Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
edema 1 | 59
embryonic lethality prior to o... 1 | 239
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 5 | 8,520
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Carcinoma 3 | 11,493
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Cognitive delay 2 | 608
Downward slant of palpebral fissure 2 | 158
Global developmental delay 2 | 608
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
Anxiety 1 | 136
Big calvaria 1 | 147
Bilateral fifth finger clinodactyly 1 | 110
Blepharoptosis 1 | 231
Brachycephaly 1 | 88
Breast Neoplasms 1 | 445
Broad cranium shape 1 | 88
Chronic otitis media 1 | 52
Conn's syndrome 1 | 22
Curvature of little finger 1 | 110
Decreased antibody level in blood 1 | 35
Decreased tendon reflex 1 | 122
Down syndrome 1 | 499
Electroencephalogram abnormal 1 | 101
Elevated hepatic transaminases 1 | 81
Endometrial cancer 1 | 311
Epilepsy 1 | 792
Frontal bossing 1 | 157
Hartnup disease 1 | 13
Hepatic enzyme increased 1 | 81
Hepatitis B 1 | 108
Hepatitis C 1 | 94
High forehead 1 | 102
Hypogammaglobulinemia 1 | 35
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Isovaleric acidemia 1 | 15
Kidney disease 1 | 430
Liver Dysfunction 1 | 99
Liver disease 1 | 237
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Long narrow head 1 | 75
Lymphopenia 1 | 67
Malaria 1 | 160
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Orofacial cleft 1 | 54
Pneumonia 1 | 174
Polycystic ovary syndrome 1 | 360
Prenatal onset 1 | 139
Purpura 1 | 43
Recurrent respiratory infections 1 | 141
Stereotyped Behavior 1 | 37
Stereotypic Movement Disorder 1 | 42
Subclinical abnormal liver function tests 1 | 81
Tall forehead 1 | 102
Transaminases increased 1 | 81
Turridolichocephaly 1 | 75
Waldenstrons macroglobulinemia 1 | 765
Wide skull shape 1 | 88
Zellweger syndrome 1 | 37
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
ear infection chronic 1 | 52
glioblastoma multiforme 1 | 142
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
tuberculosis 1 | 2,010

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 1 | 4,145

GO Process

protein localization to lysoso... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD81 antigen CD81 Tchem Non-IDG -2.77049 534.4 771
KICSTOR complex protein SZT2 SZT2 Tbio Non-IDG -0.87849 6.65 52
KICSTOR complex protein C12orf66 C12orf66 Tbio Non-IDG 0.65 0.20 7
SH3 domain-binding protein 4 SH3BP4 Tbio Non-IDG -0.65493 4.55 143
Ragulator complex protein LAMTOR5 LAMTOR5 Tbio Non-IDG -2.24915 162.8 99
Ragulator complex protein LAMTOR4 LAMTOR4 Tdark Non-IDG -0.19564 1.23 34
KICSTOR complex protein kaptin KPTN Tbio Non-IDG -1.45875 26.8 153
E3 ubiquitin-protein ligase RNF128 RNF128 Tbio Enzyme -1.39143 23.7 116