Development Level

Tbio 9 | 11,445

IMPC Phenotype

enlarged spleen 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Abnormal skeletal development 9 | 60
Abnormality of metabolism/homeostasis 9 | 134
Abnormality of retinal pigmentation 9 | 111
Autosomal recessive predisposition 9 | 1,442
Blepharoptosis 9 | 231
Cataract 9 | 297
Cerebellar Ataxia 9 | 304
Concave bridge of nose 9 | 195
Depressed nasal bridge 9 | 195
Depressed nasal root/bridge 9 | 195
Developmental regression 9 | 95
Difficulties with night vision 9 | 87
Elevated levels of phytanic acid 9 | 15
Epilepsy 9 | 792
Flat face 9 | 52
Hypoplastic mandible condyle 9 | 275
Infantile Refsum disease 9 | 23
Lens Opacities 9 | 231
Loss of developmental milestones 9 | 95
Low Vision 9 | 174
Mandibular hypoplasia 9 | 275
Mental deterioration in childhood 9 | 95
Micrognathism 9 | 275
Muscle Spasticity 9 | 195
Muscle hypotonia 9 | 571
Neurodevelopmental regression 9 | 95
Night Blindness 9 | 101
Nystagmus 9 | 317
Osteochondrodysplasias 9 | 72
Peroxisomal disease 9 | 22
Psychomotor regression 9 | 95
Psychomotor regression beginning in infancy 9 | 95
Psychomotor regression in infants 9 | 95
Psychomotor regression, progressive 9 | 95
Respiratory Insufficiency 9 | 132
Respiratory function loss 9 | 121
Retinal pigment epithelial abnormality 9 | 111
Retinitis Pigmentosa 9 | 226
Seizures 9 | 596
Sensorineural Hearing Loss (disorder) 9 | 284
Small head 9 | 374
Stippled epiphyses 9 | 28
Upward slant of palpebral fissure 9 | 75
Visual Impairment 9 | 174
Zellweger syndrome 9 | 37
Abnormal behavior 8 | 52
Addison Disease 8 | 18
Adrenal cortical hypofunction 8 | 23
Adrenoleukodystrophy, Neonatal 8 | 13
Anteverted nostril 8 | 191
Bilateral single transverse palmar creases 8 | 34
Broad flat nasal bridge 8 | 236
Byzanthine arch palate 8 | 194
Clouding of corneal stroma 8 | 50
Congenital Epicanthus 8 | 177
Corneal Opacity 8 | 53
Death in early childhood 8 | 82
Death in infancy 8 | 82
Decreased to absent deep tendon reflexes 8 | 42
Electroencephalogram abnormal 8 | 101
Embryotoxon 8 | 28
Failure to gain weight 8 | 365
Flat occiput 8 | 26
Global developmental delay, severe 8 | 47
Hepatomegaly 8 | 285
High forehead 8 | 102
Hydronephrosis 8 | 89
Hyperreflexia 8 | 209
Hypertrophy of clitoris 8 | 40
Hypotonia, severe 8 | 33
Icterus 8 | 82
Impaired cognition 8 | 96
Infantile Refsum Disease (disorder) 8 | 13
Liver Failure 8 | 73
Liver diseases 8 | 87
Long narrow head 8 | 75
Malabsorption 8 | 82
Malformations of Cortical Development, Group II 8 | 31
Malformed pinnae 8 | 37
Mental impairment 8 | 95
Movement Disorders 8 | 55
Muscle weakness, progressive 8 | 22
Nasal bridge wide 8 | 236
Pediatric failure to thrive 8 | 365
Penile hypospadias 8 | 106
Polymicrogyria 8 | 48
Posterior embryotoxon 8 | 28
Premature Birth 8 | 77
Premature birth of newborn 8 | 67
Profound global developmental delay 8 | 17
Psychomotor retardation, profound 8 | 17
Pyloric Stenosis 8 | 47
Severe psychomotor retardation 8 | 47
Strabismus 8 | 270
Tall forehead 8 | 102
Underdeveloped brows 8 | 38
Underdeveloped supraorbital ridges 8 | 38
Very long chain fatty acid accumulation 8 | 13
Visual field constriction 8 | 36
Wide anterior fontanel 8 | 44

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145

GO Process

protein import into peroxisome... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.77059 5.43 107
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Peroxisomal membrane protein PEX14 PEX14 Tbio Non-IDG -1.56143 37.1 205
Peroxisome assembly protein 26 PEX26 Tbio Non-IDG -1.04829 11.8 85
Peroxisome assembly protein 12 PEX12 Tbio Non-IDG -1.33622 21.4 101
Peroxisomal targeting signal 2 receptor PEX7 Tbio Non-IDG -1.60893 39.4 103
Peroxisome biogenesis factor 10 PEX10 Tbio Non-IDG -1.41345 23.8 102