Development Level

Tbio 98 | 11,651
Tclin 11 | 612
Tchem 9 | 1,388
Tdark 7 | 6,593

Collection

RFA-RM-18-021 5 | 328
Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 5 | 298
preweaning lethality, incomple... 5 | 499
hyperactivity 4 | 148
increased circulating alkaline... 3 | 122
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
decreased lactate dehydrogenas... 2 | 16
decreased mean corpuscular hem... 2 | 50
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
prenatal lethality 2 | 28
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
anophthalmia 1 | 33
cleft palate 1 | 8
corneal opacity 1 | 32
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
facial cleft 1 | 3
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased basophil cell number 1 | 7
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
prenatal lethality prior to he... 1 | 87
thrombocytosis 1 | 27
trunk curl 1 | 16

Disease

Carcinoma 84 | 11,493
ovarian cancer 75 | 8,520
medulloblastoma, large-cell 65 | 6,241
osteosarcoma 65 | 7,950
glioblastoma 64 | 5,792
atypical teratoid / rhabdoid tumor 61 | 5,112
psoriasis 60 | 6,694
ependymoma 55 | 4,679
adult high grade glioma 47 | 3,801
Astrocytoma, Pilocytic 44 | 3,081
group 3 medulloblastoma 43 | 4,104
lung cancer 41 | 4,740
primitive neuroectodermal tumor 41 | 3,035
lung carcinoma 40 | 2,843
Breast cancer 38 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
Kidney cancer 36 | 2,613
oligodendroglioma 36 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
subependymal giant cell astrocytoma 33 | 2,287
astrocytic glioma 32 | 2,597
invasive ductal carcinoma 32 | 2,951
malignant mesothelioma 30 | 3,232
lung adenocarcinoma 29 | 2,716
non-small cell lung cancer 29 | 2,890
pancreatic cancer 28 | 2,398
Cancer 26 | 2,499
Pick disease 26 | 1,894
interstitial cystitis 25 | 2,312
pituitary cancer 23 | 1,972
ulcerative colitis 21 | 1,819
ductal carcinoma in situ 20 | 1,745
breast carcinoma 19 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
colon cancer 17 | 1,478
cystic fibrosis 17 | 1,696
primary pancreatic ductal adenocarcinoma 16 | 1,109
adrenocortical carcinoma 15 | 1,428
group 4 medulloblastoma 15 | 1,855
Intellectual disability 14 | 1,016
acute myeloid leukemia 14 | 783
acute quadriplegic myopathy 14 | 1,158
tuberculosis 14 | 2,010
Liver Cirrhosis, Experimental 12 | 769
Schizophrenia 12 | 1,160
diabetes mellitus 12 | 1,728
medulloblastoma 12 | 720
pediatric high grade glioma 12 | 1,064
Bipolar Disorder 11 | 666
hereditary spastic paraplegia 11 | 318
spina bifida 11 | 1,074
Autosomal recessive predisposition 10 | 1,442
Duchenne muscular dystrophy 10 | 601
Hypertension 10 | 396
Multiple myeloma 10 | 1,332
active ulcerative colitis 10 | 764
aldosterone-producing adenoma 10 | 665
astrocytoma 10 | 1,146
fibroadenoma 10 | 559
Down syndrome 9 | 499
Endometrial cancer 9 | 311
Liver cancer 9 | 604
Osteoporosis 9 | 363
Rheumatoid arthritis 9 | 1,191
dermatomyositis 9 | 966
esophageal adenocarcinoma 9 | 737
Dull intelligence 8 | 645
Low intelligence 8 | 645
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Waldenstrons macroglobulinemia 8 | 765
cutaneous lupus erythematosus 8 | 1,057
gastric carcinoma 8 | 807
Cognitive delay 7 | 608
Epilepsy 7 | 792
Global developmental delay 7 | 608
Heart disease 7 | 306
Mental and motor retardation 7 | 608
Polycystic ovary syndrome 7 | 360
Skin cancer 7 | 469
juvenile dermatomyositis 7 | 1,187
mucosa-associated lymphoid tissue lymphoma 7 | 484
urothelial carcinoma 7 | 318
Breast Neoplasms 6 | 445
Heart failure 6 | 162
Muscle hypotonia 6 | 571
Neoplasm Metastasis 6 | 168
Obesity 6 | 678
Prostatic Neoplasms 6 | 495
active Crohn's disease 6 | 922
hepatocellular carcinoma 6 | 547
progressive supranuclear palsy 6 | 676
Crohn's disease 5 | 321
Glaucoma 5 | 239
Vascular disease 5 | 319
nephrosclerosis 5 | 333
primary Sjogren syndrome 5 | 735

Tissue

Digestive Tract 124 | 17,369
Endocrine System 124 | 18,159
Female tissues 124 | 17,400
Male tissues 123 | 17,142
Nervous System 122 | 16,725
Skin and soft tissues 122 | 17,230
Liver and Pancreas 121 | 16,750
Respiratory system 121 | 16,393
Urinary Tract 121 | 16,678
Blood and immune system 119 | 16,909
Cardiovascular System 115 | 15,192

Target Family

Non-IDG 84 | 12,091
Enzyme 17 | 4,145
Kinase 10 | 634
Ion Channel 7 | 344
Transporter 4 | 473
GPCR 3 | 408

GO Process

protein localization to plasma... 125 | 125
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Protein crumbs homolog 3 CRB3 Tbio Non-IDG -1.22596 16.1 79
Ras-related protein Rab-40A RAB40A Tdark Non-IDG -0.72564 4.56 104
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Src kinase-associated phosphoprotein 1 SKAP1 Tbio Enzyme -1.31527 25.2 175
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Dipeptidyl aminopeptidase-like protein 6 DPP6 Tbio Enzyme -2.06587 114.8 131
E3 ubiquitin-protein ligase SMURF1 SMURF1 Tbio Enzyme -1.95365 89.3 331
Unconventional myosin-Va MYO5A Tbio Non-IDG -1.77097 54.9 83
Tetraspanin-5 TSPAN5 Tbio Non-IDG -0.83620 6.55 126