Development Level

Tbio 48 | 11,445
Tchem 13 | 1,598
Tclin 4 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased vertical activity 3 | 208
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
decreased grip strength 2 | 116
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
enlarged urinary bladder 1 | 8
hydroencephaly 1 | 14
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 49 | 11,493
ovarian cancer 42 | 8,520
osteosarcoma 38 | 7,950
lung cancer 30 | 4,740
psoriasis 26 | 6,694
medulloblastoma, large-cell 24 | 6,241
glioblastoma 23 | 5,792
ependymoma 22 | 4,679
malignant mesothelioma 22 | 3,232
Breast cancer 18 | 3,578
Cancer 18 | 2,499
atypical teratoid / rhabdoid tumor 18 | 5,112
group 3 medulloblastoma 18 | 4,104
Kidney cancer 15 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Astrocytoma, Pilocytic 14 | 3,081
diabetes mellitus 14 | 1,728
lung adenocarcinoma 14 | 2,716
pancreatic cancer 14 | 2,398
subependymal giant cell astrocytoma 14 | 2,287
tuberculosis 14 | 2,010
interstitial cystitis 13 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
invasive ductal carcinoma 13 | 2,951
lung carcinoma 13 | 2,843
Multiple myeloma 12 | 1,332
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
non primary Sjogren syndrome sicca 11 | 891
ulcerative colitis 11 | 1,819
Alzheimer's disease 10 | 658
Autosomal recessive predisposition 10 | 1,442
Bipolar Disorder 10 | 666
Pick disease 10 | 1,894
astrocytic glioma 10 | 2,597
cutaneous lupus erythematosus 10 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
non-small cell lung cancer 10 | 2,890
Atopic dermatitis 8 | 952
acute quadriplegic myopathy 8 | 1,158
cystic fibrosis 8 | 1,696
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
astrocytoma 7 | 1,146
Down syndrome 6 | 499
Epilepsy 6 | 792
Multiple Sclerosis 6 | 540
Neurodegenerative disease 6 | 414
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
Waldenstrons macroglobulinemia 6 | 765
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
Crohn's disease 5 | 321
Dysarthria 5 | 192
Hypertension 5 | 396
Intellectual disability 5 | 1,016
Prostatic Neoplasms 5 | 495
Small head 5 | 374
Vascular disease 5 | 319
acute myeloid leukemia 5 | 783
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
Anemia 4 | 365
Arthritis, Rheumatoid 4 | 174
Autistic Disorder 4 | 364
Bilateral fifth finger clinodactyly 4 | 110
Curvature of little finger 4 | 110
Depressive disorder 4 | 409
Dull intelligence 4 | 645
Infertility 4 | 188
Low intelligence 4 | 645
Male infertility 4 | 206
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Mood Disorders 4 | 184
Motor delay 4 | 147
Neuropathy 4 | 261
No development of motor milestones 4 | 147
Obesity 4 | 678
Parkinson's disease 4 | 392
Polycystic ovary syndrome 4 | 360
Poor school performance 4 | 645
Seizures 4 | 596
Skin cancer 4 | 469
Slow progression 4 | 89
Weight decreased 4 | 103
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
juvenile dermatomyositis 4 | 1,187
progressive supranuclear palsy 4 | 676

Tissue

Endocrine System 68 | 18,159
Blood and immune system 67 | 16,909
Digestive Tract 67 | 17,369
Female tissues 67 | 17,400
Liver and Pancreas 67 | 16,750
Male tissues 67 | 17,142
Nervous System 67 | 16,725
Respiratory system 67 | 16,393
Urinary Tract 67 | 16,678
Cardiovascular System 66 | 15,192
Skin and soft tissues 66 | 17,230

Target Family

Non-IDG 44 | 12,091
Enzyme 9 | 4,145
Kinase 8 | 634
Ion Channel 3 | 344
Transporter 2 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GO Process

protein oligomerization 69 | 69
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Box C/D snoRNA protein 1 ZNHIT6 Tbio Non-IDG 0.48 0.74 87
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
Diacylglycerol kinase eta DGKH Tbio Kinase -1.45863 29.5 92
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.64193 42.6 207