Development Level

Tbio 53 | 11,445
Tdark 7 | 6,588
Tchem 4 | 1,598
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
preweaning lethality, incomple... 4 | 499
decreased vertical activity 3 | 208
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
increased prepulse inhibition 3 | 32
abnormal behavioral response t... 2 | 66
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased mean corpuscular hem... 2 | 50
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
increased body length 2 | 32
increased fasted circulating g... 2 | 76
increased or absent threshold ... 2 | 101
male infertility 2 | 123
prenatal lethality 2 | 28
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver size 1 | 5
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
absent adrenal gland 1 | 2
cataract 1 | 92
cyanosis 1 | 7
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased coping response 1 | 4
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56

Disease

ovarian cancer 42 | 8,520
Carcinoma 40 | 11,493
osteosarcoma 31 | 7,950
medulloblastoma, large-cell 30 | 6,241
glioblastoma 25 | 5,792
ependymoma 24 | 4,679
Astrocytoma, Pilocytic 20 | 3,081
adult high grade glioma 20 | 3,801
atypical teratoid / rhabdoid tumor 20 | 5,112
oligodendroglioma 20 | 2,850
psoriasis 20 | 6,694
lung cancer 19 | 4,740
subependymal giant cell astrocytoma 19 | 2,287
Autosomal recessive predisposition 17 | 1,442
astrocytic glioma 16 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung carcinoma 15 | 2,843
Intellectual disability 14 | 1,016
primitive neuroectodermal tumor 14 | 3,035
Epilepsy 13 | 792
Pick disease 13 | 1,894
Seizures 13 | 596
Breast cancer 12 | 3,578
Kidney cancer 11 | 2,613
group 4 medulloblastoma 11 | 1,855
malignant mesothelioma 11 | 3,232
pancreatic cancer 11 | 2,398
Cancer 10 | 2,499
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
Neurodegenerative disease 9 | 414
Paraplegia 9 | 74
Schizophrenia 9 | 1,160
Small head 9 | 374
colon cancer 9 | 1,478
lung adenocarcinoma 9 | 2,716
ulcerative colitis 9 | 1,819
Hyperreflexia 8 | 209
breast carcinoma 8 | 1,638
interstitial cystitis 8 | 2,312
non-small cell lung cancer 8 | 2,890
pituitary cancer 8 | 1,972
Babinski Reflex 7 | 100
Dilated ventricles (finding) 7 | 121
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Short stature 7 | 531
invasive ductal carcinoma 7 | 2,951
tuberculosis 7 | 2,010
Hypertensive disease 6 | 292
Melanoma 6 | 711
Microcephaly 6 | 166
Prenatal onset 6 | 139
Severe mental retardation (I.Q. 20-34) 6 | 99
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Acquired immunodeficiency syndrome 5 | 197
Anxiety 5 | 136
Anxiety disease 5 | 113
Attention deficit hyperactivity disorder 5 | 278
Autistic Disorder 5 | 364
Depressive disorder 5 | 409
Huntington's disease 5 | 76
Hydrocephalus 5 | 152
Hypertension 5 | 396
Liver cancer 5 | 604
Macrostomia 5 | 72
Nystagmus 5 | 317
Rheumatoid arthritis 5 | 1,191
Skin cancer 5 | 469
Spastic Paraplegia 5 | 42
hereditary spastic paraplegia 5 | 318
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Cerebral atrophy 4 | 178
Endometrial cancer 4 | 311
Failure to gain weight 4 | 365
Highly variable clinical phenotype 4 | 150
Highly variable phenotype and severity 4 | 150
Male infertility 4 | 206
Muscle Spasticity 4 | 195
Pediatric failure to thrive 4 | 365
Phenotypic variability 4 | 150
Progressive disorder 4 | 142
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
glioblastoma multiforme 4 | 142
posterior fossa group B ependymoma 4 | 416
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 65 | 18,159
Blood and immune system 64 | 16,909
Digestive Tract 64 | 17,369
Female tissues 64 | 17,400
Skin and soft tissues 64 | 17,230
Male tissues 63 | 17,142
Nervous System 63 | 16,725
Liver and Pancreas 62 | 16,750
Urinary Tract 62 | 16,678
Respiratory system 61 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 45 | 12,091
Enzyme 11 | 4,145
Ion Channel 4 | 344
Kinase 2 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

protein localization 67 | 67
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent RNA helicase DDX42 DDX42 Tbio Enzyme -1.10894 13.3 60
Vacuolar protein sorting-associated protein 13A VPS13A Tbio Non-IDG -2.19966 172.3 22
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
MARVEL domain-containing protein 1 MARVELD1 Tbio Non-IDG -1.58692 39.1 60
Plasmolipin PLLP Tbio Ion Channel -1.58286 39.3 74
Centrosomal protein of 128 kDa CEP128 Tdark Non-IDG 0.18 0.11 79
Arrestin domain-containing protein 4 ARRDC4 Tdark Non-IDG -0.57316 3.44 87
Codanin-1 CDAN1 Tbio Non-IDG -2.03633 107.9 69
Kinesin heavy chain isoform 5A KIF5A Tbio Non-IDG -1.69131 48.4 170
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69