Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
female infertility 1 | 60
increased fasted circulating g... 1 | 76
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 9 | 11,493
diabetes mellitus 5 | 1,728
glioblastoma 5 | 5,792
osteosarcoma 5 | 7,950
Breast cancer 4 | 3,578
Cancer 4 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Becker muscular dystrophy 3 | 191
Hyperglycemia 3 | 137
Hypertensive disease 3 | 292
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Cholestasis 2 | 155
Congenital nystagmus 2 | 26
DOID:2627 2 | 94
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Heart disease 2 | 306
Heart failure 2 | 162
Hyperinsulinism 2 | 133
Hypertension 2 | 396
Infantile onset 2 | 238
Motor delay 2 | 147
Neurofibromatosis 2 | 40
No development of motor milestones 2 | 147
Obesity 2 | 678
Tachycardia 2 | 43
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
group 3 medulloblastoma 2 | 4,104
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
Aberrant Crypt Foci 1 | 3
Abnormality of position of teeth 1 | 8
Acromicric Dysplasia 1 | 5
Alcohol abuse 1 | 50
Aneurysm of ascending aorta 1 | 5
Aortic Aneurysm, Thoracic 1 | 8
Aortic valve stenosis 1 | 28
Autonomic neuropathy 1 | 22
Broad ribs 1 | 12
Bullet vertebral body 1 | 17
Coma 1 | 5
Drug-induced depressive state 1 | 14
Eyebrow abnormalities 1 | 12
Heart murmur 1 | 5
Hyperlipidemias 1 | 17
Hypothermia 1 | 12
Hypothermia, natural 1 | 17
Lipoatrophy 1 | 19
Marfan Syndrome 1 | 15
Meconium aspiration syndrome 1 | 4
Misalignment of teeth 1 | 8
Multiple Endocrine Neoplasia Type 1 1 | 29
Ovoid vertebral bodies 1 | 17
Premature osteoarthritis 1 | 6
Protrusio acetabuli 1 | 7
Severe myopia 1 | 22
Shallow anterior chamber of eye 1 | 4
Short phalanx of finger 1 | 32
Sinus Tachycardia 1 | 4
Spade-like hand 1 | 16
Spasm 1 | 6
Spondylolisthesis 1 | 22
Stiff skin 1 | 3
Stomach disease 1 | 8
Sudden death 1 | 16
Tachycardia, Sinus 1 | 2
Thoracic aortic aneurysm 1 | 15
Tobacco Use Disorder 1 | 12
Tricuspid valve insufficiency 1 | 14
Zollinger-Ellison syndrome 1 | 18

Tissue

Endocrine System 11 | 18,159
Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Respiratory system 9 | 16,393
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 9 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

protein kinase A signaling 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 11 homolog TCP11 Tbio Non-IDG -1.26152 18.0 80
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Titin TTN Tbio Kinase -3.24415 1743.0 123
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.40524 27.4 73
Radixin RDX Tbio Non-IDG -2.47844 221.4 333
Maestro heat-like repeat-containing protein family member 2B MROH2B Tdark Non-IDG 0.00000 1.00 17
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Glucagon GCG Tchem Non-IDG -4.23329 17114.4 1097
Plastin-2 LCP1 Tbio Non-IDG -2.22829 176.7 267