Development Level

Tbio 13 | 11,651
Tclin 8 | 612
Tchem 2 | 1,388
Tdark 2 | 6,593

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
hyperactivity 2 | 148
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean platelet volume 1 | 25
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating magnesiu... 1 | 10
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
limb grasping 1 | 41
tremors 1 | 39

Disease

Carcinoma 18 | 11,493
medulloblastoma, large-cell 14 | 6,241
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
psoriasis 12 | 6,694
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
primitive neuroectodermal tumor 11 | 3,035
Atrial Fibrillation 10 | 124
ependymoma 10 | 4,679
ovarian cancer 10 | 8,520
subependymal giant cell astrocytoma 10 | 2,287
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
Epilepsy 8 | 792
lung cancer 8 | 4,740
Breast cancer 7 | 3,578
Congestive heart failure 7 | 113
Chronic heart failure 6 | 46
Intellectual disability 6 | 1,016
Poisoning by digitalis glycoside 6 | 8
Schnyder Corneal Dystrophy 6 | 23
Seizures 6 | 596
astrocytic glioma 6 | 2,597
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Pick disease 5 | 1,894
Poor school performance 5 | 645
gastric carcinoma 5 | 807
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
osteosarcoma 5 | 7,950
Bipolar Disorder 4 | 666
Failure to gain weight 4 | 365
Hyperaldosteronism 4 | 35
Hypertension 4 | 396
Hypertensive disease 4 | 292
Hypokalemia 4 | 52
Leber congenital amaurosis 16 4 | 5
Long QT syndrome 4 | 39
Pediatric failure to thrive 4 | 365
Small head 4 | 374
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
nephrosclerosis 4 | 333
non-small cell lung cancer 4 | 2,890
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 3 | 21
Acquired scoliosis 3 | 281
Anteverted nostril 3 | 191
Big calvaria 3 | 147
Broad flat nasal bridge 3 | 236
Byzanthine arch palate 3 | 194
Cerebellar Ataxia 3 | 304
Curvature of spine 3 | 282
Delayed bone age 3 | 136
Depressive disorder 3 | 409
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Familial atrial fibrillation 3 | 23
Hemiplegia and hemiparesis 3 | 38
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Kidney cancer 3 | 2,613
Long philtrum 3 | 137
Low anterior hairline 3 | 30
Nasal bridge wide 3 | 236
Nystagmus 3 | 317
Orbital separation excessive 3 | 244
Pain agnosia 3 | 104
Parkinson's disease 3 | 392
Paroxysmal atrial fibrillation 3 | 14
Prolonged QT interval 3 | 15
Syncope 3 | 22
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
diabetes mellitus 3 | 1,728
mucosa-associated lymphoid tissue lymphoma 3 | 484
Alopecia 2 | 115
Cardiac Arrhythmia 2 | 103
Cardiomyopathy 2 | 116
Fever 2 | 138
Heart failure 2 | 162
Long eyelashes 2 | 37
Osteoporosis 2 | 363
Sensorineural hearing loss 2 | 106

Tissue

Endocrine System 25 | 18,159
Nervous System 24 | 16,725
Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Female tissues 23 | 17,400
Skin and soft tissues 23 | 17,230
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 21 | 16,393
Urinary Tract 21 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Ion Channel 17 | 344
Transporter 8 | 473

GO Process

potassium ion import 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily E member 2 KCNE2 Tbio Ion Channel -2.00780 91.4 120
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.36427 23.9 176
ATP-sensitive inward rectifier potassium channel 10 KCNJ10 Tbio Ion Channel -2.43730 273.3 158
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.10090 13.3 226
G protein-activated inward rectifier potassium channel 2 KCNJ6 Tbio Ion Channel -2.28200 194.3 215
Inward rectifier potassium channel 4 KCNJ4 Tchem Ion Channel -1.91723 84.9 205
Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1 Tclin Transporter -1.40091 23.3 207
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tbio Ion Channel -2.34432 217.2 267
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.12480 136.2 116
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.24223 170.0 132