Development Level

Tbio 37 | 10,625
Tchem 12 | 1,890
Tclin 4 | 602
Tdark 2 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

impaired glucose tolerance 2 | 52
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal heart morphology 1 | 51
abnormal lung morphology 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating potassiu... 1 | 31
increased lean body mass 1 | 107
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 32 | 8,484
osteosarcoma 29 | 7,933
lung cancer 26 | 4,466
psoriasis 22 | 6,685
glioblastoma 17 | 5,572
malignant mesothelioma 16 | 3,162
medulloblastoma, large-cell 16 | 6,234
Breast cancer 14 | 3,094
pancreatic cancer 14 | 2,300
Cancer 13 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
lung adenocarcinoma 13 | 2,713
interstitial cystitis 12 | 2,299
subependymal giant cell astrocytoma 12 | 2,287
diabetes mellitus 11 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
invasive ductal carcinoma 11 | 2,950
lung carcinoma 11 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
pediatric high grade glioma 11 | 2,712
pilocytic astrocytoma 11 | 3,086
ulcerative colitis 11 | 2,087
Multiple myeloma 10 | 1,327
atypical teratoid / rhabdoid tumor 10 | 4,369
ependymoma 10 | 2,514
cutaneous lupus erythematosus 9 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
non-small cell lung cancer 9 | 2,798
tuberculosis 9 | 1,557
Atopic dermatitis 8 | 944
cystic fibrosis 8 | 1,665
oligodendroglioma 8 | 2,849
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,031
Carcinoma 7 | 2,147
group 4 medulloblastoma 7 | 1,875
non primary Sjogren syndrome sicca 7 | 840
posterior fossa group A ependymoma 7 | 1,511
primary pancreatic ductal adenocarcinoma 7 | 1,271
astrocytic glioma 6 | 2,241
astrocytoma 6 | 1,493
group 3 medulloblastoma 6 | 2,254
Alzheimer's disease 5 | 644
Bipolar Disorder 5 | 266
Crohn's disease 5 | 304
Down syndrome 5 | 548
Multiple Sclerosis 5 | 498
Prostatic Neoplasms 5 | 471
Rheumatoid Arthritis 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,157
dermatomyositis 5 | 933
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 832
spina bifida 5 | 1,064
Autistic Disorder 4 | 320
Hypertension 4 | 287
Male infertility 4 | 170
Neurodegenerative disease 4 | 383
Pick disease 4 | 1,893
Renal Cell Carcinoma 4 | 199
acute myeloid leukemia 4 | 780
adult high grade glioma 4 | 2,148
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
juvenile dermatomyositis 4 | 1,189
medulloblastoma 4 | 1,524
posterior fossa group B ependymoma 4 | 1,530
primary Sjogren syndrome 4 | 789
Blau syndrome 3 | 8
Chronic Lymphocytic Leukemia 3 | 242
Colitis 3 | 46
Diabetes Mellitus, Experimental 3 | 106
Hypertensive disease 3 | 193
IGA Glomerulonephritis 3 | 454
Infertility 3 | 163
Lymphoma 3 | 56
Major Depressive Disorder 3 | 106
Myocardial Infarction 3 | 126
Myocardial Ischemia 3 | 169
Obesity 3 | 616
Oculodentodigital dysplasia 3 | 14
Parkinson's disease 3 | 364
Polycystic Ovary Syndrome 3 | 332
Vascular disease 3 | 281
active Crohn's disease 3 | 918
adrenocortical carcinoma 3 | 1,427
glioblastoma multiforme 3 | 347
interstitial lung disease 3 | 291
sonic hedgehog group medulloblastoma 3 | 1,482
systemic lupus erythematosus 3 | 156
tuberculosis and treatment for 3 months 3 | 327
Endometriosis 2 | 535
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
mucosa-associated lymphoid tissue lymphoma 2 | 480
pancreatic carcinoma 2 | 567
urothelial carcinoma 2 | 318

Tissue

Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115
Urinary Tract 54 | 18,444
Blood and immune system 52 | 17,995

Target Family

Non-IDG 32 | 11,971
Enzyme 9 | 4,146
Kinase 8 | 634
Ion Channel 2 | 341
Transporter 2 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

protein oligomerization 55 | 55
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.61845 51.3 82
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial HSCB Tbio Non-IDG -1.61949 45.8 33
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.55538 356.6 142
B-cell lymphoma/leukemia 10 BCL10 Tbio Non-IDG -0.69461 4.24 679
Diacylglycerol kinase eta DGKH Tbio Kinase -1.39310 28.9 73
Eppin EPPIN Tbio Non-IDG -1.49913 19.7 59
Caveolin-2 CAV2 Tbio Non-IDG -2.41179 245.9 248
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.18465 1655.7 459
Box C/D snoRNA protein 1 ZNHIT6 Tbio Non-IDG 0.65 0.21 76