Development Level

Tbio 22 | 10,625
Tchem 9 | 1,890
Tdark 5 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
embryonic lethality prior to o... 2 | 148
abnormal behavior 1 | 226
abnormal esophagus morphology 1 | 4
abnormal iris morphology 1 | 12
abnormal pancreas morphology 1 | 6
abnormal skin coloration 1 | 18
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent adrenal gland 1 | 1
absent lymph nodes 1 | 3
anophthalmia 1 | 20
decreased circulating calcium ... 1 | 33
decreased circulating glycerol... 1 | 19
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
enlarged thymus 1 | 4
increased circulating free fat... 1 | 17
increased circulating glycerol... 1 | 11
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased mean corpuscular vol... 1 | 91
prenatal lethality prior to he... 1 | 64
shortened QT interval 1 | 4
small adrenal glands 1 | 15
small spleen 1 | 11

Disease

ovarian cancer 23 | 8,484
osteosarcoma 18 | 7,933
medulloblastoma, large-cell 16 | 6,234
psoriasis 15 | 6,685
glioblastoma 13 | 5,572
Congenital disorder of glycosylation 12 | 53
lung cancer 12 | 4,466
atypical teratoid / rhabdoid tumor 10 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
pilocytic astrocytoma 10 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
group 3 medulloblastoma 8 | 2,254
Breast cancer 7 | 3,094
astrocytoma 7 | 1,493
pancreatic cancer 7 | 2,300
Multiple myeloma 6 | 1,327
adult high grade glioma 6 | 2,148
lung adenocarcinoma 6 | 2,713
malignant mesothelioma 6 | 3,162
ulcerative colitis 6 | 2,087
group 4 medulloblastoma 5 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Cancer 4 | 2,346
active Crohn's disease 4 | 918
diabetes mellitus 4 | 1,663
ependymoma 4 | 2,514
esophageal adenocarcinoma 4 | 737
juvenile dermatomyositis 4 | 1,189
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
pediatric high grade glioma 4 | 2,712
primitive neuroectodermal tumor 4 | 3,031
tuberculosis 4 | 1,557
Pick disease 3 | 1,893
cystic fibrosis 3 | 1,665
interstitial cystitis 3 | 2,299
lung carcinoma 3 | 2,844
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group A ependymoma 3 | 1,511
spina bifida 3 | 1,064
Amyotrophic Lateral Sclerosis 2 | 431
Botulism 2 | 20
Desbuquois dysplasia 2 | 9
IGA Glomerulonephritis 2 | 454
Leukocyte adhesion deficiency 2 | 15
Meniere's disease 2 | 24
Polycystic Ovary Syndrome 2 | 332
Prostatic Neoplasms 2 | 471
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
colon cancer 2 | 1,475
dermatomyositis 2 | 933
invasive ductal carcinoma 2 | 2,950
nephrosclerosis 2 | 329
pancreatic carcinoma 2 | 567
primary Sjogren syndrome 2 | 789
protein-losing enteropathy 2 | 11
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686
Brugada syndrome 1 | 26
Cannabis abuse 1 | 6
Congenital Disorder Of Glycosylation, Type IIB 1 | 1
Congenital Disorder Of Glycosylation, Type IIID 1 | 1
Congenital disorder of glycosylation type 1C 1 | 1
Congenital disorder of glycosylation type 2D 1 | 1
Congenital muscular dystrophy 1 | 25
Congenital myasthenic syndrome 1 | 28
Craniofacial Abnormalities 1 | 147
Cutis laxa 1 | 28
Disease Progression 1 | 125
Drug allergy 1 | 36
Erythromelalgia 1 | 8
Exanthem 1 | 39
Gout 1 | 93
Heart conduction disease 1 | 65
Hepatic vein thrombosis 1 | 8
Leber congenital amaurosis 1 | 72
Muscle Weakness 1 | 92
Myelofibrosis 1 | 11
Myopathy 1 | 128
Neuropathy 1 | 210
Polycythemia Vera 1 | 24
Portal vein thrombosis 1 | 9
Ptosis 1 | 42
Sclerocornea 1 | 16
Sporotrichosis 1 | 5
Stomach Neoplasms 1 | 282
Thrombocytosis 1 | 8
Walker-Warburg syndrome 1 | 10
active ulcerative colitis 1 | 477
glioblastoma multiforme 1 | 347
non-small cell lung carcinoma 1 | 413

Tissue

Digestive Tract 36 | 18,473
Male tissues 36 | 17,969
Nervous System 36 | 18,561
Blood and immune system 35 | 17,995
Endocrine System 35 | 18,512
Female tissues 35 | 18,647
Liver and Pancreas 35 | 18,136
Respiratory system 35 | 17,484
Skin and soft tissues 35 | 18,115
Urinary Tract 35 | 18,444
Cardiovascular System 34 | 17,958

Target Family

Enzyme 30 | 4,146
Non-IDG 5 | 11,971
Ion Channel 1 | 341

GO Process

protein N-linked glycosylation 36 | 36
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

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