Development Level

Tbio 2 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal seminal vesicle morph... 1 | 114
bleb 1 | 2
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
prenatal lethality prior to he... 1 | 87

Disease

Congenital disorder of glycosylation 3 | 54
Autosomal recessive predisposition 2 | 1,442
Congenital muscular dystrophy 2 | 29
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Elevated hepatic transaminases 2 | 81
Hepatic enzyme increased 2 | 81
Isoelectric focusing of serum transferrin consistent with CDG type I 2 | 10
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Muscular dystrophy 2 | 75
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Abnormality of vision 1 | 40
Ankle contracture 1 | 9
Antithrombin III deficiency 1 | 14
Blindness, Cortical 1 | 24
Breast cancer 1 | 3,578
Budd-Chiari syndrome 1 | 12
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iaa 1 | 1
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Ie 1 | 1
Cardiomyopathy, Dilated 1 | 83
Citrullinemia 1 | 14
Concave bridge of nose 1 | 195
Congenital Camptodactyly 1 | 40
Congenital Disorder of Glycosylation, Type Io 1 | 1
Congenital disorder of glycosylation type 1E 1 | 1
Cortical visual impairment 1 | 24
DPM3-CDG 1 | 1
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Disorder of macula of retina 1 | 6
Downward slant of palpebral fissure 1 | 158
Electroencephalogram abnormal 1 | 101
Endometriosis 1 | 540
Epilepsy 1 | 792
Erythromelalgia 1 | 7
Essential thrombocythemia 1 | 10
Facial neuralgia 1 | 3
Failure to gain weight 1 | 365
Flat back of the head 1 | 26
Flat occiput 1 | 26
Global developmental delay, severe 1 | 47
Hemangioma 1 | 69
Hepatomegaly 1 | 285
High, narrow palate 1 | 32
Highly variable severity 1 | 157
Hypoplasia involving bones of the upper limbs 1 | 3
Hypoplastic mandible condyle 1 | 275
Infantile onset 1 | 238
Juvenile Myelomonocytic Leukemia 1 | 21
Leukemia 1 | 104
Lower limb hyperreflexia 1 | 10
Mandibular hypoplasia 1 | 275
Mastocytosis 1 | 27
Melanoma 1 | 711
Microcephaly 1 | 166
Multiple myeloma 1 | 1,332
Multiple personality disorder 1 | 8
Muscle Weakness 1 | 170
Muscle biopsy shows dystrophic changes 1 | 39
Myelofibrosis 1 | 14
Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 1 | 1
Nail dysplasia 1 | 52
Nystagmus 1 | 317
Optic Atrophy 1 | 242
Partial thromboplastin time increased (finding) 1 | 11
Pediatric failure to thrive 1 | 365
Polycythemia vera 1 | 27
Pontocerebellar atrophy 1 | 2
Portal vein thrombosis 1 | 12
Postnatal microcephaly 1 | 24
Progressive disorder 1 | 142
Protein C deficiency 1 | 19
Protein S deficiency 1 | 6
Reduced protein S activity 1 | 2
Respiratory distress 1 | 43
Retinal Diseases 1 | 55
Rimmed vacuoles on biopsy 1 | 15
Seizures 1 | 596
Severe psychomotor retardation 1 | 47
Short hands 1 | 50
Small hand 1 | 36
Small head 1 | 374
Smooth philtrum 1 | 43
Spider Veins 1 | 17
Splenomegaly 1 | 190
Strabismus 1 | 270
Telangiectasis 1 | 36
Thrombocytosis 1 | 38
Tremor 1 | 113
Variable expressivity 1 | 157
Variation in muscle fiber size 1 | 16
Waddling gait 1 | 34
active Crohn's disease 1 | 922
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

GO Process

protein mannosylation 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dolichol-phosphate mannosyltransferase subunit 1 DPM1 Tbio Enzyme -2.44968 261.7 86
Dehydrodolichyl diphosphate synthase complex subunit NUS1 NUS1 Tbio Enzyme -1.37569 28.5 55
Dolichol-phosphate mannosyltransferase subunit 3 DPM3 Tdark Enzyme -0.75862 5.50 28