Development Level

Tbio 86 | 10,625
Tchem 18 | 1,890
Tclin 6 | 602
Tdark 5 | 7,003

IMPC Term

preweaning lethality, complete... 7 | 633
embryonic lethality prior to t... 4 | 187
embryonic lethality prior to o... 3 | 148
decreased circulating choleste... 2 | 85
decreased lean body mass 2 | 195
decreased monocyte cell number 2 | 28
decreased neutrophil cell numb... 2 | 37
decreased total body fat amoun... 2 | 186
increased lean body mass 2 | 107
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal spinal cord morpholog... 1 | 8
cataract 1 | 26
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased grip strength 1 | 123
decreased late germinal center... 1 | 2
decreased myeloid cell number ... 1 | 1
decreased pre-pro B cell numbe... 1 | 2
decreased pro-B cell number 1 | 2
decreased spleen weight 1 | 13
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased T cell number 1 | 15
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased circulating phosphat... 1 | 24
increased early germinal cente... 1 | 2
increased fasted circulating g... 1 | 68
increased immature B cell numb... 1 | 1
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased pre-B cell number 1 | 1
male infertility 1 | 62
narrow eye opening 1 | 15
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
thrombocytopenia 1 | 46
tremors 1 | 34
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 72 | 8,484
osteosarcoma 60 | 7,933
medulloblastoma, large-cell 54 | 6,234
glioblastoma 52 | 5,572
lung cancer 52 | 4,466
psoriasis 47 | 6,685
malignant mesothelioma 40 | 3,162
atypical teratoid / rhabdoid tumor 35 | 4,369
Cancer 33 | 2,346
pediatric high grade glioma 31 | 2,712
primitive neuroectodermal tumor 30 | 3,031
non-small cell lung cancer 29 | 2,798
pilocytic astrocytoma 29 | 3,086
Breast cancer 27 | 3,094
invasive ductal carcinoma 27 | 2,950
subependymal giant cell astrocytoma 27 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
lung carcinoma 25 | 2,844
oligodendroglioma 25 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
interstitial cystitis 23 | 2,299
lung adenocarcinoma 23 | 2,713
pancreatic cancer 23 | 2,300
astrocytoma 22 | 1,493
group 3 medulloblastoma 21 | 2,254
Carcinoma 20 | 2,147
ductal carcinoma in situ 20 | 1,745
colon cancer 19 | 1,475
medulloblastoma 18 | 1,524
ulcerative colitis 18 | 2,087
Rheumatoid Arthritis 17 | 1,160
astrocytic glioma 17 | 2,241
cystic fibrosis 17 | 1,665
ependymoma 17 | 2,514
posterior fossa group A ependymoma 16 | 1,511
Pick disease 15 | 1,893
acute quadriplegic myopathy 15 | 1,157
adrenocortical carcinoma 15 | 1,427
adult high grade glioma 15 | 2,148
breast carcinoma 15 | 1,614
group 4 medulloblastoma 15 | 1,875
pituitary cancer 15 | 1,972
cutaneous lupus erythematosus 14 | 1,056
diabetes mellitus 13 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
atypical teratoid/rhabdoid tumor 12 | 1,095
juvenile dermatomyositis 12 | 1,189
Multiple myeloma 11 | 1,327
primary Sjogren syndrome 11 | 789
tuberculosis 11 | 1,557
Alzheimer's disease 10 | 644
Mammary Neoplasms 10 | 410
acute myeloid leukemia 9 | 780
gastric carcinoma 9 | 832
posterior fossa group B ependymoma 9 | 1,530
primary pancreatic ductal adenocarcinoma 9 | 1,271
Amyotrophic Lateral Sclerosis 8 | 431
Down syndrome 8 | 548
dermatomyositis 8 | 933
esophageal adenocarcinoma 8 | 737
pancreatic carcinoma 8 | 567
spina bifida 8 | 1,064
Atopic dermatitis 7 | 944
Intellectual disability 7 | 573
Prostatic Neoplasms 7 | 471
Waldenstrons macroglobulinemia 7 | 765
nasopharyngeal carcinoma 7 | 1,056
Crohn's disease 6 | 304
Gaucher disease type 1 6 | 171
IGA Glomerulonephritis 6 | 454
Lung Neoplasms 6 | 171
Neoplastic Cell Transformation 6 | 81
Obesity 6 | 616
Renal Cell Carcinoma 6 | 199
non-small cell lung carcinoma 6 | 413
tuberculosis and treatment for 6 months 6 | 686
Bladder Neoplasm 5 | 109
Kidney disease 5 | 396
Melanoma 5 | 261
Multiple Sclerosis 5 | 498
Neoplastic Syndromes, Hereditary 5 | 48
Stomach Neoplasms 5 | 282
active Crohn's disease 5 | 918
active ulcerative colitis 5 | 477
fibroadenoma 5 | 557
nephrosclerosis 5 | 329
sonic hedgehog group medulloblastoma 5 | 1,482
Allergic hypersensitivity disease 4 | 123
Cerebrovascular disease 4 | 231
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Duchenne muscular dystrophy 4 | 602
Endometriosis 4 | 535
Heart disease 4 | 279
Hypersensitivity reaction type II disease 4 | 235
Hypertensive disease 4 | 193
Polycystic Ovary Syndrome 4 | 332
Schizophrenia 4 | 501
Vascular disease 4 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499

Tissue

Cardiovascular System 115 | 17,958
Digestive Tract 115 | 18,473
Endocrine System 115 | 18,512
Female tissues 115 | 18,647
Male tissues 115 | 17,969
Nervous System 115 | 18,561
Skin and soft tissues 115 | 18,115
Urinary Tract 115 | 18,444
Blood and immune system 114 | 17,995
Liver and Pancreas 114 | 18,136
Respiratory system 114 | 17,484

Target Family

Non-IDG 79 | 11,971
Enzyme 14 | 4,146
Transcription Factor 10 | 1,400
Transporter 6 | 473
Kinase 3 | 634
Epigenetic 2 | 242
Ion Channel 1 | 341

GO Process

protein complex assembly 115 | 115
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
Wiskott-Aldrich syndrome protein family member 3 WASF3 Tbio Non-IDG -2.43045 280.1 123
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Interleukin-2 receptor subunit beta IL2RB Tclin Non-IDG -2.08442 120.9 537
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.02060 88.8 104