Development Level

Tchem 11 | 1,388
Tbio 6 | 11,651

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal testis morphology 1 | 43
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
enlarged lymph nodes 1 | 37
increased bone mineral content 1 | 108
increased startle reflex 1 | 112
increased urine microalbumin l... 1 | 2
male infertility 1 | 123
small testis 1 | 58

Disease

ovarian cancer 11 | 8,520
Carcinoma 9 | 11,493
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Cancer 7 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
Breast cancer 4 | 3,578
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Lung Neoplasms 4 | 232
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Dull intelligence 3 | 645
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Neurodegenerative disease 3 | 414
Pick disease 3 | 1,894
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic lateral sclerosis 2 | 451
Arthritis 2 | 290
Brain Ischemia 2 | 110
CEROID LIPOFUSCINOSIS, NEURONAL, 6 2 | 6
Carcinoma, Squamous Cell 2 | 110
Cardiomyopathies 2 | 110
Cholestasis, Extrahepatic 2 | 25
Cocaine-Related Disorders 2 | 92
Cognitive delay 2 | 608
Dilated ventricles (finding) 2 | 121
Disease Models, Animal 2 | 155
Endometriosis 2 | 540
Female infertility 2 | 30
Fetal Growth Retardation 2 | 189
Gastrointestinal system disease 2 | 54
Gliosis 2 | 56
Global developmental delay 2 | 608
Head and Neck Neoplasms 2 | 26
Hyperalgesia 2 | 83
Hypertrophy 2 | 17
Infant, Small for Gestational Age 2 | 176
Infertility, Female 2 | 28
Intrauterine retardation 2 | 176
Kidney Neoplasm 2 | 29
Kidney Neoplasms 2 | 37
Liver Neoplasms, Experimental 2 | 59
Malignant tumor of ovary 2 | 25
Mental and motor retardation 2 | 608
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Nerve Degeneration 2 | 121
Obesity 2 | 678
Ovarian Neoplasms 2 | 102
Pneumonia, Pneumococcal 2 | 6
Radiation Injuries, Experimental 2 | 11
Renal Cell Carcinoma 2 | 214
Rheumatoid arthritis 2 | 1,191
Sepsis 2 | 24
Short stature 2 | 531
Small head 2 | 374
Squamous cell carcinoma 2 | 129
Streptococcal pneumonia 2 | 6
Substance Withdrawal Syndrome 2 | 55
Toxic encephalopathy 2 | 141
Trigeminal Neuralgia 2 | 24
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
ovarian neoplasm 2 | 99
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
Developmental Disabilities 1 | 23
Peripheral Neuropathy 1 | 134

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Kinase 10 | 634
Enzyme 5 | 4,145
Non-IDG 2 | 12,091

GO Process

positive regulation of telomer... 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.87360 78.8 436
Serine/threonine-protein kinase Nek2 NEK2 Tchem Kinase -2.10735 135.5 327
Tankyrase-2 TNKS2 Tchem Enzyme -1.95640 86.0 160
Dual specificity mitogen-activated protein kinase kinase 7 MAP2K7 Tchem Kinase -3.66356 3766.3 513
Mitogen-activated protein kinase kinase kinase 4 MAP3K4 Tbio Kinase -1.49704 31.8 244
Regulator of telomere elongation helicase 1 RTEL1 Tbio Enzyme -2.66156 233.0 85
Serine/threonine-protein kinase Nek7 NEK7 Tchem Kinase -1.31475 20.8 261