Development Level

Tclin 32 | 613
Tbio 24 | 11,445
Tchem 13 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 16 | 99

IMPC Phenotype

abnormal behavior 5 | 298
preweaning lethality, complete... 4 | 979
hyperactivity 3 | 148
increased bone mineral content 3 | 108
abnormal behavioral response t... 2 | 66
abnormal epididymis morphology 2 | 42
decreased body weight 2 | 161
decreased hemoglobin content 2 | 68
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
impaired glucose tolerance 2 | 75
increased mean platelet volume 2 | 45
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating chloride... 1 | 30
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating total pr... 1 | 28
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10
tremors 1 | 39

Disease

Carcinoma 55 | 11,493
adult high grade glioma 35 | 3,801
ependymoma 35 | 4,679
glioblastoma 35 | 5,792
medulloblastoma, large-cell 35 | 6,241
atypical teratoid / rhabdoid tumor 32 | 5,112
psoriasis 28 | 6,694
group 3 medulloblastoma 26 | 4,104
primitive neuroectodermal tumor 26 | 3,035
Multiple Sclerosis 25 | 540
lung cancer 25 | 4,740
ovarian cancer 25 | 8,520
Astrocytoma, Pilocytic 23 | 3,081
Eaton-Lambert syndrome 22 | 40
oligodendroglioma 22 | 2,850
osteosarcoma 22 | 7,950
astrocytic glioma 20 | 2,597
Kidney cancer 19 | 2,613
subependymal giant cell astrocytoma 18 | 2,287
Epilepsy 16 | 792
malignant mesothelioma 16 | 3,232
lung carcinoma 15 | 2,843
pituitary cancer 15 | 1,972
interstitial cystitis 14 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
lung adenocarcinoma 14 | 2,716
Breast cancer 13 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
Intellectual disability 12 | 1,016
invasive ductal carcinoma 12 | 2,951
pancreatic cancer 12 | 2,398
Hypertension 11 | 396
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
Seizures 10 | 596
non-small cell lung cancer 10 | 2,890
Atrial Fibrillation 9 | 124
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Schizophrenia 8 | 1,160
cystic fibrosis 8 | 1,696
gastric carcinoma 8 | 807
Episodic ataxia 7 | 22
Hyperaldosteronism 7 | 35
Hypertensive disease 7 | 292
Pick disease 7 | 1,894
adrenocortical carcinoma 7 | 1,428
ulcerative colitis 7 | 1,819
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
Cerebellar Ataxia 6 | 304
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Heart disease 6 | 306
Hypokalemia 6 | 52
Long QT syndrome 6 | 39
Mental and motor retardation 6 | 608
chronic rhinosinusitis 6 | 512
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Birk-Barel syndrome 5 | 8
Down syndrome 5 | 499
Failure to gain weight 5 | 365
Pediatric failure to thrive 5 | 365
active ulcerative colitis 5 | 764
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
primary pancreatic ductal adenocarcinoma 5 | 1,109
sonic hedgehog group medulloblastoma 5 | 467
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 4 | 21
Autistic Disorder 4 | 364
Bipolar Disorder 4 | 666
Bushy eyebrows 4 | 49
Byzanthine arch palate 4 | 194
Congestive heart failure 4 | 113
Conn's syndrome 4 | 22
Diarrhea 4 | 253
Endometriosis 4 | 540
Familial atrial fibrillation 4 | 23
Infantile onset 4 | 238
Leber congenital amaurosis 16 4 | 5
Long philtrum 4 | 137
Melanoma 4 | 711
Muscle hypotonia 4 | 571
Parkinson's disease 4 | 392
Paroxysmal atrial fibrillation 4 | 14
Patent ductus arteriosus 4 | 90
Polyhydramnios 4 | 108
Schnyder Corneal Dystrophy 4 | 23
Small head 4 | 374
active Crohn's disease 4 | 922
cutaneous lupus erythematosus 4 | 1,057
nephrosclerosis 4 | 333
progressive supranuclear palsy 4 | 676
Vascular disease 3 | 319
astrocytoma 3 | 1,146
fibroadenoma 3 | 559

Tissue

Endocrine System 70 | 18,159
Nervous System 68 | 16,725
Digestive Tract 67 | 17,369
Female tissues 66 | 17,400
Skin and soft tissues 65 | 17,230
Male tissues 64 | 17,142
Liver and Pancreas 63 | 16,750
Urinary Tract 62 | 16,678
Blood and immune system 60 | 16,909
Respiratory system 59 | 16,393
Cardiovascular System 53 | 15,192

Target Family

Ion Channel 57 | 344
Transporter 6 | 473
Non-IDG 5 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

GO Process

potassium ion transport 71 | 71
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Potassium voltage-gated channel subfamily H member 3 KCNH3 Tclin Ion Channel -1.07866 11.8 67
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Calcium-activated potassium channel subunit beta-4 KCNMB4 Tbio Ion Channel -0.98233 8.05 132
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
FXYD domain-containing ion transport regulator 3 FXYD3 Tbio Ion Channel -1.78093 58.4 76
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162