Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal tooth morphology 1 | 24
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
increased aggression 1 | 4
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134

Disease

invasive ductal carcinoma 4 | 2,951
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
acute quadriplegic myopathy 3 | 1,158
glioblastoma 3 | 5,792
juvenile dermatomyositis 3 | 1,187
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer Disease 2 | 83
Alzheimer's disease 2 | 658
Amyloidosis 2 | 67
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Chemical and Drug Induced Liver Injury 2 | 195
Dementia 2 | 175
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Familial hyperlipidemia 2 | 6
Kidney disease 2 | 430
Schizophrenia 2 | 1,160
Seizures 2 | 596
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pediatric high grade glioma 2 | 1,064
ulcerative colitis 2 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Acute kidney injury 1 | 70
Adenocarcinoma 1 | 122
Adverse reaction to drug 1 | 61
Age related macular degeneration 1 | 72
Alcohol abuse 1 | 50
Aphasia 1 | 26
Atrophic 1 | 10
Atrophy 1 | 10
Blepharitis 1 | 23
Brain disease 1 | 96
Cardiomegaly 1 | 116
Carotid Artery Diseases 1 | 11
Carotid stenosis 1 | 5
Cellulitis of eyelid 1 | 17
Cerebral amyloid angiopathy 1 | 13
Coronary Disease 1 | 25
Danon disease 1 | 8
Decreased platelet count 1 | 111
Delirium 1 | 10
Drug-Related Side Effects and Adverse Reactions 1 | 62
Dyslipidemias 1 | 27
EMG: myopathic abnormalities 1 | 22
Edema 1 | 81
Emphysema 1 | 12
Fuchs' endothelial dystrophy 1 | 24
Gaucher disease type 3 1 | 67
Hearing Loss 1 | 17
Hepatolenticular Degeneration 1 | 24
High density lipoprotein decreased 1 | 10
Hypercholesterolemia, Familial 1 | 23
Hyperglycemia 1 | 137
Hyperlipidemia 1 | 43
Hyperlipoproteinemia Type II 1 | 12
Hypertriglyceridemia result 1 | 37
Hypoalphalipoproteinemias 1 | 10
Infiltrate of lung 1 | 17
Iris disease 1 | 10
Liver disease 1 | 237
Long tract signs 1 | 3
Lupus Erythematosus, Systemic 1 | 67
Lysosomal storage disease 1 | 10
Macular Degeneration, Age-Related, 1 1 | 9
Macular degeneration 1 | 65
Myocardial Infarction 1 | 151
Nerve Degeneration 1 | 121
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Pancreatitis 1 | 123
Panic disorder 1 | 61
Parkinsonian Disorders 1 | 56
Pathological accumulation of air in tissues 1 | 10
Renal glomerular disease 1 | 12
Serum cholesterol raised 1 | 22
Steatohepatitis 1 | 44
Subcutaneous nodule 1 | 53
Thrombocytopenia 1 | 197
Ureteral obstruction 1 | 33
X-linked dominant 1 | 57
chronic kidney disease 1 | 90

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 5 | 12,091

GO Process

protein import 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-33 SNX33 Tbio Non-IDG -0.49386 3.94 99
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.82315 79.6 104
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.57929 343.7 905
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Clusterin CLU Tbio Non-IDG -3.28651 2016.4 826