Development Level

Tbio 254 | 11,445
Tdark 61 | 6,588
Tchem 32 | 1,598
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 19 | 979
preweaning lethality, incomple... 14 | 499
abnormal seminal vesicle morph... 7 | 114
abnormal behavior 6 | 298
abnormal embryo size 5 | 220
decreased circulating choleste... 5 | 93
decreased circulating total pr... 5 | 49
decreased hemoglobin content 5 | 68
decreased vertical activity 5 | 208
enlarged heart 5 | 210
short tibia 5 | 97
abnormal heart morphology 4 | 162
abnormal tooth morphology 4 | 24
decreased body weight 4 | 161
decreased bone mineral content 4 | 151
decreased circulating glucose ... 4 | 126
decreased circulating iron lev... 4 | 32
decreased erythrocyte cell num... 4 | 62
decreased mean corpuscular hem... 4 | 50
decreased total body fat amoun... 4 | 207
embryonic lethality prior to o... 4 | 239
increased blood urea nitrogen ... 4 | 48
abnormal bone structure 3 | 187
abnormal sleep behavior 3 | 70
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating creatini... 3 | 39
decreased circulating serum al... 3 | 82
decreased hematocrit 3 | 46
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating creatini... 3 | 38
increased circulating potassiu... 3 | 29
increased circulating triglyce... 3 | 42
increased erythrocyte cell num... 3 | 39
increased mean corpuscular hem... 3 | 36
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
male infertility 3 | 123
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
abnormal pericardium morpholog... 2 | 26
abnormal spleen morphology 2 | 55
abnormal tail morphology 2 | 25
abnormal urinary bladder morph... 2 | 11
decreased basophil cell number 2 | 16
decreased cardiac muscle contr... 2 | 11
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating chloride... 2 | 30
decreased circulating fructosa... 2 | 30
decreased circulating triglyce... 2 | 79
decreased heart rate 2 | 18
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
dilated heart left ventricle 2 | 11
enlarged spleen 2 | 41
female infertility 2 | 60
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating bilirubi... 2 | 16
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
prolonged ST segment 2 | 36
small superior vagus ganglion 2 | 74
syndactyly 2 | 23
thrombocytosis 2 | 27
abnormal craniofacial morpholo... 1 | 33
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
increased startle reflex 1 | 112

