Development Level

Tbio 17 | 10,625
Tchem 2 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

decreased lean body mass 3 | 195
preweaning lethality, complete... 3 | 633
decreased body weight 2 | 174
decreased gamma-delta T cell n... 2 | 18
increased NK cell number 2 | 19
increased alpha-beta T cell nu... 2 | 9
abnormal heart position or ori... 1 | 1
abnormal vocalization 1 | 21
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating choleste... 1 | 85
decreased effector memory CD4-... 1 | 6
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased mature B cell number 1 | 25
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased T cell number 1 | 15
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased effector memory CD4-... 1 | 15
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
thrombocytosis 1 | 23

Disease

osteosarcoma 12 | 7,933
medulloblastoma, large-cell 11 | 6,234
ovarian cancer 11 | 8,491
psoriasis 6 | 6,685
Carcinoma 5 | 2,147
atypical teratoid / rhabdoid tumor 5 | 4,369
lung cancer 5 | 4,473
diabetes mellitus 4 | 1,663
glioblastoma 4 | 5,572
lung carcinoma 4 | 2,844
malignant mesothelioma 4 | 3,163
medulloblastoma 4 | 1,524
spina bifida 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Breast cancer 3 | 3,098
Pick disease 3 | 1,893
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
ependymoma 3 | 2,514
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
primitive neuroectodermal tumor 3 | 3,031
tuberculosis and treatment for 6 months 3 | 686
Atopic dermatitis 2 | 944
Cancer 2 | 2,346
Rheumatoid Arthritis 2 | 1,170
active ulcerative colitis 2 | 477
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
lung adenocarcinoma 2 | 2,714
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pilocytic astrocytoma 2 | 3,086
Adenoma 1 | 165
Autosomal dominant cerebellar ataxia 1 | 34
Bipolar Disorder 1 | 266
Blind loop syndrome 1 | 2
Celiac disease 1 | 112
Cerebellar Ataxia 1 | 72
Cholangiocarcinoma 1 | 32
Choreatic disease 1 | 27
Chromosome 15q13.3 microdeletion syndrome 1 | 11
Congenital stationary night blindness 1 | 28
Congestive heart failure 1 | 36
Connective tissue disease 1 | 59
Cushing's syndrome 1 | 47
Dystonia 1 | 77
Friedreich ataxia 1 | 23
Gaucher disease type 1 1 | 171
Heart failure 1 | 80
Huntington's disease 1 | 72
Inflammatory dermatosis 1 | 38
Juvenile rheumatoid arthritis 1 | 105
Kennedy's disease 1 | 13
Lupus Erythematosus, Systemic 1 | 73
Lymphoma, Follicular 1 | 20
Lymphoma, T-Cell, Cutaneous 1 | 21
Machado-Joseph disease 1 | 18
Mesothelioma 1 | 40
Multiple Sclerosis 1 | 498
Multiple system atrophy 1 | 27
Narcolepsy 1 | 69
Neoplastic Cell Transformation 1 | 81
Nerve Degeneration 1 | 73
Neurodegenerative disease 1 | 383
Neuropathy 1 | 210
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paralytic ileus 1 | 2
Paraplegia 1 | 71
Parkinson's disease 1 | 364
Pneumonia 1 | 133
Polycystic Ovary Syndrome 1 | 334
Renal Cell Carcinoma 1 | 199
Restless legs syndrome 1 | 28
Sjogren's syndrome 1 | 23
Spinocerebellar ataxia type 1 1 | 16
Spinocerebellar ataxia type 2 1 | 19
Thrombophlebitis 1 | 16
Uveal melanoma 1 | 18
Waldenstrons macroglobulinemia 1 | 764
acute myeloid leukemia 1 | 785
acute quadriplegic myopathy 1 | 1,157
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,670
dentatorubral-pallidoluysian atrophy 1 | 21
familial melanoma 1 | 10
nasopharyngeal carcinoma 1 | 1,056
non-syndromic X-linked intellectual disability 1 | 21
pancreatic cancer 1 | 2,300
pediatric high grade glioma 1 | 2,712
pituitary cancer 1 | 1,972
sonic hedgehog group medulloblastoma 1 | 1,482
systemic lupus erythematosus 1 | 172
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327

Tissue

Cardiovascular System 20 | 17,957
Female tissues 20 | 18,646
Male tissues 20 | 17,968
Nervous System 20 | 18,560
Blood and immune system 19 | 17,994
Digestive Tract 19 | 18,472
Liver and Pancreas 19 | 18,135
Urinary Tract 19 | 18,443
Endocrine System 18 | 18,511
Skin and soft tissues 18 | 18,114
Respiratory system 17 | 17,483

Target Family

Enzyme 13 | 4,146
Non-IDG 7 | 11,969

GO Process

protein K48-linked deubiquitin... 20 | 20
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 17 USP17L2 Tbio Enzyme -0.62169 10.9 79
OTU domain-containing protein 4 OTUD4 Tbio Non-IDG -0.43270 3.02 114
Ataxin-3 ATXN3 Tbio Non-IDG -2.85838 721.6 233
Deubiquitinating protein VCIP135 VCPIP1 Tbio Non-IDG -0.78073 6.33 75
Ubiquitin thioesterase OTU1 YOD1 Tbio Enzyme -1.62463 37.1 98
Ubiquitin carboxyl-terminal hydrolase BAP1 BAP1 Tbio Enzyme -2.03345 107.2 280
Ubiquitin thioesterase OTUB2 OTUB2 Tbio Enzyme -0.93576 9.55 221
Tumor necrosis factor alpha-induced protein 3 TNFAIP3 Tbio Non-IDG -2.40500 236.6 294
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tchem Enzyme -1.67600 52.9 189
Ubiquitin carboxyl-terminal hydrolase 5 USP5 Tbio Enzyme -2.20066 153.1 200