Development Level

Tbio 39 | 11,651
Tdark 11 | 6,593
Tchem 3 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal embryo size 3 | 220
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
cataract 2 | 92
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal retinal vasculature m... 1 | 27
cleft palate 1 | 8
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating lipase l... 1 | 3
decreased circulating magnesiu... 1 | 13
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hypoactivity 1 | 132
increased circulating calcium ... 1 | 34
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
thrombocytopenia 1 | 56

Disease

Carcinoma 40 | 11,493
ovarian cancer 32 | 8,519
osteosarcoma 26 | 7,950
lung cancer 25 | 4,740
group 3 medulloblastoma 22 | 4,104
glioblastoma 19 | 5,792
medulloblastoma, large-cell 19 | 6,241
psoriasis 17 | 6,694
atypical teratoid / rhabdoid tumor 15 | 5,112
Kidney cancer 14 | 2,613
ependymoma 14 | 4,679
Breast cancer 12 | 3,577
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
Multiple myeloma 11 | 1,332
Cancer 10 | 2,499
astrocytoma 10 | 1,146
dermatomyositis 10 | 966
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,290
astrocytic glioma 9 | 2,597
lung adenocarcinoma 9 | 2,716
Waldenstrons macroglobulinemia 8 | 765
colon cancer 8 | 1,478
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
Astrocytoma, Pilocytic 7 | 3,081
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
acute quadriplegic myopathy 7 | 1,158
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,954
Atopic dermatitis 6 | 952
HIV Infections 6 | 102
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
juvenile dermatomyositis 6 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
Liver cancer 5 | 604
invasive ductal carcinoma 5 | 2,950
nasopharyngeal carcinoma 5 | 1,058
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Leukemia, Myelocytic, Acute 4 | 120
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
subependymal giant cell astrocytoma 4 | 2,287
Attention deficit hyperactivity disorder 3 | 278
Autosomal recessive predisposition 3 | 1,442
Cognitive delay 3 | 608
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Global developmental delay 3 | 608
Leukemia, Myeloid, Acute 3 | 105
Mental and motor retardation 3 | 608
Multiple Sclerosis 3 | 540
Optic Atrophy 3 | 242
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,695
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
non-small cell lung carcinoma 3 | 317
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Animal Mammary Neoplasms 2 | 136
Arthritis, Rheumatoid 2 | 174
Autistic Disorder 2 | 364
Breast Neoplasms 2 | 445
Colonic Neoplasms 2 | 142
Curvature of spine 2 | 282
Depressive disorder 2 | 409
Disease Progression 2 | 136
Epilepsy 2 | 792
Gaucher disease type 1 2 | 180
Infantile onset 2 | 238
Inflammation 2 | 120
Kidney disease 2 | 430
Leukemia 2 | 104
Melanoma 2 | 711
Muscle Spasticity 2 | 195
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Recurrent respiratory infections 2 | 141
Seizures 2 | 596
Specific learning disability 2 | 47
Stomach Neoplasms 2 | 300
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,637
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
lung carcinoma 2 | 2,843
pancreatic carcinoma 2 | 562
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,108
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Endocrine System 52 | 18,159
Blood and immune system 49 | 16,909
Digestive Tract 49 | 17,369
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Respiratory system 49 | 16,393
Skin and soft tissues 49 | 17,230
Urinary Tract 49 | 16,678
Nervous System 47 | 16,725
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 8 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

protein import into nucleus 54 | 54
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
POM121-like protein 2 POM121L2 Tdark Non-IDG 0.40 0.40 5
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
Nuclear pore complex protein Nup50 NUP50 Tbio Non-IDG -1.18445 15.9 270
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.69756 4.39 42
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.80390 62.5 241
Ran-binding protein 3-like RANBP3L Tdark Non-IDG -0.25756 2.29 69
Nuclear pore complex protein Nup133 NUP133 Tbio Non-IDG -1.36479 22.8 72
RPA-interacting protein RPAIN Tbio Non-IDG -1.41218 24.1 153