Development Level

Tclin 6 | 613
Tchem 4 | 1,598
Tbio 1 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
preweaning lethality, incomple... 1 | 499

Disease

Cancer 9 | 2,499
Carcinoma 8 | 11,493
osteosarcoma 8 | 7,950
Multiple myeloma 6 | 1,332
Peripheral T-cell lymphoma 6 | 25
Primary cutaneous T-cell lymphoma 6 | 29
Obesity 5 | 678
Schizophrenia 5 | 1,160
Mood Disorders 4 | 184
diabetes mellitus 4 | 1,728
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
subependymal giant cell astrocytoma 4 | 2,287
Familial primary pulmonary hypertension 3 | 11
Heart Diseases 3 | 43
Mental Depression 3 | 333
Short hands 3 | 50
Short stature 3 | 531
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Abnormality of cardiovascular system morphology 2 | 23
Abnormally small eyeball 2 | 97
Anteverted nostril 2 | 191
Astrocytoma, Pilocytic 2 | 3,081
Bilateral single transverse palmar creases 2 | 34
Bowed and upward slanting eyebrows 2 | 41
Brachydactyly 2 | 156
Carcinoma, Squamous Cell 2 | 110
Cocaine-Related Disorders 2 | 92
Cognitive delay 2 | 608
Decreased size of eyeball 2 | 97
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Enophthalmos 2 | 75
Fatty liver disease 2 | 103
Fetal Growth Retardation 2 | 189
Frontal bossing 2 | 157
Global developmental delay 2 | 608
Heart disease 2 | 306
Huntington's disease 2 | 76
Hydrocephalus 2 | 152
Hypoplastic feet 2 | 66
Infant, Small for Gestational Age 2 | 176
Intellectual disability 2 | 1,016
Intrauterine retardation 2 | 176
Joint hyperflexibility 2 | 78
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microphthalmos 2 | 100
Muscle hypotonia 2 | 571
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Short nose 2 | 132
Small head 2 | 374
Small nose 2 | 132
Sparse eyebrow 2 | 42
Squamous cell carcinoma 2 | 129
Sunken eyes 2 | 63
Syndactyly of the toes 2 | 45
Thick, flared eyebrows 2 | 41
Thin hypoplastic alae nasi 2 | 51
Thin lips 2 | 49
Upward slant of palpebral fissure 2 | 75
Vascular disease 2 | 319
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
primitive neuroectodermal tumor 2 | 3,035
Accessory nipple 1 | 11
Autism Spectrum Disorders 1 | 75
Chromosome 2q37 deletion syndrome 1 | 4
Congenital diaphragmatic hernia 1 | 67
Convex nasal bridge 1 | 57
Decreased projection of midface 1 | 105
Gestational diabetes 1 | 26
Hyperglycemia 1 | 137
Hypertrophy 1 | 17
Hypotrophic midface 1 | 105
Midface retrusion 1 | 105
Narrow face 1 | 54
Open mouth 1 | 45
Pneumonia, Pneumococcal 1 | 6
Prominent nasal bridge 1 | 57
Pseudohypoparathyroidism 1 | 18
Round face 1 | 45
Round, full face 1 | 45
Small midface 1 | 105
Streptococcal pneumonia 1 | 6
Syndactyly of fingers 1 | 48
Systemic scleroderma 1 | 60

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Epigenetic 10 | 242
Non-IDG 1 | 12,091

GO Process

protein deacetylation 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NAD-dependent protein deacylase sirtuin-5, mitochondrial SIRT5 Tchem Epigenetic -2.36015 219.3 427
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.93639 70.1 171
NAD-dependent protein deacetylase sirtuin-2 SIRT2 Tchem Epigenetic -2.83863 706.1 386
Histone deacetylase 3 HDAC3 Tclin Epigenetic -2.28457 142.9 673
Histone deacetylase 10 HDAC10 Tclin Epigenetic -1.63837 44.1 314
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.19942 147.5 520
NAD-dependent protein deacetylase sirtuin-3, mitochondrial SIRT3 Tchem Epigenetic -2.74514 583.3 550
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.50639 3413.7 733
Histone deacetylase 4 HDAC4 Tclin Epigenetic -2.42231 255.5 825