Development Level

Tchem 7 | 1,598
Tbio 4 | 11,445
Tclin 2 | 613

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased circulating alkaline... 1 | 122
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
lung cancer 9 | 4,740
ovarian cancer 9 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
diabetes mellitus 6 | 1,728
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Neurodegenerative disease 5 | 414
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Cancer 4 | 2,499
active ulcerative colitis 4 | 764
adult high grade glioma 4 | 3,801
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
subependymal giant cell astrocytoma 4 | 2,287
Atherosclerosis 3 | 291
Autosomal recessive predisposition 3 | 1,442
Dermatitis 3 | 157
Liver Cirrhosis, Experimental 3 | 769
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
Anemia 2 | 365
Ataxia, Appendicular 2 | 25
Babinski Reflex 2 | 100
Cardiomyopathies 2 | 110
Cerebellar Ataxia 2 | 304
Cerebellar Dysmetria 2 | 56
Cerebrovascular disease 2 | 238
Dysarthria 2 | 192
Gait Ataxia 2 | 51
Inflammation 2 | 120
Kidney Diseases 2 | 114
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Multiple myeloma 2 | 1,332
Muscle Weakness 2 | 170
Obesity 2 | 678
Parkinsonian Disorders 2 | 56
Pneumonia 2 | 174
Prostatic Neoplasms 2 | 495
Spastic Ataxia 2 | 18
Vascular disease 2 | 319
active Crohn's disease 2 | 922
group 3 medulloblastoma 2 | 4,104
interstitial lung disease 2 | 298
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
Abdominal pain, episodic 1 | 9
Adenocarcinoma 1 | 122
Angioedema 1 | 38
Ataxia, Spinocerebellar 1 | 16
Brain Injuries 1 | 65
C1 inhibitor deficiency 1 | 8
Cholera 1 | 34
Cowpox 1 | 16
Dysdiadochokinesis 1 | 25
Dysmetric saccades 1 | 9
Early myoclonic encephalopathy 1 | 15
Epithelial tumor of ovary 1 | 3
Factor XII deficiency 1 | 13
Gait imbalance 1 | 17
Hepatitis 1 | 67
Human immunodeficiency virus infectious disease 1 | 138
Increased intramyocellular lipid droplets 1 | 13
Kyphosis deformity of spine 1 | 114
Liver Neoplasms, Experimental 1 | 59
Lower limb hyperreflexia 1 | 10
Muckle-Wells syndrome 1 | 12
Myocardial Reperfusion Injury 1 | 37
Nasopharyngitis 1 | 11
Nephroblastoma 1 | 51
Nystagmus, End-Position 1 | 12
Ophthalmoparesis 1 | 11
Paraparesis, Spastic 1 | 16
Periodontal disease 1 | 40
Pertussis 1 | 20
Pulmonary Fibrosis 1 | 106
SPASTIC ATAXIA 5, AUTOSOMAL RECESSIVE 1 | 1
SPINOCEREBELLAR ATAXIA 28 1 | 1
Scoliosis 1 | 44
Sensory neuropathy 1 | 20
Slowed saccades 1 | 12
Thromboembolism 1 | 15
Tonic - clonic seizures 1 | 44
Tularemia 1 | 23
chronic kidney disease 1 | 90
intermittent abdominal pain 1 | 9
spinocerebellar ataxia type 28 1 | 3

Tissue

Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Respiratory system 11 | 16,393
Cardiovascular System 8 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 3 | 12,091

GO Process

protein autoprocessing 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroendocrine convertase 2 PCSK2 Tchem Enzyme -2.00248 109.8 132
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Frataxin, mitochondrial FXN Tbio Non-IDG -3.02739 1114.8 403
Transmembrane protease serine 2 TMPRSS2 Tchem Enzyme -2.66686 438.2 221
Cathepsin E CTSE Tchem Enzyme -2.33724 227.7 192
Hemojuvelin HFE2 Tbio Non-IDG -2.16845 146.9 284
Proprotein convertase subtilisin/kexin type 9 PCSK9 Tclin Enzyme -3.23656 1735.1 468
Calpain-2 catalytic subunit CAPN2 Tchem Non-IDG -1.69585 48.5 220
Coagulation factor XII F12 Tchem Enzyme -2.86349 729.4 400