Development Level

Tbio 13 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased heart rate variabili... 1 | 13
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28

Disease

Autosomal recessive predisposition 6 | 1,442
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
Atherosclerosis 4 | 291
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
Afibrinogenemia 3 | 4
Afibrinogenemia, congenital 3 | 3
Astrocytoma, Pilocytic 3 | 3,081
Bleeding tendency 3 | 37
Cancer 3 | 2,499
Congenital afibrinogenemia 3 | 11
Congenital hypofibrinogenemia 3 | 3
Dysfibrinogenemia, Congenital 3 | 3
Epistaxis 3 | 43
Familial dysfibrinogenemia 3 | 3
Familial hypofibrinogenemia 3 | 3
Gastrointestinal Hemorrhage 3 | 52
Gingival Hemorrhage 3 | 18
Hypofibrinogenemia 3 | 4
Intermenstrual heavy bleeding 3 | 4
Joint swelling 3 | 26
Multiple myeloma 3 | 1,332
Schizophrenia 3 | 1,160
Spontaneous abortion 3 | 113
Thrombophilia 3 | 38
Venous Thrombosis 3 | 47
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Catecholaminergic polymorphic ventricular tachycardia 2 | 12
Cryptorchidism 2 | 296
Osteoporosis 2 | 363
Pick disease 2 | 1,894
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
11 pairs of ribs 1 | 7
Amyloidosis 1 | 67
Androgen insensitivity syndrome 1 | 12
Atrioventricular block 1 | 35
Atrioventricular nodal disease 1 | 10
Autoimmune thyroiditis 1 | 27
Autosomal recessive polycystic kidney disease 1 | 41
Charcot-Marie-Tooth Disease, Axonal, Type 2E 1 | 2
Charcot-Marie-Tooth disease, Type 1C 1 | 2
Claw hand 1 | 26
Cone-shaped epiphyses of phalanges 1 | 15
Decreased motor NCV 1 | 22
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Edema 1 | 81
Embryo Loss 1 | 7
Flared iliac wings 1 | 13
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Generalized hypotonia 1 | 37
Graves' disease 1 | 24
Hammer Toe 1 | 23
Hematuria 1 | 36
Hypoplastic finger 1 | 17
Idiopathic scoliosis 1 | 31
Irregular myelin foldings 1 | 4
Keloid 1 | 37
Metaphyseal chondrodysplasia 1 | 7
Metaphyseal cupping 1 | 10
Metaphyseal irregularity 1 | 23
Muscle Cramp 1 | 55
Myalgia 1 | 54
Myofibrillar myopathy 1 1 | 6
Nephrotic Syndrome 1 | 78
Oculogyric crisis 1 | 4
Onion bulb formation 1 | 19
Ornithine carbamoyltransferase deficiency 1 | 12
Platyspondyly 1 | 56
Porencephaly 1 | 20
Segmental demyelination/remyelination 1 | 8
Short finger 1 | 17
Short hands 1 | 50
Short phalanx of finger 1 | 32
Short ribs 1 | 30
Short tubular bones 1 | 22
Syncope 1 | 22
Tachycardia, Ventricular 1 | 22
Thrombosis 1 | 46
Ulnar claw 1 | 6
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy 1 | 4

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 11 | 15,192
Nervous System 11 | 16,725

Target Family

Non-IDG 10 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GO Process

protein polymerization 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 Tbio Enzyme -2.88891 707.6 227
Calsequestrin-1 CASQ1 Tbio Non-IDG -1.96476 86.8 103
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.45155 278.6 88
Fibrinogen beta chain FGB Tbio Non-IDG -2.09043 116.8 352
ADP-ribosylation factor-like protein 6 ARL6 Tbio Enzyme -0.58263 3.92 86
Calsequestrin-2 CASQ2 Tbio Non-IDG -1.93799 89.4 204