Development Level

Tbio 43 | 11,445
Tchem 8 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased vertical activity 2 | 208
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased CD4-positive, alpha ... 1 | 4
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 35 | 11,493
ovarian cancer 34 | 8,520
medulloblastoma, large-cell 31 | 6,241
osteosarcoma 29 | 7,950
atypical teratoid / rhabdoid tumor 26 | 5,112
lung cancer 24 | 4,740
glioblastoma 23 | 5,792
psoriasis 23 | 6,694
ependymoma 22 | 4,679
Cancer 20 | 2,499
group 3 medulloblastoma 20 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
primitive neuroectodermal tumor 17 | 3,035
oligodendroglioma 16 | 2,850
Breast cancer 15 | 3,578
adult high grade glioma 15 | 3,801
Multiple myeloma 14 | 1,332
invasive ductal carcinoma 14 | 2,951
malignant mesothelioma 14 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
pancreatic cancer 13 | 2,398
subependymal giant cell astrocytoma 12 | 2,287
Astrocytoma, Pilocytic 11 | 3,081
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung adenocarcinoma 11 | 2,716
astrocytic glioma 10 | 2,597
colon cancer 10 | 1,478
lung carcinoma 10 | 2,843
Pick disease 9 | 1,894
acute quadriplegic myopathy 9 | 1,158
breast carcinoma 9 | 1,638
group 4 medulloblastoma 9 | 1,855
non-small cell lung cancer 9 | 2,890
primary pancreatic ductal adenocarcinoma 9 | 1,109
Amyotrophic lateral sclerosis 8 | 451
Kidney cancer 8 | 2,613
Schizophrenia 8 | 1,160
Vascular disease 8 | 319
dermatomyositis 8 | 966
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,312
ulcerative colitis 8 | 1,819
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
juvenile dermatomyositis 7 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
progressive supranuclear palsy 7 | 676
tuberculosis 7 | 2,010
Alzheimer's disease 6 | 658
Intellectual disability 6 | 1,016
Polycystic ovary syndrome 6 | 360
Stomach Neoplasms 6 | 300
astrocytoma 6 | 1,146
cystic fibrosis 6 | 1,696
mucosa-associated lymphoid tissue lymphoma 6 | 484
Autistic Disorder 5 | 364
Disease Models, Animal 5 | 155
Duchenne muscular dystrophy 5 | 601
Lung Neoplasms 5 | 232
Neoplasm Metastasis 5 | 168
Ovarian Neoplasms 5 | 102
Parkinson's disease 5 | 392
Renal Cell Carcinoma 5 | 214
hepatocellular carcinoma 5 | 547
ovarian neoplasm 5 | 99
Anemia 4 | 365
Carcinoma, Renal Cell 4 | 124
Cleft Palate 4 | 271
Depressive disorder 4 | 409
Hyperalgesia 4 | 83
Hypertension 4 | 396
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Liver Neoplasms, Experimental 4 | 59
Major Depressive Disorder 4 | 301
Mental Depression 4 | 333
Multiple Sclerosis 4 | 540
Neoplasm Invasiveness 4 | 161
Neurodegenerative disease 4 | 414
Obesity 4 | 678
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
Thrombocytopenia 4 | 197
Unipolar Depression 4 | 250
adrenocortical carcinoma 4 | 1,428
esophageal adenocarcinoma 4 | 737
interstitial lung disease 4 | 298
nasopharyngeal carcinoma 4 | 1,058
sarcoidosis 4 | 370
spina bifida 4 | 1,074
Arthritis 3 | 290
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Endometriosis 3 | 540
Prostatic Neoplasms 3 | 495
aldosterone-producing adenoma 3 | 665

Tissue

Endocrine System 55 | 18,159
Blood and immune system 54 | 16,909
Cardiovascular System 54 | 15,192
Digestive Tract 54 | 17,369
Female tissues 54 | 17,400
Liver and Pancreas 54 | 16,750
Male tissues 54 | 17,142
Nervous System 54 | 16,725
Respiratory system 54 | 16,393
Skin and soft tissues 54 | 17,230
Urinary Tract 54 | 16,678

Target Family

Non-IDG 38 | 12,091
Kinase 9 | 634
Enzyme 3 | 4,145
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Transporter 1 | 473

GO Process

positive regulation of transla... 55 | 55
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PAS domain-containing serine/threonine-protein kinase PASK Tbio Kinase -1.01354 12.3 95
BarH-like 2 homeobox protein BARHL2 Tbio Transcription Factor -0.91713 9.51 53
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
60S ribosomal protein L26 RPL26 Tbio Non-IDG -1.66446 44.8 126
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.34679 21.2 88
ATP-binding cassette sub-family F member 1 ABCF1 Tbio Transporter -1.16255 15.7 212
Stress-associated endoplasmic reticulum protein 1 SERP1 Tbio Non-IDG -1.37994 31.0 79
Spliceosome RNA helicase DDX39B DDX39B Tbio Enzyme -1.74494 60.6 182
Protein Niban FAM129A Tbio Non-IDG -1.07686 12.9 159
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363