Development Level

Tbio 99 | 11,651
Tchem 16 | 1,388
Tclin 5 | 612
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 12 | 979
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to o... 4 | 239
increased lean body mass 4 | 172
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
decreased vertical activity 2 | 208
increased bone mineral content 2 | 108
increased fasted circulating g... 2 | 76
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal motor learning 1 | 3
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
female infertility 1 | 60
hemorrhage 1 | 23
hydroencephaly 1 | 14
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Carcinoma 85 | 11,493
ovarian cancer 80 | 8,520
osteosarcoma 64 | 7,950
glioblastoma 62 | 5,792
medulloblastoma, large-cell 61 | 6,241
lung cancer 55 | 4,740
atypical teratoid / rhabdoid tumor 50 | 5,112
psoriasis 49 | 6,694
group 3 medulloblastoma 47 | 4,104
adult high grade glioma 40 | 3,801
ependymoma 40 | 4,679
Cancer 39 | 2,499
malignant mesothelioma 39 | 3,232
primitive neuroectodermal tumor 34 | 3,035
Astrocytoma, Pilocytic 33 | 3,081
Breast cancer 33 | 3,578
non-small cell lung cancer 31 | 2,890
invasive ductal carcinoma 29 | 2,951
subependymal giant cell astrocytoma 29 | 2,287
lung carcinoma 27 | 2,843
oligodendroglioma 27 | 2,850
pancreatic cancer 27 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
astrocytic glioma 25 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
lung adenocarcinoma 25 | 2,716
interstitial cystitis 23 | 2,312
ductal carcinoma in situ 22 | 1,745
Kidney cancer 21 | 2,613
Schizophrenia 21 | 1,160
breast carcinoma 20 | 1,638
Autosomal recessive predisposition 19 | 1,442
colon cancer 19 | 1,478
Pick disease 18 | 1,894
Rheumatoid arthritis 18 | 1,191
astrocytoma 18 | 1,146
ulcerative colitis 18 | 1,819
cystic fibrosis 17 | 1,696
adrenocortical carcinoma 16 | 1,428
acute quadriplegic myopathy 15 | 1,158
pituitary cancer 15 | 1,972
cutaneous lupus erythematosus 14 | 1,057
diabetes mellitus 14 | 1,728
pediatric high grade glioma 14 | 1,064
tuberculosis 14 | 2,010
juvenile dermatomyositis 13 | 1,187
Breast Neoplasms 12 | 445
Intellectual disability 12 | 1,016
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
primary Sjogren syndrome 12 | 735
Bipolar Disorder 11 | 666
Multiple myeloma 11 | 1,332
Short stature 11 | 531
group 4 medulloblastoma 11 | 1,855
primary pancreatic ductal adenocarcinoma 11 | 1,109
Liver Cirrhosis, Experimental 10 | 769
Mammary Neoplasms 10 | 425
acute myeloid leukemia 10 | 783
spina bifida 10 | 1,074
Alzheimer's disease 9 | 658
Amyotrophic lateral sclerosis 9 | 451
Epilepsy 9 | 792
Melanoma 9 | 711
Muscle hypotonia 9 | 571
Prostatic Neoplasms 9 | 495
Strabismus 9 | 270
esophageal adenocarcinoma 9 | 737
gastric carcinoma 9 | 807
Atopic dermatitis 8 | 952
Cognitive delay 8 | 608
Dull intelligence 8 | 645
Global developmental delay 8 | 608
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Poor school performance 8 | 645
Seizures 8 | 596
Splenomegaly 8 | 190
dermatomyositis 8 | 966
medulloblastoma 8 | 720
nasopharyngeal carcinoma 8 | 1,058
Down syndrome 7 | 499
Endometriosis 7 | 540
Liver cancer 7 | 604
Nystagmus 7 | 317
Osteoporosis 7 | 363
Polycystic ovary syndrome 7 | 360
Renal Cell Carcinoma 7 | 214
Skin cancer 7 | 469
Small head 7 | 374
Waldenstrons macroglobulinemia 7 | 765
pancreatic carcinoma 7 | 562
Acquired scoliosis 6 | 281
Crohn's disease 6 | 321
Curvature of spine 6 | 282
Failure to gain weight 6 | 365
Hepatomegaly 6 | 285
Pediatric failure to thrive 6 | 365

Tissue

Endocrine System 124 | 18,159
Male tissues 124 | 17,142
Female tissues 123 | 17,400
Skin and soft tissues 123 | 17,230
Urinary Tract 123 | 16,678
Digestive Tract 122 | 17,369
Liver and Pancreas 122 | 16,750
Nervous System 122 | 16,725
Blood and immune system 120 | 16,909
Respiratory system 119 | 16,393
Cardiovascular System 115 | 15,192

Target Family

Non-IDG 88 | 12,091
Enzyme 14 | 4,145
Transcription Factor 12 | 1,400
Transporter 6 | 473
Kinase 3 | 634
Epigenetic 2 | 242

GO Process

protein complex assembly 125 | 125
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Chromatin assembly factor 1 subunit A CHAF1A Tbio Non-IDG -1.60312 40.7 157
Chromatin assembly factor 1 subunit B CHAF1B Tbio Non-IDG -1.02167 9.99 181
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.35413 26.1 138
Transcription factor AP-4 TFAP4 Tbio Transcription Factor -1.33384 19.4 276
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.71108 45.2 164
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.66116 45.2 127
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Gamma-tubulin complex component 2 TUBGCP2 Tdark Non-IDG -0.75255 4.80 109
Centromere/kinetochore protein zw10 homolog ZW10 Tbio Non-IDG -1.64269 41.5 124