Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 1 | 298
decreased granulocyte number 1 | 6
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged uterus 1 | 11
hydrometra 1 | 53
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 7 | 11,493
osteosarcoma 7 | 7,950
group 3 medulloblastoma 5 | 4,104
ovarian cancer 5 | 8,520
Pick disease 4 | 1,894
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Neurodegenerative disease 3 | 414
Waldenstrons macroglobulinemia 3 | 765
atypical teratoid / rhabdoid tumor 3 | 5,112
non-small cell lung cancer 3 | 2,890
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Alzheimer's disease 2 | 658
Babinski Reflex 2 | 100
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cerebellar Ataxia 2 | 304
Decreased lower limb vibratory sense 2 | 13
Dementia 2 | 175
Depressive disorder 2 | 409
Forgetful 2 | 40
Intellectual disability 2 | 1,016
Memory Loss 2 | 40
Memory impairment 2 | 40
Multiple myeloma 2 | 1,332
Neuropathy 2 | 261
Nystagmus 2 | 317
Optic Atrophy 2 | 242
Paraplegia 2 | 74
Physical aggression 2 | 76
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Social disinhibition 2 | 14
Spastic Paraplegia 2 | 42
Spastic gait 2 | 23
Stereotyped Behavior 2 | 37
Stereotypic Movement Disorder 2 | 42
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
progressive supranuclear palsy 2 | 676
Abnormal brain FDG positron emission tomography 1 | 9
Acute maxillary sinusitis 1 | 2
Agitation 1 | 16
Alexia 1 | 6
Aplasia/Hypoplasia of the lungs 1 | 13
Behavioral variant of frontotemporal dementia 1 | 8
Calvarial defect 1 | 10
Compulsive hoarding 1 | 7
Congenital ectopic pupil 1 | 7
Convex nasal ridge 1 | 37
Cranial defect 1 | 10
Decreased muscle mass 1 | 28
Developmental arithmetic disorder 1 | 8
Difficulty making arithmetical calculations 1 | 8
Downturned corners of mouth 1 | 48
Dysphasia 1 | 23
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Enterocolitis, Necrotizing 1 | 17
Excess nuchal skin 1 | 30
Fasciculation, Tongue 1 | 8
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Frontotemporal cerebral atrophy 1 | 8
Generalized hypotonia 1 | 37
Hammer Toe 1 | 23
Hyperorality 1 | 7
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Langerhans-cell histiocytosis 1 | 12
Mitochondrial DNA depletion syndrome 7 1 | 2
Narrowing of ear canal 1 | 13
Necrotizing Enterocolitis 1 | 17
OPTIC ATROPHY 11 1 | 1
Periventricular cysts 1 | 7
Perrault syndrome 1 | 19
Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 1 1 | 5
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1 1 | 5
Reflex, Ankle, Absent 1 | 8
Repeated speech 1 | 9
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Rieger syndrome 1 | 8
Semantic Dementia 1 | 7
Severe postnatal growth retardation 1 | 16
Shoulder girdle muscle atrophy 1 | 6
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Skull defect 1 | 10
Stenosis of external auditory canal 1 | 13
Warsaw breakage syndrome 1 | 11
Xerostomia 1 | 42

Tissue

Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Enzyme 4 | 4,145
Ion Channel 3 | 344
Non-IDG 3 | 12,091

GO Process

protein hexamerization 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-3 PANX3 Tbio Ion Channel -1.66465 45.0 71
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
ATP-dependent zinc metalloprotease YME1L1 YME1L1 Tbio Enzyme -2.42377 268.0 75
Mitochondrial proton/calcium exchanger protein LETM1 Tbio Non-IDG -1.54149 41.5 189
Ornithine aminotransferase, mitochondrial OAT Tchem Enzyme -2.87569 729.0 148
S-adenosylmethionine synthase isoform type-2 MAT2A Tbio Enzyme -1.91969 84.1 242
Twinkle protein, mitochondrial TWNK Tbio Non-IDG -2.18726 156.1 146
Spastin SPAST Tbio Non-IDG -2.41619 260.3 129
Transitional endoplasmic reticulum ATPase VCP Tchem Enzyme -2.84978 736.4 416