Development Level

Tbio 24 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to t... 2 | 278
increased heart rate variabili... 2 | 7
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41

Disease

Carcinoma 23 | 11,493
osteosarcoma 22 | 7,950
ovarian cancer 21 | 8,520
Cancer 15 | 2,499
lung cancer 14 | 4,740
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 12 | 5,112
medulloblastoma, large-cell 12 | 6,241
psoriasis 12 | 6,694
ependymoma 10 | 4,679
malignant mesothelioma 10 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pancreatic cancer 9 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Breast cancer 8 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
primitive neuroectodermal tumor 7 | 3,035
Cleft Palate 6 | 271
Dull intelligence 6 | 645
Hypoplastic mandible condyle 6 | 275
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Low intelligence 6 | 645
Mandibular hypoplasia 6 | 275
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Micrognathism 6 | 275
Poor school performance 6 | 645
Short stature 6 | 531
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
tuberculosis 6 | 2,010
Cryptorchidism 5 | 296
Decreased projection of midface 5 | 105
Exophthalmos 5 | 112
Hypotrophic malar bone 5 | 129
Hypotrophic midface 5 | 105
Malar flattening 5 | 129
Midface retrusion 5 | 105
Muscle hypotonia 5 | 571
Orbital separation excessive 5 | 244
Osteoporosis 5 | 363
Skin Neoplasms 5 | 69
Small midface 5 | 105
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Congenital hypoplasia of penis 4 | 176
Craniofacial Abnormalities 4 | 151
Global developmental delay 4 | 608
Hypogonadism 4 | 173
Mammary Neoplasms 4 | 425
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
Muscular dystrophy 4 | 75
Osteoarthritis 4 | 184
Prominent eyes 4 | 96
Prominent globes 4 | 96
Prostatic Neoplasms 4 | 495
Protruding eyes 4 | 96
Respiratory Insufficiency 4 | 132
Respiratory function loss 4 | 121
Sensorineural Hearing Loss (disorder) 4 | 284
Uranostaphyloschisis 4 | 167
astrocytic glioma 4 | 2,597
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
primary Sjogren syndrome 4 | 735
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Broad flat nasal bridge 3 | 236
Curvature of spine 3 | 282
Failure to gain weight 3 | 365
Nasal bridge wide 3 | 236
Pediatric failure to thrive 3 | 365
Strabismus 3 | 270
Syndactyly of the toes 3 | 45
Synostosis 3 | 15
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Blood and immune system 30 | 16,909
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 6 | 1,400
Enzyme 5 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634
Transporter 1 | 473

GO Process

protein localization to nucleu... 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prelamin-A/C LMNA Tbio Non-IDG -3.03952 1089.9 1005
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.41690 2313.9 1252
Exportin-1 XPO1 Tbio Non-IDG -3.14385 1273.6 200
Calreticulin CALR Tbio Non-IDG -3.19563 1544.2 778
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.98303 874.8 508
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Zinc finger and BTB domain-containing protein 16 ZBTB16 Tbio Transcription Factor -2.31797 210.0 275
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
ATP-binding cassette sub-family A member 7 ABCA7 Tbio Transporter -2.20287 157.0 138