Development Level

Tchem 4 | 1,388
Tbio 3 | 11,651
Tclin 1 | 612

IMPC Phenotype

decreased body weight 1 | 161
decreased lean body mass 1 | 135
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 7 | 7,950
Carcinoma 6 | 11,493
psoriasis 6 | 6,694
interstitial cystitis 5 | 2,312
lung cancer 5 | 4,740
Cancer 4 | 2,499
lung carcinoma 4 | 2,843
ovarian cancer 4 | 8,520
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Immunologic Deficiency Syndromes 3 | 113
Kidney cancer 3 | 2,613
cutaneous lupus erythematosus 3 | 1,057
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
primary Sjogren syndrome 3 | 735
Astrocytoma, Pilocytic 2 | 3,081
Diarrhea 2 | 253
Down syndrome 2 | 499
Failure to gain weight 2 | 365
Fetal Alcohol Spectrum Disorders 2 | 13
Fetal alcohol syndrome 2 | 22
Pediatric failure to thrive 2 | 365
Severe combined immunodeficiency 2 | 51
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
pancreatic cancer 2 | 2,398
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Abnormal pigmentation of the oral mucosa 1 | 2
Abnormally small eyeball on both sides 1 | 5
Adenocarcinoma Of Esophagus 1 | 14
Adenocarcinoma of lung (disorder) 1 | 60
Ameloblastoma 1 | 24
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Basal cell carcinoma of skin 1 | 2
Bilateral nanophthalmos 1 | 5
Biliary cirrhosis 1 | 45
Carcinoma of pancreas 1 | 5
Carcinoma, Pancreatic Ductal 1 | 20
Cervix carcinoma 1 | 10
Choanal Atresia 1 | 42
Chromosome 13q14 deletion syndrome 1 | 6
Coloboma 1 | 51
Coloboma, Ocular, Autosomal Dominant 1 | 6
Cowden disease 1 | 18
Eczema 1 | 45
Familial schizencephaly 1 | 4
Frequent Candida infections 1 | 2
Gastrointestinal Hemorrhage 1 | 52
Gastrointestinal carcinoma 1 | 2
Gastrointestinal hamartomatous polyps 1 | 10
Gynecomastia 1 | 64
Hamartomatous polyp 1 | 10
Hamman-Rich syndrome 1 | 34
Hemiparesis 1 | 34
Holoprosencephaly 3 1 | 7
Hypoplastic tibiae-postaxial polydactyly syndrome 1 | 2
Increased risk of pancreatic cancer 1 | 9
Intestinal Polyposis 1 | 6
Intestinal hemorrhage NOS 1 | 2
Intussusception 1 | 5
Iron deficiency anemia 1 | 12
Liver Cirrhosis, Biliary 1 | 33
Lymphoproliferative syndrome 1 | 58
Malignant neoplasm of pancreas 1 | 9
Microphthalmia, Isolated, with Coloboma 1 1 | 8
Microphthalmia, bilateral 1 | 5
Mouth Abnormalities 1 | 14
Multiple lentigines 1 | 10
Myocarditis 1 | 18
Narrow nose 1 | 20
Neoplasms 1 | 63
Neurotoxicity Syndromes 1 | 26
Ovarian Cysts 1 | 41
POLYDACTYLY, PREAXIAL II (disorder) 1 | 2
Panhypogammaglobulinemia 1 | 9
Parkinson Disease, Secondary 1 | 9
Peutz-Jeghers syndrome 1 | 21
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Polydactyly preaxial type 1 1 | 9
Polydactyly, Preaxial 2 1 | 2
Porencephaly 1 | 20
Pre B-cell acute lymphoblastic leukemia 1 | 5
Renal transplant rejection 1 | 13
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 1 | 5
Schizencephaly 1 | 4
Secondary Parkinson Disease 1 | 10
Senile lentigo 1 | 10
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, NK Cell Positive 1 | 5
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, NK Cell-Negative 1 | 3
Smith-Lemli-Opitz syndrome 1 | 9
Syndactyly, Type IV 1 | 2
T cell deficiency 1 | 8
Teratoma 1 | 8
Testicular Germ Cell Tumor 1 | 14
Tibia, Hypoplasia of, with Polydactyly 1 | 2
Viral pneumonia 1 | 5

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 4 | 12,091
Kinase 3 | 634
Transcription Factor 1 | 1,400

GO Process

positive thymic T cell selecti... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
Inositol-trisphosphate 3-kinase B ITPKB Tbio Kinase -1.44569 29.5 168
T-cell surface glycoprotein CD3 delta chain CD3D Tclin Non-IDG -2.41767 251.2 546
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Dedicator of cytokinesis protein 2 DOCK2 Tbio Non-IDG -1.66165 51.5 140
Sonic hedgehog protein SHH Tchem Non-IDG -3.44287 2879.1 383
HLA class II histocompatibility antigen gamma chain CD74 Tchem Non-IDG -2.44232 286.2 1032
Serine/threonine-protein kinase STK11 STK11 Tchem Kinase -2.96288 998.3 959