Disease

Carcinoma 218 | 11,493
ovarian cancer 206 | 8,520
osteosarcoma 161 | 7,950
psoriasis 153 | 6,694
medulloblastoma, large-cell 135 | 6,241
glioblastoma 131 | 5,792
atypical teratoid / rhabdoid tumor 119 | 5,112
lung cancer 115 | 4,740
ependymoma 99 | 4,679
Breast cancer 86 | 3,578
malignant mesothelioma 83 | 3,232
Cancer 78 | 2,499
adult high grade glioma 77 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 68 | 3,291
Astrocytoma, Pilocytic 65 | 3,081
invasive ductal carcinoma 64 | 2,951
pancreatic cancer 63 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 62 | 2,989
lung carcinoma 62 | 2,843
Multiple myeloma 61 | 1,332
group 3 medulloblastoma 61 | 4,104
non-small cell lung cancer 61 | 2,890
primitive neuroectodermal tumor 61 | 3,035
oligodendroglioma 58 | 2,850
diabetes mellitus 55 | 1,728
tuberculosis 54 | 2,010
astrocytic glioma 52 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 50 | 1,962
group 4 medulloblastoma 49 | 1,855
lung adenocarcinoma 49 | 2,716
pituitary cancer 46 | 1,972
subependymal giant cell astrocytoma 46 | 2,287
Kidney cancer 43 | 2,613
acute quadriplegic myopathy 40 | 1,158
cystic fibrosis 40 | 1,696
juvenile dermatomyositis 40 | 1,187
ulcerative colitis 39 | 1,819
Autosomal recessive predisposition 37 | 1,442
adrenocortical carcinoma 37 | 1,428
breast carcinoma 36 | 1,638
Pick disease 35 | 1,894
dermatomyositis 35 | 966
interstitial cystitis 34 | 2,312
primary pancreatic ductal adenocarcinoma 34 | 1,109
Rheumatoid arthritis 32 | 1,191
ductal carcinoma in situ 32 | 1,745
gastric carcinoma 30 | 807
Duchenne muscular dystrophy 29 | 601
Waldenstrons macroglobulinemia 28 | 765
astrocytoma 28 | 1,146
pediatric high grade glioma 26 | 1,064
autosomal dominant Emery-Dreifuss muscular dystrophy 25 | 510
non primary Sjogren syndrome sicca 25 | 891
colon cancer 24 | 1,478
nasopharyngeal carcinoma 24 | 1,058
Alzheimer's disease 22 | 658
Kidney disease 22 | 430
Liver Cirrhosis, Experimental 22 | 769
active Crohn's disease 22 | 922
esophageal adenocarcinoma 22 | 737
Atherosclerosis 21 | 291
HIV Infections 20 | 102
Hypertension 20 | 396
Obesity 20 | 678
Schizophrenia 19 | 1,160
Atopic dermatitis 18 | 952
Liver disease 18 | 237
sonic hedgehog group medulloblastoma 18 | 467
Coronary artery disease 17 | 268
Osteoporosis 17 | 363
aldosterone-producing adenoma 17 | 665
cutaneous lupus erythematosus 17 | 1,057
medulloblastoma 17 | 720
Hypertensive disease 16 | 292
Parkinson's disease 16 | 392
Vascular disease 16 | 319
active ulcerative colitis 16 | 764
hepatocellular carcinoma 16 | 547
Breast Neoplasms 15 | 445
Heart disease 15 | 306
Neurodegenerative disease 15 | 414
Prostatic Neoplasms 15 | 495
spina bifida 15 | 1,074
Bipolar Disorder 14 | 666
Liver Cirrhosis 14 | 181
Mammary Neoplasms 14 | 425
Melanoma 14 | 711
interstitial lung disease 14 | 298
sarcoidosis 14 | 370
Amyotrophic lateral sclerosis 13 | 451
Becker muscular dystrophy 13 | 191
Cerebrovascular disease 13 | 238
Down syndrome 13 | 499
Endometriosis 13 | 540
Epilepsy 13 | 792
Hepatomegaly 13 | 285
Intellectual disability 13 | 1,016
limb girdle muscular dystrophy 2A 13 | 213
primary Sjogren syndrome 13 | 735

Tissue

Endocrine System 353 | 18,159
Female tissues 345 | 17,400
Male tissues 344 | 17,142
Skin and soft tissues 344 | 17,230
Digestive Tract 343 | 17,369
Liver and Pancreas 341 | 16,750
Urinary Tract 340 | 16,678
Blood and immune system 337 | 16,909
Nervous System 337 | 16,725
Respiratory system 335 | 16,393
Cardiovascular System 327 | 15,192

Target Family

Non-IDG 257 | 12,091
Enzyme 94 | 4,145
Transcription Factor 3 | 1,400
Kinase 2 | 634

GO Process

post-translational protein mod... 356 | 356
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ankyrin repeat and SOCS box protein 5 ASB5 Tdark Non-IDG 0.03 1.06 75
WD repeat and SOCS box-containing protein 1 WSB1 Tbio Non-IDG -1.13058 13.3 63
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
DDB1- and CUL4-associated factor 16 DCAF16 Tdark Non-IDG 0.08 0.54 13
Ankyrin repeat and SOCS box protein 11 ASB11 Tdark Non-IDG 0.42 0.27 87
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Ankyrin repeat and SOCS box protein 12 ASB12 Tdark Non-IDG 0.00000 52
F-box/LRR-repeat protein 12 FBXL12 Tdark Non-IDG -0.43169 3.45 132
Ankyrin repeat and SOCS box protein 17 ASB17 Tdark Non-IDG -0.64836 4.22 120
Ankyrin repeat and SOCS box protein 15 ASB15 Tdark Non-IDG -0.67669 6.19 6