Development Level

Tbio 22 | 11,445
Tchem 18 | 1,598
Tclin 6 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
abnormal lung morphology 2 | 26
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
enlarged heart 2 | 210
male infertility 2 | 123
small testis 2 | 58
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased lymphocyte cell numb... 1 | 83
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
pale yolk sac 1 | 25
pallor 1 | 34
small seminal vesicle 1 | 10
thrombocytopenia 1 | 56

Disease

Cancer 37 | 2,499
Carcinoma 29 | 11,493
psoriasis 27 | 6,694
ovarian cancer 25 | 8,520
osteosarcoma 24 | 7,950
lung cancer 22 | 4,740
glioblastoma 20 | 5,792
medulloblastoma, large-cell 18 | 6,241
diabetes mellitus 17 | 1,728
atypical teratoid / rhabdoid tumor 16 | 5,112
Breast cancer 15 | 3,578
malignant mesothelioma 15 | 3,232
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
tuberculosis 13 | 2,010
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
Obesity 12 | 678
ependymoma 12 | 4,679
invasive ductal carcinoma 12 | 2,951
lung carcinoma 12 | 2,843
non-small cell lung cancer 12 | 2,890
Alzheimer's disease 11 | 658
Kidney disease 11 | 430
Multiple Sclerosis 11 | 540
adult high grade glioma 11 | 3,801
cystic fibrosis 11 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
juvenile dermatomyositis 11 | 1,187
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Autosomal recessive predisposition 10 | 1,442
Endometriosis 10 | 540
Prostatic Neoplasms 10 | 495
adrenocortical carcinoma 10 | 1,428
lung adenocarcinoma 10 | 2,716
pancreatic cancer 10 | 2,398
Asthma 9 | 385
Atherosclerosis 9 | 291
Bipolar Disorder 9 | 666
Coronary artery disease 9 | 268
Liver Cirrhosis, Experimental 9 | 769
Lung Neoplasms 9 | 232
Neoplasm Invasiveness 9 | 161
Vascular disease 9 | 319
ductal carcinoma in situ 9 | 1,745
Astrocytoma, Pilocytic 8 | 3,081
Cerebrovascular disease 8 | 238
Hyperglycemia 8 | 137
Hypersensitivity reaction type II disease 8 | 253
Hypertension 8 | 396
Hypertensive disease 8 | 292
Kidney cancer 8 | 2,613
Lung disease 8 | 142
Reperfusion Injury 8 | 86
Schizophrenia 8 | 1,160
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
Arthritis 7 | 290
Carcinoma, Hepatocellular 7 | 228
Depressive disorder 7 | 409
Dull intelligence 7 | 645
Epilepsy 7 | 792
Heart disease 7 | 306
Inflammation 7 | 120
Inflammatory bowel disease 7 | 151
Intellectual disability 7 | 1,016
Liver carcinoma 7 | 240
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Myocardial Ischemia 7 | 169
Neoplasm Metastasis 7 | 168
Pancreatic Neoplasms 7 | 85
Parkinson's disease 7 | 392
Poor school performance 7 | 645
Pulmonary Fibrosis 7 | 106
Renal Cell Carcinoma 7 | 214
Seizures 7 | 596
acute quadriplegic myopathy 7 | 1,158
primitive neuroectodermal tumor 7 | 3,035
sarcoidosis 7 | 370
subependymal giant cell astrocytoma 7 | 2,287
Adenoma 6 | 167
Lipid metabolism disorder 6 | 114
Major Depressive Disorder 6 | 301
Malaria 6 | 160
Myopathy 6 | 185
Myopia 6 | 176
Pancreatic Neoplasm 6 | 85
Pick disease 6 | 1,894
Stomach Neoplasms 6 | 300
Unipolar Depression 6 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
dermatomyositis 6 | 966
hepatocellular carcinoma 6 | 547
interstitial cystitis 6 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962

Tissue

Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Urinary Tract 46 | 16,678
Blood and immune system 45 | 16,909
Digestive Tract 45 | 17,369
Liver and Pancreas 45 | 16,750
Respiratory system 45 | 16,393
Skin and soft tissues 45 | 17,230
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 15 | 12,091
Kinase 13 | 634
Enzyme 8 | 4,145
Transcription Factor 7 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Process

protein kinase B signaling 46 | 46
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
E3 ubiquitin-protein ligase makorin-1 MKRN1 Tbio Enzyme -0.96099 16.4 225
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Tyrosine-protein kinase Mer MERTK Tchem Kinase -2.27276 199.1 609
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Forkhead box protein O4 FOXO4 Tbio Transcription Factor -2.43923 278.0 720
mRNA decay activator protein ZFP36L1 ZFP36L1 Tbio Non-IDG -1.51339 38.6 285