Development Level

Tbio 21 | 11,651
Tchem 13 | 1,388

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating fructosa... 1 | 13
increased grip strength 1 | 41
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased urine microalbumin l... 1 | 2
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

ovarian cancer 27 | 8,520
Carcinoma 23 | 11,493
psoriasis 18 | 6,694
lung cancer 17 | 4,740
medulloblastoma, large-cell 16 | 6,241
Cancer 15 | 2,499
osteosarcoma 14 | 7,950
group 3 medulloblastoma 13 | 4,104
Breast cancer 12 | 3,578
glioblastoma 12 | 5,792
lung adenocarcinoma 12 | 2,716
ependymoma 11 | 4,679
non-small cell lung cancer 11 | 2,890
atypical teratoid / rhabdoid tumor 10 | 5,112
primitive neuroectodermal tumor 10 | 3,035
invasive ductal carcinoma 9 | 2,951
oligodendroglioma 9 | 2,850
Multiple myeloma 8 | 1,332
breast carcinoma 8 | 1,638
malignant mesothelioma 8 | 3,232
Waldenstrons macroglobulinemia 7 | 765
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pancreatic cancer 7 | 2,398
Intellectual disability 6 | 1,016
Stomach Neoplasms 6 | 300
Vascular disease 6 | 319
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
Astrocytoma, Pilocytic 5 | 3,081
Atopic dermatitis 5 | 952
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Neoplasm Metastasis 5 | 168
Pick disease 5 | 1,894
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
Squamous cell carcinoma 5 | 129
adult high grade glioma 5 | 3,801
dermatomyositis 5 | 966
interstitial cystitis 5 | 2,312
nasopharyngeal carcinoma 5 | 1,058
subependymal giant cell astrocytoma 5 | 2,287
Autosomal recessive predisposition 4 | 1,442
Disease Models, Animal 4 | 155
Dyskeratosis congenita 4 | 24
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Liver Neoplasms, Experimental 4 | 59
Malabsorption 4 | 82
Neurodegenerative disease 4 | 414
Ovarian Neoplasms 4 | 102
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
Small head 4 | 374
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
ovarian neoplasm 4 | 99
pediatric high grade glioma 4 | 1,064
periodontitis 4 | 293
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Anemia 3 | 365
Blood Coagulation Disorders 3 | 42
Cellular immunodeficiency 3 | 17
Coagulation abnormalities 3 | 27
Dilated ventricles (finding) 3 | 121
Down syndrome 3 | 499
Eye disease 3 | 62
Hemoglobin low 3 | 124
Hemorrhagic Disorders 3 | 30
Increased fracture rate 3 | 53
Kidney disease 3 | 430
Neoplasm Invasiveness 3 | 161
Neutrophil abnormality 3 | 20
Osteoporosis 3 | 363
Recurrent respiratory infections 3 | 141
Sparse hair 3 | 59
Thin, sparse hair 3 | 59
Varying degree of multiple fractures 3 | 53
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
fibroadenoma 3 | 559
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 13 | 12,091
Kinase 10 | 634
Enzyme 7 | 4,145
Transcription Factor 4 | 1,400

GO Process

positive regulation of telomer... 34 | 34
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
Telomerase Cajal body protein 1 WRAP53 Tbio Enzyme -1.50893 31.5 58
Protection of telomeres protein 1 POT1 Tbio Non-IDG -1.81787 59.9 202
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058
MAP kinase-activated protein kinase 5 MAPKAPK5 Tchem Kinase -1.87360 78.8 436