Development Level

Tbio 17 | 10,625
Tchem 11 | 1,890

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal bone mineralization 1 | 55
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 30
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased basophil cell number 1 | 11
decreased circulating creatini... 1 | 31
decreased eosinophil cell numb... 1 | 41
enlarged lymph nodes 1 | 27
increased bone mineral density 1 | 52
increased erythrocyte cell num... 1 | 26
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
small testis 1 | 37

Disease

ovarian cancer 21 | 8,484
psoriasis 16 | 6,685
lung cancer 13 | 4,466
medulloblastoma, large-cell 12 | 6,234
osteosarcoma 11 | 7,933
Cancer 10 | 2,346
lung adenocarcinoma 10 | 2,713
glioblastoma 9 | 5,572
non-small cell lung cancer 9 | 2,798
Breast cancer 8 | 3,094
group 3 medulloblastoma 8 | 2,254
oligodendroglioma 8 | 2,849
primitive neuroectodermal tumor 8 | 3,031
astrocytic glioma 7 | 2,241
atypical teratoid / rhabdoid tumor 7 | 4,369
ductal carcinoma in situ 7 | 1,745
invasive ductal carcinoma 7 | 2,950
malignant mesothelioma 7 | 3,162
breast carcinoma 6 | 1,614
ependymoma 6 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
Atopic dermatitis 5 | 944
Pick disease 5 | 1,893
adrenocortical carcinoma 5 | 1,427
dermatomyositis 5 | 933
lung carcinoma 5 | 2,844
pancreatic cancer 5 | 2,300
primary pancreatic ductal adenocarcinoma 5 | 1,271
tuberculosis 5 | 1,557
Carcinoma 4 | 2,147
Lung Neoplasms 4 | 171
Rheumatoid Arthritis 4 | 1,160
Stomach Neoplasms 4 | 282
Vascular disease 4 | 281
gastric carcinoma 4 | 832
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
nasopharyngeal carcinoma 4 | 1,056
pediatric high grade glioma 4 | 2,712
pilocytic astrocytoma 4 | 3,086
pituitary cancer 4 | 1,972
posterior fossa group B ependymoma 4 | 1,530
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 2,087
Alzheimer's disease 3 | 644
Down syndrome 3 | 548
Dyskeratosis congenita 3 | 24
Kidney disease 3 | 396
Multiple myeloma 3 | 1,327
Neoplasm Invasiveness 3 | 127
Nerve Degeneration 3 | 73
Prostatic Neoplasms 3 | 471
Waldenstrons macroglobulinemia 3 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
colon cancer 3 | 1,475
diabetes mellitus 3 | 1,663
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 557
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
medulloblastoma 3 | 1,524
ovarian neoplasm 3 | 97
Amyotrophic Lateral Sclerosis 2 | 431
Arthritis 2 | 248
Brain Ischemia 2 | 87
CEROID LIPOFUSCINOSIS, NEURONAL, 6 2 | 7
Cardiomyopathies 2 | 90
Cocaine-Related Disorders 2 | 88
Colorectal Cancer 2 | 47
Colorectal Neoplasms 2 | 217
Endometriosis 2 | 535
Eye disease 2 | 55
Female infertility 2 | 28
Heart disease 2 | 279
Hyperalgesia 2 | 71
IGA Glomerulonephritis 2 | 454
Intellectual disability 2 | 573
Juvenile arthritis 2 | 124
Kidney Neoplasm 2 | 27
Mammary Neoplasms 2 | 410
Melanoma 2 | 261
Microcephaly 2 | 149
Neoplasm Metastasis 2 | 138
Obesity 2 | 616
Osteoporosis 2 | 257
Parkinson's disease 2 | 364
Renal Cell Carcinoma 2 | 199
Squamous cell carcinoma 2 | 94
Substance Withdrawal Syndrome 2 | 52
Toxic encephalopathy 2 | 131
acute quadriplegic myopathy 2 | 1,157
adult high grade glioma 2 | 2,148
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
cutaneous lupus erythematosus 2 | 1,056
cystic fibrosis 2 | 1,665
juvenile dermatomyositis 2 | 1,189
primary Sjogren syndrome 2 | 789
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482
spina bifida 2 | 1,064

Tissue

Blood and immune system 28 | 17,995
Cardiovascular System 28 | 17,958
Digestive Tract 28 | 18,473
Endocrine System 28 | 18,512
Female tissues 28 | 18,647
Liver and Pancreas 28 | 18,136
Male tissues 28 | 17,969
Nervous System 28 | 18,561
Respiratory system 28 | 17,484
Skin and soft tissues 28 | 18,115
Urinary Tract 28 | 18,444

Target Family

Kinase 10 | 634
Non-IDG 10 | 11,971
Enzyme 5 | 4,146
Transcription Factor 3 | 1,400

GO Process

positive regulation of telomer... 28 | 28
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit delta CCT4 Tbio Non-IDG -1.76354 56.6 151
Serine/threonine-protein kinase Nek2 NEK2 Tchem Kinase -2.11711 141.2 305
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.60410 3186.8 1232
Telomerase Cajal body protein 1 WRAP53 Tbio Enzyme -1.47972 28.4 51
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.83621 77.3 377
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.24508 169.4 383
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.80598 682.6 630
Protection of telomeres protein 1 POT1 Tbio Non-IDG -1.77005 58.3 169
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.12872 1138.1 1044
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.68718 52.5 212