Development Level

Tbio 21 | 11,651
Tchem 1 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

thrombocytosis 3 | 27
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
increased mean corpuscular hem... 2 | 96
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal gait 1 | 69
corneal opacity 1 | 32
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased circulating HDL chol... 1 | 68
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating thyroxin... 1 | 7
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
long tibia 1 | 25
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
ovarian cancer 16 | 8,520
osteosarcoma 13 | 7,950
medulloblastoma, large-cell 12 | 6,241
psoriasis 9 | 6,694
glioblastoma 7 | 5,792
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
lung cancer 6 | 4,740
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
spina bifida 5 | 1,074
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
Atopic dermatitis 3 | 952
Multiple myeloma 3 | 1,332
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Carcinoma, Non-Small-Cell Lung 2 | 107
Crohn's disease 2 | 321
Pick disease 2 | 1,894
acute quadriplegic myopathy 2 | 1,158
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
non-small cell lung carcinoma 2 | 317
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
Acne 1 | 52
Anxiety 1 | 136
Anxiety disease 1 | 113
Arsenic Poisoning 1 | 62
Ataxia, Truncal 1 | 21
Autosomal dominant cerebellar ataxia 1 | 33
Blind loop syndrome 1 | 2
Cell Transformation, Neoplastic 1 | 97
Congestive heart failure 1 | 113
Deglutition Disorders 1 | 132
Dermatologic disorders 1 | 93
Distal amyotrophy 1 | 51
Ecchymosis 1 | 66
Fatigue 1 | 182
Frequent fractures 1 | 53
Friedreich ataxia 1 | 24
Generalized hirsutism 1 | 36
Hypokalemia 1 | 52
Immunologic Deficiency Syndromes 1 | 113
Increased fracture rate 1 | 53
Increased tendency to bruise 1 | 66
Juvenile rheumatoid arthritis 1 | 111
Lupus Erythematosus, Systemic 1 | 67
Lupus nephritis 1 | 13
Lymphoid leukemia 1 | 160
Lymphoma, Follicular 1 | 18
Lymphoma, T-Cell, Cutaneous 1 | 22
Milium Cyst 1 | 16
Multiple system atrophy 1 | 29
Muscle Rigidity 1 | 49
Narcolepsy 1 | 72
Neoplastic Cell Transformation 1 | 89
Nerve Degeneration 1 | 121
Ovarian Neoplasms 1 | 102
PARKINSON DISEASE, LATE-ONSET 1 | 20
Panic disorder 1 | 61
Paralytic ileus 1 | 5
Postural instability 1 | 19
Restless legs syndrome 1 | 27
Round face 1 | 45
Round, full face 1 | 45
Skin Diseases 1 | 71
Sphincter disturbances 1 | 16
Spinocerebellar ataxia type 1 1 | 16
Spinocerebellar ataxia type 2 1 | 23
Telangiectasia of the skin 1 | 39
Thrombophlebitis 1 | 19
non-syndromic X-linked intellectual disability 1 | 20
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Enzyme 14 | 4,145
Non-IDG 9 | 12,091

GO Process

protein K63-linked deubiquitin... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BRISC and BRCA1-A complex member 1 BABAM1 Tbio Non-IDG -1.20557 16.7 162
BRISC and BRCA1-A complex member 2 BABAM2 Tbio Non-IDG -1.84649 70.2 156
Ubiquitin carboxyl-terminal hydrolase 17 USP17L2 Tbio Enzyme -0.71476 13.1 100
Ubiquitin carboxyl-terminal hydrolase 20 USP20 Tbio Enzyme -1.05149 12.7 257
Ubiquitin carboxyl-terminal hydrolase 25 USP25 Tbio Enzyme -1.27999 19.7 162
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tbio Enzyme -1.72968 58.3 209
BRISC complex subunit Abraxas 2 ABRAXAS2 Tbio Non-IDG -0.34648 3.47 70
Lys-63-specific deubiquitinase BRCC36 BRCC3 Tbio Enzyme -1.15215 13.4 225
Tumor necrosis factor alpha-induced protein 3 TNFAIP3 Tbio Non-IDG -2.45615 259.2 309
Serine hydroxymethyltransferase, mitochondrial SHMT2 Tbio Enzyme -2.39227 240.3 137