Development Level

Tbio 19 | 11,445
Tchem 15 | 1,598

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased circulating glucose ... 2 | 126
increased startle reflex 2 | 112
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal spinal cord morpholog... 1 | 9
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased circulating creatini... 1 | 39
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased total body fat amoun... 1 | 134
increased urine microalbumin l... 1 | 2
male infertility 1 | 123
mammalian phenotype 1 | 17
small testis 1 | 58

Disease

ovarian cancer 29 | 8,520
Carcinoma 26 | 11,493
lung cancer 18 | 4,740
medulloblastoma, large-cell 15 | 6,241
psoriasis 15 | 6,694
group 3 medulloblastoma 14 | 4,104
osteosarcoma 14 | 7,950
Cancer 12 | 2,499
glioblastoma 11 | 5,792
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
dermatomyositis 10 | 966
non-small cell lung cancer 10 | 2,890
Multiple myeloma 9 | 1,332
ependymoma 9 | 4,679
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
Intellectual disability 7 | 1,016
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
oligodendroglioma 7 | 2,850
primitive neuroectodermal tumor 7 | 3,035
Autosomal recessive predisposition 6 | 1,442
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Pick disease 6 | 1,894
Poor school performance 6 | 645
Schizophrenia 6 | 1,160
Stomach Neoplasms 6 | 300
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
Disease Models, Animal 5 | 155
Neurodegenerative disease 5 | 414
Prostatic Neoplasms 5 | 495
Short stature 5 | 531
Small head 5 | 374
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
pancreatic cancer 5 | 2,398
Alopecia 4 | 115
Breast Neoplasms 4 | 445
Cataract 4 | 297
Cognitive delay 4 | 608
Fetal Growth Retardation 4 | 189
Global developmental delay 4 | 608
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Lung Neoplasms 4 | 232
Mammary Neoplasms 4 | 425
Mental and motor retardation 4 | 608
Microcephaly 4 | 166
Nerve Degeneration 4 | 121
Squamous cell carcinoma 4 | 129
Strabismus 4 | 270
Vascular disease 4 | 319
ductal carcinoma in situ 4 | 1,745
pediatric high grade glioma 4 | 1,064
Adenocarcinoma of lung 3 | 142
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Cellular immunodeficiency 3 | 17
Dental caries 3 | 164
Dilated ventricles (finding) 3 | 121
Epilepsy 3 | 792
HIV Infections 3 | 102
Immune system cancer 3 | 140
Infantile onset 3 | 238
Liver cancer 3 | 604
Lymphoid leukemia 3 | 160
Malabsorption 3 | 82
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Neoplasm Invasiveness 3 | 161
Neoplasm Metastasis 3 | 168
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Osteoporosis 3 | 363
Ovarian Neoplasms 3 | 102
Recurrent respiratory infections 3 | 141
Seizures 3 | 596
Skeletal muscle atrophy 3 | 139
Telangiectasia of the skin 3 | 39
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
muscle degeneration 3 | 139
nasopharyngeal carcinoma 3 | 1,058
ovarian neoplasm 3 | 99
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010

Tissue

Blood and immune system 33 | 16,909
Cardiovascular System 33 | 15,192
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678

Target Family

Non-IDG 16 | 12,091
Kinase 12 | 634
Enzyme 5 | 4,145
Transcription Factor 1 | 1,400

GO Process

positive regulation of telomer... 34 | 34
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.26984 173.7 468
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Mitogen-activated protein kinase kinase kinase 4 MAP3K4 Tbio Kinase -1.49704 31.8 244
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
T-complex protein 1 subunit theta CCT8 Tbio Non-IDG -1.49520 31.8 212
T-complex protein 1 subunit delta CCT4 Tbio Non-IDG -1.77892 58.8 177
Homeobox-containing protein 1 HMBOX1 Tbio Transcription Factor -1.45982 30.3 138
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.66356 3766.3 513
H/ACA ribonucleoprotein complex non-core subunit NAF1 NAF1 Tbio Non-IDG 0.00000 27
cAMP-dependent protein kinase inhibitor beta PKIB Tbio Enzyme -0.86549 8.17 63