Development Level

Tbio 128 | 11,445
Tclin 35 | 613
Tchem 29 | 1,598
Tdark 14 | 6,588

Collection

Ion Channel: IDG Consortium (T... 12 | 99

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 8 | 298
preweaning lethality, incomple... 8 | 499
decreased grip strength 5 | 116
hyperactivity 4 | 148
increased mean corpuscular hem... 4 | 96
increased total body fat amoun... 4 | 134
abnormal embryo size 3 | 220
decreased body weight 3 | 161
decreased heart weight 3 | 27
decreased neutrophil cell numb... 3 | 42
increased circulating alkaline... 3 | 122
increased mean corpuscular vol... 3 | 92
abnormal behavioral response t... 2 | 66
abnormal clavicle morphology 2 | 6
abnormal coat appearance 2 | 31
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 135
decreased mean platelet volume 2 | 25
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating LDL chol... 2 | 13
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 66
increased circulating iron lev... 2 | 30
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal cranium morphology 1 | 36
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
brachydactyly 1 | 19
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased threshold for audito... 1 | 26
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged spleen 1 | 41
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
long tibia 1 | 25
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality 1 | 28
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened RR interval 1 | 17
shortened ST segment 1 | 10
small seminal vesicle 1 | 10
small testis 1 | 58
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 126 | 11,493
ovarian cancer 101 | 8,520
osteosarcoma 92 | 7,950
psoriasis 84 | 6,694
medulloblastoma, large-cell 83 | 6,241
glioblastoma 70 | 5,792
lung cancer 63 | 4,740
group 3 medulloblastoma 59 | 4,104
atypical teratoid / rhabdoid tumor 58 | 5,112
ependymoma 58 | 4,679
adult high grade glioma 56 | 3,801
Astrocytoma, Pilocytic 48 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,291
primitive neuroectodermal tumor 45 | 3,035
Breast cancer 43 | 3,578
lung carcinoma 42 | 2,843
malignant mesothelioma 40 | 3,232
Cancer 39 | 2,499
invasive ductal carcinoma 39 | 2,951
Kidney cancer 38 | 2,613
non-small cell lung cancer 38 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
oligodendroglioma 35 | 2,850
Multiple Sclerosis 34 | 540
astrocytic glioma 31 | 2,597
lung adenocarcinoma 31 | 2,716
Autosomal recessive predisposition 30 | 1,442
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
pancreatic cancer 30 | 2,398
ulcerative colitis 30 | 1,819
interstitial cystitis 29 | 2,312
pituitary cancer 29 | 1,972
Pick disease 28 | 1,894
subependymal giant cell astrocytoma 28 | 2,287
Eaton-Lambert syndrome 27 | 40
colon cancer 26 | 1,478
Epilepsy 25 | 792
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
diabetes mellitus 23 | 1,728
ductal carcinoma in situ 21 | 1,745
tuberculosis 21 | 2,010
Schizophrenia 19 | 1,160
adrenocortical carcinoma 19 | 1,428
cystic fibrosis 19 | 1,696
group 4 medulloblastoma 19 | 1,855
Seizures 18 | 596
breast carcinoma 18 | 1,638
Atopic dermatitis 17 | 952
Multiple myeloma 17 | 1,332
active Crohn's disease 16 | 922
primary pancreatic ductal adenocarcinoma 16 | 1,109
Intellectual disability 15 | 1,016
Neurodegenerative disease 15 | 414
Obesity 15 | 678
aldosterone-producing adenoma 15 | 665
cutaneous lupus erythematosus 15 | 1,057
dermatomyositis 15 | 966
acute quadriplegic myopathy 14 | 1,158
gastric carcinoma 14 | 807
spina bifida 14 | 1,074
Cognitive delay 13 | 608
Down syndrome 13 | 499
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Muscle hypotonia 13 | 571
esophageal adenocarcinoma 13 | 737
juvenile dermatomyositis 13 | 1,187
nasopharyngeal carcinoma 13 | 1,058
progressive supranuclear palsy 13 | 676
Bipolar Disorder 12 | 666
Depressive disorder 12 | 409
Liver Cirrhosis, Experimental 12 | 769
Rheumatoid arthritis 12 | 1,191
Short stature 12 | 531
astrocytoma 12 | 1,146
non primary Sjogren syndrome sicca 12 | 891
Heart disease 11 | 306
Hepatomegaly 11 | 285
Waldenstrons macroglobulinemia 11 | 765
Alzheimer's disease 10 | 658
Amyotrophic lateral sclerosis 10 | 451
Cataract 10 | 297
Cerebellar Ataxia 10 | 304
Small head 10 | 374
medulloblastoma 10 | 720
pediatric high grade glioma 10 | 1,064
Dull intelligence 9 | 645
Failure to gain weight 9 | 365
Hypertension 9 | 396
Lens Opacities 9 | 231
Low intelligence 9 | 645
Mental Depression 9 | 333
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Nystagmus 9 | 317
Pediatric failure to thrive 9 | 365
Poor school performance 9 | 645
fibroadenoma 9 | 559
hepatocellular carcinoma 9 | 547
mucosa-associated lymphoid tissue lymphoma 9 | 484

Tissue

Endocrine System 199 | 18,159
Digestive Tract 198 | 17,369
Nervous System 196 | 16,725
Skin and soft tissues 196 | 17,230
Female tissues 195 | 17,400
Liver and Pancreas 192 | 16,750
Male tissues 192 | 17,142
Urinary Tract 192 | 16,678
Blood and immune system 187 | 16,909
Respiratory system 185 | 16,393
Cardiovascular System 174 | 15,192

Target Family

Non-IDG 128 | 12,091
Ion Channel 36 | 344
Enzyme 27 | 4,145
Transporter 6 | 473
Kinase 4 | 634
Transcription Factor 4 | 1,400
Epigenetic 1 | 242

GO Process

protein homooligomerization 206 | 206
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Centrosomal protein of 57 kDa CEP57 Tbio Non-IDG -0.98216 11.8 177
BTB/POZ domain-containing protein KCTD5 KCTD5 Tbio Non-IDG -1.70628 50.2 52
Potassium voltage-gated channel subfamily A member 7 KCNA7 Tclin Ion Channel -0.87978 7.43 59
Nucleus accumbens-associated protein 1 NACC1 Tbio Non-IDG -1.20525 18.5 218
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Derlin-1 DERL1 Tbio Non-IDG -1.88253 69.7 178
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205