Central cleft of nose 1 | 3
Death in early childhood 1 | 82
Death in infancy 1 | 82
Defective enamel matrix 1 | 35
Defective tooth enamel 1 | 31
Deglutition Disorders 1 | 132
Dental Enamel Hypoplasia 1 | 43
Dental abnormalities 1 | 60
Dilated fourth ventricle 1 | 4
Diplopia 1 | 8
Distal amyotrophy 1 | 51
Dysmetric saccades 1 | 9
Dysplasia of tooth enamel 1 | 35
Dystrophic tooth enamel 1 | 31
Enamel abnormalities 1 | 31
Flat face 1 | 52
Friedreich ataxia 1 | 24
Gait, Unsteady 1 | 29
Hypoplastic feet 1 | 66
Hypoplastic iliac wing 1 | 19
Impaired horizontal smooth pursuit 1 | 6
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Knee joint valgus deformity 1 | 56
Late tooth eruption 1 | 61
Metaphyseal chondrodysplasia 1 | 7
Midline defect of the nose 1 | 3
Mild Mental Retardation 1 | 70
Multiple system atrophy 1 | 29
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Narcolepsy 1 | 72
Nerve Degeneration 1 | 121
ODONTOID HYPOPLASIA 1 | 16
Olivopontocerebellar atrophy 1 | 9
Osteoporosis 1 | 363
Ovarian Neoplasms 1 | 102
Overfolded helix 1 | 24
PARKINSON DISEASE, LATE-ONSET 1 | 20
Platyspondyly 1 | 56
Postural instability 1 | 19
Progressive cerebellar ataxia 1 | 13
Progressive multifocal leukoencephalopathy 1 | 25
Reflex, Ankle, Absent 1 | 8
Restless legs syndrome 1 | 27
Rhizomelia 1 | 25
Short hands 1 | 50
Short phalanx of finger 1 | 32
Short upper arms 1 | 16
Sphincter disturbances 1 | 16
Spinocerebellar Ataxias 1 | 34
Spinocerebellar ataxia type 1 1 | 16
Spinocerebellar ataxia type 2 1 | 23
Spinocerebellar tract degeneration 1 | 4
Thin dental enamel 1 | 35
Tooth Abnormalities 1 | 69
X-linked dominant 1 | 57
ovarian neoplasm 1 | 99

Tissue

Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 3 | 12,091
Epigenetic 1 | 242

GO Process

protein quality control for mi... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lon protease homolog 2, peroxisomal LONP2 Tbio Enzyme -1.00177 8.20 100
ATP-dependent zinc metalloprotease YME1L1 YME1L1 Tbio Enzyme -2.42377 268.0 75
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase NGLY1 Tbio Enzyme -1.92615 77.4 32
Lon protease homolog, mitochondrial LONP1 Tbio Enzyme -2.24805 169.6 174
Ataxin-3-like protein ATXN3L Tbio Non-IDG -0.28506 1.65 37
Metalloendopeptidase OMA1, mitochondrial OMA1 Tbio Enzyme -1.77371 54.7 40
E3 ubiquitin-protein ligase CHIP STUB1 Tbio Enzyme -2.96877 926.8 351
Ubiquitin-conjugating enzyme E2 W UBE2W Tbio Non-IDG -1.05706 7.31 108
Histone deacetylase 6 HDAC6 Tclin Epigenetic -2.72354 545.3 725
Ataxin-3 ATXN3 Tbio Non-IDG -2.89207 773.7 230