Development Level

Tchem 11 | 1,890
Tbio 5 | 10,625

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
decreased eosinophil cell numb... 2 | 41
abnormal embryo size 1 | 112
abnormal foot plate morphology 1 | 2
abnormal kidney morphology 1 | 30
abnormal testis morphology 1 | 30
craniofacial phenotype 1 | 9
decreased basophil cell number 1 | 11
decreased circulating creatini... 1 | 31
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased erythrocyte cell num... 1 | 26
male infertility 1 | 62
small testis 1 | 37

Disease

ovarian cancer 10 | 8,484
psoriasis 9 | 6,685
medulloblastoma, large-cell 8 | 6,234
osteosarcoma 8 | 7,933
Cancer 7 | 2,346
atypical teratoid / rhabdoid tumor 6 | 4,369
glioblastoma 5 | 5,572
Carcinoma 4 | 2,147
lung adenocarcinoma 4 | 2,713
lung cancer 4 | 4,466
primitive neuroectodermal tumor 4 | 3,031
Atopic dermatitis 3 | 944
Breast cancer 3 | 3,094
Lung Neoplasms 3 | 171
Stomach Neoplasms 3 | 282
Vascular disease 3 | 281
astrocytic glioma 3 | 2,241
breast carcinoma 3 | 1,614
group 3 medulloblastoma 3 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
malignant mesothelioma 3 | 3,162
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
Amyotrophic Lateral Sclerosis 2 | 431
Arthritis 2 | 248
Brain Ischemia 2 | 87
CEROID LIPOFUSCINOSIS, NEURONAL, 6 2 | 7
Cardiomyopathies 2 | 90
Cherubism 2 | 14
Cocaine-Related Disorders 2 | 88
Endometriosis 2 | 535
Female infertility 2 | 28
Gliosis 2 | 16
Head and Neck Neoplasms 2 | 23
Hyperalgesia 2 | 71
IGA Glomerulonephritis 2 | 454
Kidney Neoplasm 2 | 27
Malignant tumor of ovary 2 | 25
Neoplasm Invasiveness 2 | 127
Neoplasm Metastasis 2 | 138
Nerve Degeneration 2 | 73
Pick disease 2 | 1,893
Renal Cell Carcinoma 2 | 199
Rheumatoid Arthritis 2 | 1,160
Sepsis 2 | 21
Squamous cell carcinoma 2 | 94
Streptococcal pneumonia 2 | 6
Substance Withdrawal Syndrome 2 | 52
Toxic encephalopathy 2 | 131
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
dermatomyositis 2 | 933
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
invasive ductal carcinoma 2 | 2,950
lung carcinoma 2 | 2,844
non primary Sjogren syndrome sicca 2 | 840
ovarian neoplasm 2 | 97
pancreatic cancer 2 | 2,300
pediatric high grade glioma 2 | 2,712
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 789
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
ulcerative colitis 2 | 2,087
Acquired metabolic disease 1 | 267
Alzheimer's disease 1 | 644
Bladder Neoplasm 1 | 109
Down syndrome 1 | 548
Early infantile epileptic encephalopathy with suppression bursts 1 | 18
Endometrial Neoplasms 1 | 50
Epilepsy 1 | 346
Exanthem 1 | 39
Eye disease 1 | 55
Heart disease 1 | 279
Kidney disease 1 | 396
Lung disease 1 | 132
Mammary Neoplasms 1 | 410
Mammary Neoplasms, Experimental 1 | 150
Microcephaly 1 | 149
Multiple Sclerosis 1 | 498
Neurodegenerative disease 1 | 383
Parkinson's disease 1 | 364
Retinitis pigmentosa 1 | 153
Seizures 1 | 95
Sensorineural hearing loss 1 | 107
Weight Gain 1 | 87
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis 1 | 1,665
interstitial lung disease 1 | 291
medulloblastoma 1 | 1,524
nasopharyngeal carcinoma 1 | 1,056
pancreatic carcinoma 1 | 567
systemic lupus erythematosus 1 | 156
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 16 | 17,995
Cardiovascular System 16 | 17,958
Digestive Tract 16 | 18,473
Endocrine System 16 | 18,512
Female tissues 16 | 18,647
Liver and Pancreas 16 | 18,136
Male tissues 16 | 17,969
Nervous System 16 | 18,561
Respiratory system 16 | 17,484
Skin and soft tissues 16 | 18,115
Urinary Tract 16 | 18,444

Target Family

Kinase 10 | 634
Enzyme 5 | 4,146
Non-IDG 1 | 11,971

GO Process

positive regulation of telomer... 16 | 16
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase Nek2 NEK2 Tchem Kinase -2.11711 141.2 305
Regulator of telomere elongation helicase 1 RTEL1 Tbio Enzyme -2.35384 224.5 73
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.60410 3186.8 1232
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.83621 77.3 377
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.12872 1138.1 1044
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.68718 52.5 212
Mitogen-activated protein kinase kinase kinase 4 MAP3K4 Tbio Kinase -1.46056 29.2 232
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.60765 3454.0 459
Tankyrase-2 TNKS2 Tchem Enzyme -1.90827 81.1 142
Protein kinase C theta type PRKCQ Tchem Kinase -0.98992 9.41 554