Development Level

Tbio 21 | 11,178
Tchem 2 | 1,885

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased mean corpuscular vol... 2 | 79
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating lipase l... 1 | 3
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
pale yolk sac 1 | 25
pallor 1 | 34
trunk curl 1 | 16

Disease

Carcinoma 16 | 11,192
osteosarcoma 11 | 7,766
ovarian cancer 11 | 8,297
Cancer 7 | 2,388
atypical teratoid / rhabdoid tumor 6 | 4,971
ependymoma 6 | 4,559
glioblastoma 6 | 5,635
group 3 medulloblastoma 6 | 4,002
medulloblastoma, large-cell 6 | 6,086
psoriasis 6 | 6,514
Kidney cancer 5 | 2,548
astrocytic glioma 5 | 2,530
ulcerative colitis 5 | 1,765
Multiple myeloma 4 | 1,296
acute quadriplegic myopathy 4 | 1,133
astrocytoma 4 | 1,113
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,204
lung cancer 4 | 4,607
lung carcinoma 4 | 2,755
oligodendroglioma 4 | 2,768
primitive neuroectodermal tumor 4 | 2,957
Autosomal recessive predisposition 3 | 1,407
Bipolar Disorder 3 | 646
Breast cancer 3 | 3,469
Pick disease 3 | 1,856
Prostatic Neoplasms 3 | 472
Waldenstrons macroglobulinemia 3 | 742
juvenile dermatomyositis 3 | 1,147
medulloblastoma 3 | 702
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,911
subependymal giant cell astrocytoma 3 | 2,230
Animal Mammary Neoplasms 2 | 130
Asthma 2 | 370
Astrocytoma, Pilocytic 2 | 3,006
Colorectal Neoplasms 2 | 235
Duchenne muscular dystrophy 2 | 587
Epilepsy 2 | 775
HIV Infections 2 | 94
Hemiplegia and hemiparesis 2 | 33
Hypertensive disease 2 | 278
Infantile onset 2 | 236
Keloid 2 | 37
Kidney disease 2 | 411
Mammary Neoplasms, Animal 2 | 130
Mammary Neoplasms, Experimental 2 | 147
Muscle hypotonia 2 | 562
Myocardial Infarction 2 | 142
Myocardial Ischemia 2 | 162
Neoplasm Invasiveness 2 | 151
Neurodegenerative disease 2 | 402
Nonorganic psychosis 2 | 83
Psychotic Disorders 2 | 150
Schizophrenia 2 | 1,136
Thrombocythemia, Essential 2 | 12
acute lymphocytic leukemia 2 | 33
adult high grade glioma 2 | 3,701
breast carcinoma 2 | 1,589
dermatomyositis 2 | 941
diabetes mellitus 2 | 1,683
gastric carcinoma 2 | 781
inflammatory breast cancer 2 | 272
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
malignant mesothelioma 2 | 3,135
non-small cell lung cancer 2 | 2,799
pancreatic cancer 2 | 2,322
pituitary cancer 2 | 1,915
tuberculosis 2 | 1,963
Asthma, Occupational 1 | 10
Berylliosis 1 | 26
Bradyopsia 1 | 9
Cerebellar vermis aplasia or hypoplasia 1 | 11
Cerebellar vermis aplasia/ hypoplasia 1 | 11
Coats disease 1 | 13
Colonic benign neoplasm 1 | 3
Copper-Overload Cirrhosis 1 | 11
Decreased subcutaneous adipose tissue 1 | 12
Dejerine-Sottas Disease (disorder) 1 | 5
Dejerine-Sottas disease 1 | 5
Dry Eye Syndromes 1 | 8
Ewings sarcoma 1 | 8
Exudative retinopathy 1 | 4
Hammer Toe 1 | 23
Hereditary Motor and Sensory Neuropathies 1 | 5
Hereditary Sensory and Motor Neuropathy 1 | 5
Hypertrophic nerve changes 1 | 5
Legionnaires' disease 1 | 20
Macule 1 | 19
Muscle weakness of upper limb 1 | 5
Occupational Diseases 1 | 11
Onion bulb formation 1 | 18
Optic disc abnormalities 1 | 11
Polycystic Kidney, Autosomal Dominant 1 | 7
Rett syndrome 1 | 17
Sarcoma, Ewing 1 | 4
Sclerosis of skull base 1 | 5
Segmental demyelination/remyelination 1 | 7
Severe visual impairment 1 | 15
Slender build 1 | 14
Ulnar claw 1 | 6

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400

GO Process

protein export from nucleus 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exportin-5 XPO5 Tbio Non-IDG -1.97361 83.7 166
Double-stranded RNA-specific adenosine deaminase ADAR Tbio Enzyme -2.87338 784.2 197
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Exportin-7 XPO7 Tbio Non-IDG -1.01893 10.2 101
Eukaryotic translation initiation factor 5A-1 EIF5A Tbio Non-IDG -2.10288 142.0 231
Exportin-6 XPO6 Tbio Non-IDG -1.53980 34.5 29
Ankyrin repeat and LEM domain-containing protein 1 ANKLE1 Tbio Non-IDG -1.22574 16.7 31
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -1.04073 10.5 78
Nuclear transport factor 2 NUTF2 Tbio Non-IDG -2.62403 421.6 97