Development Level

Tbio 8 | 11,651
Tchem 4 | 1,388

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Cancer 8 | 2,499
Vascular disease 7 | 319
diabetes mellitus 7 | 1,728
Breast cancer 6 | 3,578
Carcinoma 6 | 11,493
lung cancer 6 | 4,740
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Obesity 5 | 678
glioblastoma 5 | 5,792
Bipolar Disorder 4 | 666
Carcinoma, Hepatocellular 4 | 228
Fatty Liver 4 | 70
Liver carcinoma 4 | 240
group 3 medulloblastoma 4 | 4,104
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Asbestosis 3 | 20
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Toxic encephalopathy 3 | 141
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
hepatocellular carcinoma 3 | 547
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Bipolar I disorder 2 | 23
Brain Ischemia 2 | 110
Breast Neoplasms 2 | 445
Carcinoma, Non-Small-Cell Lung 2 | 107
Depressive disorder 2 | 409
Diabetes Mellitus, Experimental 2 | 108
Epilepsy 2 | 792
Esophageal Squamous Cell Carcinoma 2 | 77
Eye disease 2 | 62
Fatty liver disease 2 | 103
Female infertility 2 | 30
Gaucher disease type 1 2 | 180
Glioma 2 | 74
Hydrocephalus 2 | 152
Infertility, Female 2 | 28
Keratosis 2 | 37
Kidney disease 2 | 430
Liver disease 2 | 237
Liver neoplasms 2 | 130
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Photodysphoria 2 | 121
Photophobia 2 | 121
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Sarcoma 2 | 62
Seizures 2 | 596
Somatic mutation 2 | 61
Squamous cell carcinoma of esophagus 2 | 77
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung carcinoma 2 | 317
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
ADRENOCORTICAL CARCINOMA, HEREDITARY 1 | 1
Carcinoma of pancreas 1 | 5
Cardiomyopathy, Hypertrophic 1 | 24
Chromosome 17 deletion 1 | 2
Emphysema 1 | 12
Encephalopathy, progressive 1 | 6
Gallbladder Neoplasms 1 | 10
Glioma Susceptibility 1 1 | 5
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Increased gastric cancer 1 | 21
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Li-Fraumeni syndrome 2 1 | 2
Lymphoma, T-Cell 1 | 13
Neoplasm of stomach 1 | 11
Osteogenic Sarcoma 1 | 6
Ovarian epithelial cancer 1 | 10
Papilloma, Choroid Plexus 1 | 1
Progressive brain disease 1 | 6
Pulmonary Disease, Chronic Obstructive 1 | 31
Subacute progressive viral hepatitis 1 | 9
central nervous system cancer 1 | 3
esophageal cancer 1 | 22
lung small cell carcinoma 1 | 4

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Nervous System 12 | 16,725
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192
Male tissues 11 | 17,142
Respiratory system 11 | 16,393

Target Family

Transcription Factor 10 | 1,400
Enzyme 1 | 4,145
Non-IDG 1 | 12,091

GO Process

positive regulation of transcr... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclic AMP-dependent transcription factor ATF-6 beta ATF6B Tbio Transcription Factor -1.03459 8.22 6
Membrane-bound transcription factor site-2 protease MBTPS2 Tbio Enzyme -1.94015 86.1 119
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.35010 2184.4 1074
Cyclic AMP-responsive element-binding protein 3-like protein 1 CREB3L1 Tbio Transcription Factor -1.53171 30.7 215
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Cyclic AMP-responsive element-binding protein 3-like protein 3 CREB3L3 Tbio Transcription Factor -1.51965 41.5 33
Cyclic AMP-dependent transcription factor ATF-3 ATF3 Tbio Transcription Factor -2.67021 520.8 401