Development Level

Tbio 5 | 10,625

IMPC Term

abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating total pr... 1 | 20
increased heart weight 1 | 37
increased mean corpuscular vol... 1 | 91
tremors 1 | 34

Disease

psoriasis 5 | 6,685
ovarian cancer 3 | 8,492
Alzheimer's disease 2 | 644
Parkinson's disease 2 | 364
astrocytic glioma 2 | 2,241
ependymoma 2 | 2,514
glioblastoma 2 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
medulloblastoma, large-cell 2 | 6,234
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
osteosarcoma 2 | 7,933
primitive neuroectodermal tumor 2 | 3,031
Anemia 1 | 252
Angelman syndrome 1 | 38
Atopic dermatitis 1 | 944
Autistic Disorder 1 | 320
Autoimmune disease, multisystem, with facial dysmorphism 1 | 1
Autoimmune disease, syndromic multisystem 1 | 1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 7
Breast cancer 1 | 3,099
Cancer 1 | 2,346
Colonic Neoplasms 1 | 126
Dementia 1 | 129
Dystonia 1 | 77
Endometriosis 1 | 535
Fanconi Anemia 1 | 22
Fanconi anemia complementation group T 1 | 1
Fanconi anemia, complementation group t 1 | 1
Fanconi's anemia 1 | 50
IGA Glomerulonephritis 1 | 454
Intellectual disability 1 | 573
Intervertebral Disc Degeneration 1 | 5
Learning Disorders 1 | 27
Leprosy 1 | 77
Liddle syndrome 1 | 14
Lung Neoplasms 1 | 171
Manganese Poisoning 1 | 11
Memory Disorders 1 | 36
Multiple system atrophy 1 | 27
Nerve Degeneration 1 | 73
Neurodegenerative disease 1 | 383
Ovarian Cysts 1 | 34
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paraplegia 1 | 71
Parkinson Disease 1 | 105
Parkinson Disease 2, Autosomal Recessive Juvenile 1 | 3
Parkinson disease 2 1 | 1
Parkinsonian Disorders 1 | 23
Pick disease 1 | 1,893
Rheumatoid Arthritis 1 | 1,171
Secondary Parkinson Disease 1 | 9
TREMOR, HEREDITARY ESSENTIAL, 1 1 | 2
Toxic encephalopathy 1 | 131
adrenocortical carcinoma 1 | 1,427
atypical teratoid / rhabdoid tumor 1 | 4,369
breast carcinoma 1 | 1,614
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
invasive ductal carcinoma 1 | 2,950
lung adenocarcinoma 1 | 2,714
lung cancer 1 | 4,473
lung carcinoma 1 | 2,844
medulloblastoma 1 | 1,524
nasopharyngeal carcinoma 1 | 1,056
ovarian neoplasm 1 | 97
pancreatic cancer 1 | 2,300
pilocytic astrocytoma 1 | 3,086
pituitary cancer 1 | 1,972
progressive supranuclear palsy 1 | 674
sarcoidosis 1 | 368
spina bifida 1 | 1,064

Tissue

Blood and immune system 5 | 17,995
Cardiovascular System 5 | 17,958
Digestive Tract 5 | 18,473
Endocrine System 5 | 18,512
Female tissues 5 | 18,647
Liver and Pancreas 5 | 18,136
Male tissues 5 | 17,969
Nervous System 5 | 18,561
Respiratory system 5 | 17,484
Skin and soft tissues 5 | 18,115
Urinary Tract 5 | 18,444

Target Family

Non-IDG 3 | 11,969
Enzyme 2 | 4,146

GO Process

protein K29-linked ubiquitinat... 5 | 5
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-conjugating enzyme E2 D4 UBE2D4 Tbio Non-IDG -0.02803 0.45 111
E3 ubiquitin-protein ligase Itchy homolog ITCH Tbio Enzyme -2.02628 97.0 206
Ubiquitin-conjugating enzyme E2 T UBE2T Tbio Non-IDG -1.17893 14.7 175
Ubiquitin-conjugating enzyme E2 S UBE2S Tbio Non-IDG -2.34707 156.2 308
E3 ubiquitin-protein ligase parkin PARK2 Tbio Enzyme -2.96983 955.5 485