Development Level

Tbio 26 | 11,651
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating sodium l... 1 | 22
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
fused cornea and lens 1 | 5
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased heart rate 1 | 23
short tibia 1 | 97
shortened RR interval 1 | 17

Disease

ovarian cancer 18 | 8,520
Carcinoma 14 | 11,493
Multiple myeloma 11 | 1,332
lung cancer 11 | 4,740
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Kidney cancer 6 | 2,613
diabetes mellitus 6 | 1,728
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Cockayne syndrome 4 | 60
Hereditary spherocytosis type 5 4 | 12
astrocytoma 4 | 1,146
medulloblastoma, large-cell 4 | 6,241
primitive neuroectodermal tumor 4 | 3,035
Rheumatoid arthritis 3 | 1,191
Wolf-Hirschhorn syndrome 3 | 32
Xeroderma pigmentosum group B 3 | 20
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Acquired immunodeficiency syndrome 2 | 197
Astrocytoma, Pilocytic 2 | 3,081
Cerebellar Ataxia 2 | 304
Claw hand 2 | 26
Cognitive delay 2 | 608
Congenital clubfoot 2 | 109
Congenital myasthenic syndrome 5 2 | 11
Fetal Growth Retardation 2 | 189
Global developmental delay 2 | 608
Hypoplastic mandible condyle 2 | 275
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Mandibular hypoplasia 2 | 275
Mental and motor retardation 2 | 608
Micrognathism 2 | 275
Mixed connective tissue disease 2 | 16
Pick disease 2 | 1,894
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
non primary Sjogren syndrome sicca 2 | 891
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
sarcoidosis 2 | 370
Anxiety 1 | 136
Anxiety disease 1 | 113
Arachnodactyly 1 | 49
Astigmatism 1 | 54
Autosomal recessive limb-girdle muscular dystrophy type 2C 1 | 2
Cerebellar Dysmetria 1 | 56
Chikungunya 1 | 16
Congenital diaphragmatic hernia 1 | 67
Corneal edema 1 | 14
Decreased motor NCV 1 | 22
Deglutition Disorders 1 | 132
Dental abnormalities 1 | 60
Dyspnea 1 | 76
Endometriosis of ovary 1 | 5
Gaucher disease type 3 1 | 67
Heart valve disease 1 | 39
Hemangioma 1 | 69
Hyperkyphosis 1 | 111
Hypodontia 1 | 81
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Keloid 1 | 37
Keratoconus 1 | 113
Kyphoscoliosis deformity of spine 1 | 60
Kyphosis deformity of spine 1 | 114
La Crosse encephalitis 1 | 5
Low posterior hairline 1 | 52
Low serum estradiol levels 1 | 22
Macular degeneration 1 | 65
Mild Mental Retardation 1 | 70
Mood swings 1 | 77
Muscle Cramp 1 | 55
Muscular fasciculation 1 | 22
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Pain 1 | 103
Paralysed 1 | 42
Peripheral demyelination 1 | 16
Polydactyly preaxial type 1 1 | 9
Primary hypogonadism 1 | 37
Tooth Abnormalities 1 | 69

Tissue

Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678

Target Family

Enzyme 14 | 4,145
Non-IDG 12 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

positive regulation of viral t... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription initiation factor IIB GTF2B Tbio Non-IDG -2.63302 410.1 286
DNA-directed RNA polymerase II subunit RPB11-a POLR2J Tbio Enzyme -1.43224 29.3 213
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.77350 60.4 174
Transcription elongation factor SPT4 SUPT4H1 Tbio Non-IDG -1.65513 43.4 92
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
Negative elongation factor B NELFB Tbio Non-IDG -1.16040 16.4 158
DNA-directed RNA polymerase II subunit RPB4 POLR2D Tbio Enzyme -0.53756 3.34 136
General transcription factor IIF subunit 1 GTF2F1 Tbio Non-IDG -1.59873 42.5 176
Negative elongation factor C/D NELFCD Tbio Non-IDG -2.67806 448.8 134
Cyclin-dependent kinase 9 CDK9 Tchem Kinase -3.01545 918.3 372