Development Level

Tbio 39 | 10,625
Tchem 18 | 1,890
Tclin 7 | 602
Tdark 6 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 2 | 260
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal tail morphology 1 | 17
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased total body fat amoun... 1 | 186
edema 1 | 11
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased circulating LDL chol... 1 | 15
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
respiratory system phenotype 1 | 2
small epididymis 1 | 3
trunk curl 1 | 15

Disease

osteosarcoma 42 | 7,933
ovarian cancer 41 | 8,484
medulloblastoma, large-cell 35 | 6,234
psoriasis 30 | 6,685
glioblastoma 28 | 5,572
lung cancer 23 | 4,466
Breast cancer 21 | 3,094
Carcinoma 21 | 2,147
Cancer 20 | 2,346
atypical teratoid / rhabdoid tumor 20 | 4,369
malignant mesothelioma 19 | 3,162
invasive ductal carcinoma 18 | 2,950
lung carcinoma 18 | 2,844
pituitary cancer 17 | 1,972
primitive neuroectodermal tumor 17 | 3,031
pancreatic cancer 16 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
subependymal giant cell astrocytoma 16 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
pilocytic astrocytoma 15 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
oligodendroglioma 14 | 2,849
pediatric high grade glioma 14 | 2,712
spina bifida 14 | 1,064
cystic fibrosis 13 | 1,665
group 4 medulloblastoma 13 | 1,875
non-small cell lung cancer 13 | 2,798
ulcerative colitis 13 | 2,087
colon cancer 12 | 1,475
Pick disease 11 | 1,893
Rheumatoid Arthritis 11 | 1,160
ependymoma 11 | 2,514
group 3 medulloblastoma 11 | 2,254
lung adenocarcinoma 11 | 2,713
adult high grade glioma 10 | 2,148
astrocytic glioma 10 | 2,241
astrocytoma 10 | 1,493
Intellectual disability 9 | 573
acute quadriplegic myopathy 9 | 1,157
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,299
primary pancreatic ductal adenocarcinoma 9 | 1,271
Epilepsy 8 | 346
Multiple myeloma 8 | 1,327
adrenocortical carcinoma 8 | 1,427
breast carcinoma 8 | 1,614
juvenile dermatomyositis 8 | 1,189
posterior fossa group A ependymoma 8 | 1,511
Colorectal Neoplasms 7 | 217
Craniofacial Abnormalities 7 | 147
Obesity 7 | 616
acute myeloid leukemia 7 | 780
cutaneous lupus erythematosus 7 | 1,056
diabetes mellitus 7 | 1,663
posterior fossa group B ependymoma 7 | 1,530
sonic hedgehog group medulloblastoma 7 | 1,482
Waldenstrons macroglobulinemia 6 | 765
atypical teratoid/rhabdoid tumor 6 | 1,095
chronic rhinosinusitis 6 | 512
urothelial carcinoma 6 | 318
Alzheimer's disease 5 | 644
Autistic Disorder 5 | 320
Down syndrome 5 | 548
Kidney disease 5 | 396
Parkinson's disease 5 | 364
Prostatic Neoplasms 5 | 471
Schizophrenia 5 | 501
active ulcerative colitis 5 | 477
aldosterone-producing adenoma 5 | 664
non primary Sjogren syndrome sicca 5 | 840
pancreatic carcinoma 5 | 567
primary Sjogren syndrome 5 | 789
tuberculosis 5 | 1,557
tuberculosis and treatment for 6 months 5 | 686
Bipolar Disorder 4 | 266
Cleft palate 4 | 125
Hypertension 4 | 287
Nerve Degeneration 4 | 73
Neurodegenerative disease 4 | 383
Precursor Cell Lymphoblastic Leukemia Lymphoma 4 | 42
Prostate cancer 4 | 172
fibroadenoma 4 | 557
gastric cancer 4 | 430
gastric carcinoma 4 | 832
inflammatory breast cancer 4 | 404
medulloblastoma 4 | 1,524
Adenoma 3 | 165
Amyotrophic Lateral Sclerosis 3 | 431
Atopic dermatitis 3 | 944
Craniosynostosis 3 | 47
Duchenne muscular dystrophy 3 | 602
Heart disease 3 | 279
Peripheral Neuropathy 3 | 303
dermatomyositis 3 | 933
glioblastoma multiforme 3 | 347
hepatocellular carcinoma 3 | 532
mucosa-associated lymphoid tissue lymphoma 3 | 480
nephrosclerosis 3 | 329
progressive supranuclear palsy 3 | 674

Tissue

Blood and immune system 70 | 17,995
Digestive Tract 69 | 18,473
Endocrine System 69 | 18,512
Female tissues 69 | 18,647
Male tissues 69 | 17,969
Nervous System 69 | 18,561
Respiratory system 69 | 17,484
Skin and soft tissues 69 | 18,115
Urinary Tract 69 | 18,444
Cardiovascular System 68 | 17,958
Liver and Pancreas 68 | 18,136

Target Family

Non-IDG 25 | 11,971
Enzyme 15 | 4,146
Transcription Factor 13 | 1,400
Kinase 6 | 634
Epigenetic 3 | 242
Ion Channel 3 | 341
TF/Epigenetic 2 | 38
Transporter 2 | 473
Nuclear Receptor 1 | 48

GO Process

post-embryonic development 70 | 70
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.63360 51.0 128
Signal peptide, CUB and EGF-like domain-containing protein 1 SCUBE1 Tbio Non-IDG -1.25952 24.9 65
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.16723 1539.5 438
Selenoprotein P SELENOP Tbio Non-IDG -2.42408 315.2 94
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.48654 293.0 56
Homeobox protein aristaless-like 4 ALX4 Tbio Transcription Factor -1.72143 58.9 149
Forkhead box protein P2 FOXP2 Tbio Transcription Factor -2.45964 292.2 303
Methylcytosine dioxygenase TET2 TET2 Tbio Enzyme -3.23763 1705.1 225
Cysteine/serine-rich nuclear protein 1 CSRNP1 Tbio Non-IDG -0.77582 7.95 82