Development Level

Tclin 35 | 613
Tbio 19 | 11,445
Tchem 10 | 1,598
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 11 | 99

IMPC Phenotype

abnormal behavior 3 | 298
hyperactivity 3 | 148
abnormal heart morphology 2 | 162
decreased erythrocyte cell num... 2 | 62
decreased hemoglobin content 2 | 68
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased mean corpuscular vol... 2 | 92
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal gait 1 | 69
abnormal heart shape 1 | 5
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
increased bone mineral content 1 | 108
increased circulating magnesiu... 1 | 10
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
kyphosis 1 | 5
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 55 | 11,493
ependymoma 30 | 4,679
medulloblastoma, large-cell 28 | 6,241
glioblastoma 27 | 5,792
Eaton-Lambert syndrome 26 | 40
Multiple Sclerosis 26 | 540
Kidney cancer 25 | 2,613
atypical teratoid / rhabdoid tumor 24 | 5,112
Astrocytoma, Pilocytic 22 | 3,081
adult high grade glioma 22 | 3,801
primitive neuroectodermal tumor 22 | 3,035
group 3 medulloblastoma 19 | 4,104
psoriasis 19 | 6,694
oligodendroglioma 17 | 2,850
astrocytic glioma 16 | 2,597
ovarian cancer 16 | 8,520
osteosarcoma 15 | 7,950
Epilepsy 14 | 792
lung cancer 13 | 4,740
Atrial Fibrillation 12 | 124
Intellectual disability 11 | 1,016
Long QT syndrome 11 | 39
invasive ductal carcinoma 11 | 2,951
malignant mesothelioma 11 | 3,232
subependymal giant cell astrocytoma 11 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung carcinoma 10 | 2,843
pituitary cancer 10 | 1,972
Breast cancer 9 | 3,578
Heart disease 9 | 306
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Muscle hypotonia 8 | 571
Pick disease 8 | 1,894
Seizures 8 | 596
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Episodic ataxia 7 | 22
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
Brugada syndrome 6 | 29
Melanoma 6 | 711
Metabolic acidosis 6 | 90
Neurodegenerative disease 6 | 414
Paroxysmal atrial fibrillation 6 | 14
Schizophrenia 6 | 1,160
Skin cancer 6 | 469
fibroadenoma 6 | 559
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 5 | 21
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Familial atrial fibrillation 5 | 23
Global developmental delay 5 | 608
Liver cancer 5 | 604
Mental and motor retardation 5 | 608
Prolonged QT interval 5 | 15
Short QT syndrome 5 | 12
Syncope 5 | 22
colon cancer 5 | 1,478
pancreatic cancer 5 | 2,398
sonic hedgehog group medulloblastoma 5 | 467
tuberculosis 5 | 2,010
Atrioventricular block 4 | 35
Birk-Barel syndrome 4 | 8
Cancer 4 | 2,499
Cardiac Arrhythmia 4 | 103
Cardiac arrest 4 | 36
Cardiomyopathy 4 | 116
Catecholaminergic polymorphic ventricular tachycardia 4 | 12
Diarrhea 4 | 253
Dull intelligence 4 | 645
Heart conduction disease 4 | 83
Hypertension 4 | 396
Infantile onset 4 | 238
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Myoclonus 4 | 74
Poor school performance 4 | 645
Romano-Ward Syndrome 4 | 12
Sudden Cardiac Death 4 | 29
Timothy syndrome 4 | 11
Torsades de Pointes 4 | 8
Type 2 diabetes mellitus 4 | 272
Ventricular Fibrillation 4 | 17
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
progressive supranuclear palsy 4 | 676
ulcerative colitis 4 | 1,819
Bipolar Disorder 3 | 666
Byzanthine arch palate 3 | 194
Depressive disorder 3 | 409
Hepatomegaly 3 | 285
Vascular disease 3 | 319
active Crohn's disease 3 | 922
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 66 | 18,159
Digestive Tract 62 | 17,369
Female tissues 62 | 17,400
Nervous System 61 | 16,725
Male tissues 59 | 17,142
Skin and soft tissues 59 | 17,230
Liver and Pancreas 55 | 16,750
Respiratory system 54 | 16,393
Urinary Tract 54 | 16,678
Blood and immune system 51 | 16,909
Cardiovascular System 47 | 15,192

Target Family

Ion Channel 53 | 344
Transporter 11 | 473
Non-IDG 2 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408

GO Process

potassium ion transmembrane tr... 68 | 68
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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