Development Level

Tbio 47 | 11,651
Tchem 13 | 1,388
Tclin 11 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal behavior 2 | 298
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 162
abnormal incisor morphology 1 | 4
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased food intake 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased startle reflex 1 | 112
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

Carcinoma 45 | 11,493
ovarian cancer 43 | 8,520
psoriasis 41 | 6,694
osteosarcoma 39 | 7,950
lung cancer 30 | 4,740
medulloblastoma, large-cell 27 | 6,241
Cancer 25 | 2,499
glioblastoma 23 | 5,792
invasive ductal carcinoma 23 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
interstitial cystitis 22 | 2,312
atypical teratoid / rhabdoid tumor 20 | 5,112
malignant mesothelioma 20 | 3,232
Breast cancer 18 | 3,578
ependymoma 18 | 4,679
oligodendroglioma 18 | 2,850
group 3 medulloblastoma 17 | 4,104
lung adenocarcinoma 17 | 2,716
pancreatic cancer 17 | 2,398
Autosomal recessive predisposition 16 | 1,442
diabetes mellitus 16 | 1,728
non-small cell lung cancer 16 | 2,890
Astrocytoma, Pilocytic 15 | 3,081
adult high grade glioma 14 | 3,801
breast carcinoma 14 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
lung carcinoma 14 | 2,843
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
tuberculosis 13 | 2,010
ulcerative colitis 13 | 1,819
Kidney cancer 12 | 2,613
adrenocortical carcinoma 12 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
pituitary cancer 12 | 1,972
primitive neuroectodermal tumor 12 | 3,035
astrocytic glioma 11 | 2,597
astrocytoma 11 | 1,146
subependymal giant cell astrocytoma 11 | 2,287
Schizophrenia 10 | 1,160
Obesity 9 | 678
cutaneous lupus erythematosus 9 | 1,057
dermatomyositis 9 | 966
Adenocarcinoma of lung 8 | 142
Kidney disease 8 | 430
Multiple myeloma 8 | 1,332
Pick disease 8 | 1,894
Rheumatoid arthritis 8 | 1,191
acute quadriplegic myopathy 8 | 1,158
gastric cancer 8 | 459
gastric carcinoma 8 | 807
nasopharyngeal carcinoma 8 | 1,058
pediatric high grade glioma 8 | 1,064
Atopic dermatitis 7 | 952
Breast Neoplasms 7 | 445
Carcinoma, Hepatocellular 7 | 228
Hypertension 7 | 396
Liver Cirrhosis, Experimental 7 | 769
Liver carcinoma 7 | 240
Mammary Neoplasms 7 | 425
Muscle hypotonia 7 | 571
Waldenstrons macroglobulinemia 7 | 765
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
esophageal adenocarcinoma 7 | 737
group 4 medulloblastoma 7 | 1,855
primary Sjogren syndrome 7 | 735
Alzheimer's disease 6 | 658
Amyotrophic lateral sclerosis 6 | 451
Anemia 6 | 365
Asthma 6 | 385
Atherosclerosis 6 | 291
Disease Models, Animal 6 | 155
Prostatic Neoplasms 6 | 495
Seizures 6 | 596
acute myeloid leukemia 6 | 783
juvenile dermatomyositis 6 | 1,187
nephrosclerosis 6 | 333
non-small cell lung carcinoma 6 | 317
Colorectal Neoplasms 5 | 243
Down syndrome 5 | 499
Endometrial cancer 5 | 311
Epilepsy 5 | 792
Fever 5 | 138
Heart disease 5 | 306
Highly variable clinical phenotype 5 | 150
Highly variable phenotype and severity 5 | 150
Highly variable phenotype, even within families 5 | 150
Liver cancer 5 | 604
Myocardial Ischemia 5 | 169
Neoplasm Metastasis 5 | 168
Neuropathy 5 | 261
Pain agnosia 5 | 104
Phenotypic variability 5 | 150
Vascular disease 5 | 319
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
hepatocellular carcinoma 5 | 547
Endometriosis 4 | 540
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 72 | 18,159
Nervous System 72 | 16,725
Digestive Tract 71 | 17,369
Liver and Pancreas 71 | 16,750
Skin and soft tissues 71 | 17,230
Blood and immune system 70 | 16,909
Female tissues 70 | 17,400
Male tissues 70 | 17,142
Respiratory system 69 | 16,393
Urinary Tract 69 | 16,678
Cardiovascular System 68 | 15,192

Target Family

Enzyme 41 | 4,145
Non-IDG 15 | 12,091
Ion Channel 9 | 344
Kinase 3 | 634
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400

GO Process

protein homotetramerization 72 | 72
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carbonyl reductase family member 4 CBR4 Tbio Enzyme -1.69083 48.5 128
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.61157 386.3 882
Ubiquitin carboxyl-terminal hydrolase 16 USP16 Tbio Enzyme -0.67094 5.97 248
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.96722 8709.0 274
Long-chain specific acyl-CoA dehydrogenase, mitochondrial ACADL Tbio Enzyme -1.52646 31.4 231
ATPase inhibitor, mitochondrial ATP5IF1 Tbio Enzyme -2.19240 149.7 166
Protein chibby homolog 1 CBY1 Tbio Non-IDG -2.29880 197.7 79
S-adenosylmethionine synthase isoform type-1 MAT1A Tbio Enzyme -2.11527 125.3 167