Development Level

Tchem 4 | 1,890
Tbio 3 | 10,625
Tclin 1 | 602

IMPC Phenotype

decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased lean body mass 1 | 195
embryonic lethality prior to t... 1 | 187
impaired glucose tolerance 1 | 52
limb grasping 1 | 35
preweaning lethality, complete... 1 | 633

Disease

osteosarcoma 7 | 7,933
psoriasis 6 | 6,685
interstitial cystitis 5 | 2,299
lung cancer 5 | 4,473
Cancer 4 | 2,346
lung carcinoma 4 | 2,844
ovarian cancer 4 | 8,491
Breast cancer 3 | 3,098
cutaneous lupus erythematosus 3 | 1,056
invasive ductal carcinoma 3 | 2,950
non-small cell lung cancer 3 | 2,798
primary Sjogren syndrome 3 | 788
Carcinoma 2 | 2,147
Down syndrome 2 | 548
Severe Combined Immunodeficiency 2 | 46
astrocytoma 2 | 1,493
glioblastoma 2 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
spina bifida 2 | 1,064
Adenocarcinoma 1 | 115
Adenocarcinoma Of Esophagus 1 | 14
Adenocarcinoma of lung (disorder) 1 | 48
Agnathia-otocephaly complex 1 | 8
Alobar Holoprosencephaly 1 | 14
Ameloblastoma 1 | 25
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Basal cell carcinoma of skin 1 | 2
Biliary cirrhosis 1 | 33
CMM1 1 | 5
Carcinoma of pancreas 1 | 5
Choanal atresia 1 | 19
Chromosome 13q14 deletion syndrome 1 | 7
Cleft Lip 1 | 91
Cleft palate 1 | 125
Coloboma 1 | 52
Coloboma, ocular, autosomal dominant 1 | 6
Congenital ocular coloboma (disorder) 1 | 12
Cowden disease 1 | 20
Dermatitis, Allergic Contact 1 | 66
Encephalitis 1 | 54
Esophageal atresia 1 | 25
Eye Abnormalities 1 | 15
Fetal alcohol syndrome 1 | 10
HIV Infections 1 | 99
Hamman-Rich syndrome 1 | 35
Heart disease 1 | 279
Holoprosencephaly 1 | 52
Hypertensive disease 1 | 193
Hypoplasia or aplasia of tibia with polydactyly 1 | 2
Hypoplastic tibiae-postaxial polydactyly syndrome 1 | 2
Hypospadias 1 | 65
IGA Glomerulonephritis 1 | 454
Immunologic Deficiency Syndromes 1 | 16
Imperforate anus 1 | 14
Intussusception 1 | 5
Juvenile polyposis syndrome 1 | 7
Kidney cancer 1 | 121
Laurin-Sandrow syndrome 1 | 3
Left Ventricular Hypertrophy 1 | 24
Liver Failure, Acute 1 | 22
Liver diseases 1 | 66
Lobar Holoprosencephaly 1 | 14
Lung Neoplasms 1 | 171
Lymphoma 1 | 57
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 4
Malignant neoplasm of testis 1 | 5
Mammary Neoplasms 1 | 410
Microcephaly 1 | 149
Microphthalmia 1 | 79
Mycobacterium avium complex disease 1 | 11
Neoplastic Syndromes, Hereditary 1 | 48
Neurotoxicity Syndromes 1 | 26
Nevoid basal cell carcinoma syndrome 1 | 9
POLYDACTYLY, PREAXIAL II (disorder) 1 | 2
Pallister-Hall syndrome 1 | 11
Pancreatic Neoplasm 1 | 79
Parkinson's disease 1 | 364
Peutz-Jeghers syndrome 1 | 23
Polydactyly, Preaxial 2 1 | 2
Pre B-cell acute lymphoblastic leukemia 1 | 4
Preaxial polydactyly 2 1 | 2
Renal transplant rejection 1 | 13
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 1 | 14
Secondary Parkinson Disease 1 | 9
Semilobar Holoprosencephaly 1 | 14
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, NK Cell-Negative 1 | 3
Squamous cell carcinoma 1 | 96
Syndactyly, Type IV 1 | 2
T cell deficiency 1 | 7
Testicular germ cell tumor 1 | 23
Tibia, Hypoplasia of, with Polydactyly 1 | 2
VACTERL association 1 | 23
Viral pneumonia 1 | 5
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
atypical teratoid/rhabdoid tumor 1 | 1,095
head and neck cancer 1 | 270
non-small cell lung carcinoma 1 | 413

Tissue

Blood and immune system 8 | 17,994
Cardiovascular System 8 | 17,957
Digestive Tract 8 | 18,472
Endocrine System 8 | 18,511
Female tissues 8 | 18,646
Liver and Pancreas 8 | 18,135
Male tissues 8 | 17,968
Nervous System 8 | 18,560
Respiratory system 8 | 17,483
Skin and soft tissues 8 | 18,114
Urinary Tract 8 | 18,443

Target Family

Non-IDG 4 | 11,969
Kinase 3 | 634
Transcription Factor 1 | 1,400

GO Process

positive thymic T cell selecti... 8 | 8
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.90245 772.4 1327
Dedicator of cytokinesis protein 2 DOCK2 Tbio Non-IDG -1.59429 44.7 105
Serum response factor SRF Tbio Transcription Factor -2.93246 688.5 447
Inositol-trisphosphate 3-kinase B ITPKB Tbio Kinase -1.41899 29.1 141
Sonic hedgehog protein SHH Tchem Non-IDG -3.41018 2672.5 343
HLA class II histocompatibility antigen gamma chain CD74 Tchem Non-IDG -2.41134 272.6 787
T-cell surface glycoprotein CD3 delta chain CD3D Tclin Non-IDG -2.40047 243.4 518
Serine/threonine-protein kinase STK11 STK11 Tchem Kinase -2.91576 899.7 869