Development Level

Tbio 14 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
decreased bone mineral density 2 | 126
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal eye pigmentation 1 | 3
abnormal heart looping 1 | 5
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 15 | 11,493
ovarian cancer 13 | 8,520
group 3 medulloblastoma 11 | 4,104
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
psoriasis 8 | 6,694
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Schizophrenia 4 | 1,160
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Dull intelligence 3 | 645
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephaly 3 | 166
Poor school performance 3 | 645
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
nasopharyngeal carcinoma 3 | 1,058
Amyotrophic lateral sclerosis 2 | 451
Bipolar Disorder 2 | 666
Ciliopathy 2 | 71
Cognitive delay 2 | 608
Congenital hypoplasia of penis 2 | 176
Endometriosis 2 | 540
Global developmental delay 2 | 608
Joubert syndrome 2 | 66
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 2 | 16
Major Depressive Disorder 2 | 301
Mental and motor retardation 2 | 608
Nystagmus 2 | 317
Pick disease 2 | 1,894
Polydactyly 2 | 107
Rheumatoid arthritis 2 | 1,191
Severe mental retardation (I.Q. 20-34) 2 | 99
Short stature 2 | 531
Small head 2 | 374
Unipolar Depression 2 | 250
Upward slant of palpebral fissure 2 | 75
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Abnormality of epiphysis morphology 1 | 39
Abnormality of hair consistency 1 | 5
Abnormality of hair curl pattern 1 | 5
Abnormality of hair texture 1 | 5
Abnormality of hair volume 1 | 5
Abnormality of the metaphyses 1 | 48
Agranulocytosis 1 | 6
Autosomal recessive malignant osteopetrosis 1 | 4
Autosomal recessive nonsyndromic deafness 48 1 | 1
Blister of skin 1 | 54
Carcinoma of colon 1 | 32
Chromosome 15q24 deletion syndrome 1 | 12
Decreased bone mineral density Z score 1 | 31
Fundus dystrophy 1 | 83
Gastrointestinal Stromal Tumors 1 | 48
Hirsutism 1 | 47
Hypodontia 1 | 81
Hypoplastic feet 1 | 66
Inadequate arch length for tooth size 1 | 45
Left Ventricular Hypertrophy 1 | 47
Motor Skills Disorders 1 | 8
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 8 1 | 1
Peripheral Neuropathy 1 | 134
Renal Cell Carcinoma 1 | 214
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
chronic kidney disease 1 | 90
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Non-IDG 16 | 12,091
Kinase 2 | 634

GO Process

protein localization to centro... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.78486 61.9 82
Protein NEDD1 NEDD1 Tbio Non-IDG -1.40097 25.9 159
Coiled-coil domain-containing protein 14 CCDC14 Tbio Non-IDG 0.38 0.36 32
Protein moonraker KIAA0753 Tdark Non-IDG -2.39179 238.8 13
Microcephalin MCPH1 Tbio Non-IDG -1.96863 109.3 260
SCL-interrupting locus protein STIL Tbio Non-IDG -1.99386 94.6 49