Development Level

Tbio 16 | 11,445
Tchem 7 | 1,598
Tdark 7 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased total body fat amoun... 2 | 207
increased circulating creatini... 2 | 38
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased startle reflex 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 22 | 8,520
osteosarcoma 18 | 7,950
Carcinoma 17 | 11,493
Multiple myeloma 11 | 1,332
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
ependymoma 10 | 4,679
psoriasis 10 | 6,694
Cancer 8 | 2,499
Pick disease 8 | 1,894
atypical teratoid / rhabdoid tumor 8 | 5,112
lung cancer 8 | 4,740
Waldenstrons macroglobulinemia 7 | 765
astrocytic glioma 7 | 2,597
dermatomyositis 7 | 966
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
acute quadriplegic myopathy 6 | 1,158
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Amyotrophic lateral sclerosis 4 | 451
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
hepatocellular carcinoma 4 | 547
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
Astrocytoma, Pilocytic 3 | 3,081
Muscle Weakness 3 | 170
Stomach Neoplasms 3 | 300
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
gastric cancer 3 | 459
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
ulcerative colitis 3 | 1,819
Adenocarcinoma 2 | 122
Animal Mammary Neoplasms 2 | 136
Autosomal recessive predisposition 2 | 1,442
Cerebrovascular disease 2 | 238
Cleft Palate 2 | 271
Dysarthria 2 | 192
Dyslexia 2 | 43
Epilepsy 2 | 792
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 2 | 13
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Neurodegenerative disease 2 | 414
Schizophrenia 2 | 1,160
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
chronic rhinosinusitis 2 | 512
ductal carcinoma in situ 2 | 1,745
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
11 pairs of ribs 1 | 7
Acute coronary syndrome 1 | 39
Aspergillosis 1 | 26
Back Pain 1 | 7
Behavioral variant of frontotemporal dementia 1 | 8
Compulsive hoarding 1 | 7
Cystinuria 1 | 18
Developmental arithmetic disorder 1 | 8
Dysphasia 1 | 23
Echolalia 1 | 12
Ehrlichiosis 1 | 9
Embryo Loss 1 | 7
Excess nuchal skin 1 | 30
Flexion contracture - elbow 1 | 32
Hypernasal voice 1 | 39
Hyperorality 1 | 7
Nasal voice 1 | 39
Porencephaly 1 | 20
Postnatal growth retardation 1 | 57
Reflex, Ankle, Absent 1 | 8
Restlessness 1 | 14
Restrictive behavior, interests, and activities 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Shoulder girdle muscle atrophy 1 | 6
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Winged scapula 1 | 23
Xerostomia 1 | 42
genital abnormal 1 | 17
reproductive system abnormality 1 | 17

Tissue

Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Digestive Tract 30 | 17,369
Respiratory system 30 | 16,393
Urinary Tract 30 | 16,678
Blood and immune system 29 | 16,909
Cardiovascular System 29 | 15,192

Target Family

Enzyme 15 | 4,145
Non-IDG 13 | 12,091
Epigenetic 3 | 242

GO Process

protein methylation 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A GSPT1 Tbio Enzyme -1.35573 22.8 99
Eukaryotic peptide chain release factor subunit 1 ETF1 Tbio Enzyme -1.75590 53.5 113
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363
Small nuclear ribonucleoprotein Sm D3 SNRPD3 Tbio Non-IDG -1.64561 38.0 165
Protein BTG1 BTG1 Tbio Non-IDG 0.13 1.00 154
Protein FAM98B FAM98B Tdark Non-IDG 0.13 0.71 81
EEF1A lysine methyltransferase 2 EEF1AKMT2 Tdark Enzyme -0.14613 1.69 95
Protein-lysine methyltransferase METTL21D VCPKMT Tbio Enzyme -0.35402 2.63 12
Protein arginine N-methyltransferase 3 PRMT3 Tchem Epigenetic -1.33457 21.2 254