Development Level

Tbio 156 | 11,445
Tdark 31 | 6,588
Tchem 15 | 1,598
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 9 | 499
abnormal behavior 6 | 298
abnormal embryo size 6 | 220
decreased bone mineral content 5 | 151
decreased grip strength 5 | 116
decreased bone mineral density 4 | 126
decreased circulating glucose ... 4 | 126
decreased lean body mass 4 | 135
decreased startle reflex 4 | 75
decreased vertical activity 4 | 208
embryonic growth retardation 4 | 106
increased circulating alkaline... 4 | 122
increased total body fat amoun... 4 | 134
abnormal bone mineralization 3 | 38
abnormal bone structure 3 | 187
decreased body length 3 | 101
decreased body weight 3 | 161
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased circulating HDL chol... 3 | 80
increased circulating triglyce... 3 | 42
increased mean corpuscular vol... 3 | 92
increased startle reflex 3 | 112
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal coat appearance 2 | 31
abnormal heart morphology 2 | 162
anophthalmia 2 | 33
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating total pr... 2 | 49
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
edema 2 | 59
enlarged heart 2 | 210
enlarged spleen 2 | 41
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating calcium ... 2 | 34
increased circulating choleste... 2 | 66
increased circulating glucose ... 2 | 24
increased circulating phosphat... 2 | 26
increased heart weight 2 | 62
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
male infertility 2 | 123
small thymus 2 | 16
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal esophagus morphology 1 | 5
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal joint morphology 1 | 23
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spine curvature 1 | 9
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
microphthalmia 1 | 26
prenatal lethality 1 | 28
shortened PQ interval 1 | 7
small spleen 1 | 19
syndactyly 1 | 23
tremors 1 | 39
trunk curl 1 | 16

Disease

ovarian cancer 149 | 8,520
Carcinoma 114 | 11,493
osteosarcoma 103 | 7,950
glioblastoma 87 | 5,792
psoriasis 83 | 6,694
medulloblastoma, large-cell 79 | 6,241
lung cancer 73 | 4,740
atypical teratoid / rhabdoid tumor 69 | 5,112
Multiple myeloma 54 | 1,332
ependymoma 51 | 4,679
Cancer 46 | 2,499
Breast cancer 44 | 3,578
adult high grade glioma 43 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
group 3 medulloblastoma 39 | 4,104
malignant mesothelioma 37 | 3,232
non-small cell lung cancer 33 | 2,890
primitive neuroectodermal tumor 32 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
oligodendroglioma 31 | 2,850
astrocytic glioma 30 | 2,597
Kidney cancer 27 | 2,613
lung adenocarcinoma 27 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Astrocytoma, Pilocytic 24 | 3,081
Pick disease 24 | 1,894
diabetes mellitus 24 | 1,728
group 4 medulloblastoma 23 | 1,855
pancreatic cancer 23 | 2,398
subependymal giant cell astrocytoma 23 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
invasive ductal carcinoma 21 | 2,951
adrenocortical carcinoma 20 | 1,428
tuberculosis 20 | 2,010
dermatomyositis 19 | 966
Waldenstrons macroglobulinemia 18 | 765
spina bifida 18 | 1,074
HIV Infections 17 | 102
Schizophrenia 16 | 1,160
acute quadriplegic myopathy 16 | 1,158
astrocytoma 16 | 1,146
ulcerative colitis 16 | 1,819
Alzheimer's disease 15 | 658
Rheumatoid arthritis 15 | 1,191
juvenile dermatomyositis 15 | 1,187
Autosomal recessive predisposition 14 | 1,442
Intellectual disability 14 | 1,016
ductal carcinoma in situ 14 | 1,745
esophageal adenocarcinoma 14 | 737
medulloblastoma 14 | 720
non primary Sjogren syndrome sicca 14 | 891
Parkinson's disease 13 | 392
lung carcinoma 13 | 2,843
pituitary cancer 13 | 1,972
interstitial cystitis 12 | 2,312
Endometriosis 11 | 540
acute myeloid leukemia 11 | 783
breast carcinoma 11 | 1,638
colon cancer 11 | 1,478
Prostatic Neoplasms 10 | 495
gastric carcinoma 10 | 807
Liver Cirrhosis, Experimental 9 | 769
Neurodegenerative disease 9 | 414
hepatocellular carcinoma 9 | 547
progressive supranuclear palsy 9 | 676
Atopic dermatitis 8 | 952
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Obesity 8 | 678
Poor school performance 8 | 645
Stomach Neoplasms 8 | 300
cutaneous lupus erythematosus 8 | 1,057
primary pancreatic ductal adenocarcinoma 8 | 1,109
sonic hedgehog group medulloblastoma 8 | 467
Autistic Disorder 7 | 364
Breast Neoplasms 7 | 445
Cockayne syndrome 7 | 60
Depressive disorder 7 | 409
Liver cancer 7 | 604
Mammary Neoplasms 7 | 425
Osteoporosis 7 | 363
Stevens-Johnson syndrome 7 | 92
Vascular disease 7 | 319
active Crohn's disease 7 | 922
nasopharyngeal carcinoma 7 | 1,058
primary Sjogren syndrome 7 | 735
tuberculosis and treatment for 6 months 7 | 409
Bipolar Disorder 6 | 666
Carcinoma, Hepatocellular 6 | 228
Cognitive delay 6 | 608
Endometrial cancer 6 | 311
Global developmental delay 6 | 608
Liver carcinoma 6 | 240
Mental Depression 6 | 333
Mental and motor retardation 6 | 608
Small head 6 | 374
cystic fibrosis 6 | 1,696
pediatric high grade glioma 6 | 1,064

Tissue

Endocrine System 209 | 18,159
Female tissues 208 | 17,400
Blood and immune system 207 | 16,909
Digestive Tract 207 | 17,369
Male tissues 207 | 17,142
Urinary Tract 206 | 16,678
Liver and Pancreas 205 | 16,750
Nervous System 205 | 16,725
Respiratory system 205 | 16,393
Skin and soft tissues 205 | 17,230
Cardiovascular System 201 | 15,192

Target Family

Non-IDG 105 | 12,091
Enzyme 90 | 4,145
Transcription Factor 6 | 1,400
Kinase 5 | 634
Epigenetic 3 | 242
TF/Epigenetic 1 | 38

GO Process

proteasome-mediated ubiquitin-... 210 | 210
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
BTB/POZ domain-containing protein KCTD5 KCTD5 Tbio Non-IDG -1.70628 50.2 52
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
RING finger protein 222 RNF222 Tdark Non-IDG 0.00000 4
PEST proteolytic signal-containing nuclear protein PCNP Tbio Non-IDG -1.30410 18.1 110
E3 ubiquitin-protein ligase RNF139 RNF139 Tbio Enzyme -1.17169 16.6 133
Glucose-induced degradation protein 4 homolog GID4 Tbio Non-IDG -0.86041 7.07 65
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427