Development Level

Tbio 34 | 11,445
Tchem 10 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 4 | 979
enlarged heart 3 | 210
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
decreased body weight 2 | 161
decreased circulating serum al... 2 | 82
increased neutrophil cell numb... 2 | 46
abnormal brain morphology 1 | 13
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
hydroencephaly 1 | 14
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased spleen weight 1 | 10
increased startle reflex 1 | 112
male infertility 1 | 123
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 35 | 11,493
ovarian cancer 32 | 8,520
Cancer 30 | 2,499
glioblastoma 26 | 5,792
atypical teratoid / rhabdoid tumor 23 | 5,112
psoriasis 23 | 6,694
osteosarcoma 22 | 7,950
medulloblastoma, large-cell 21 | 6,241
ependymoma 20 | 4,679
adult high grade glioma 19 | 3,801
Breast cancer 17 | 3,578
Astrocytoma, Pilocytic 16 | 3,081
invasive ductal carcinoma 16 | 2,951
group 3 medulloblastoma 14 | 4,104
malignant mesothelioma 14 | 3,232
interstitial cystitis 13 | 2,312
lung cancer 13 | 4,740
lung carcinoma 13 | 2,843
pancreatic cancer 13 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
lung adenocarcinoma 12 | 2,716
subependymal giant cell astrocytoma 12 | 2,287
astrocytic glioma 11 | 2,597
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
non-small cell lung cancer 11 | 2,890
primitive neuroectodermal tumor 11 | 3,035
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Hypertension 9 | 396
Kidney cancer 9 | 2,613
Pick disease 9 | 1,894
cystic fibrosis 9 | 1,696
oligodendroglioma 9 | 2,850
Depressive disorder 8 | 409
Hypertensive disease 8 | 292
Kidney disease 8 | 430
primary pancreatic ductal adenocarcinoma 8 | 1,109
tuberculosis 8 | 2,010
Liver Cirrhosis, Experimental 7 | 769
Obesity 7 | 678
ulcerative colitis 7 | 1,819
Bipolar Disorder 6 | 666
Colorectal Neoplasms 6 | 243
Mental Depression 6 | 333
Proteinuria 6 | 144
Pulmonary Fibrosis 6 | 106
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
cutaneous lupus erythematosus 6 | 1,057
group 4 medulloblastoma 6 | 1,855
pituitary cancer 6 | 1,972
Asthma 5 | 385
Breast Neoplasms 5 | 445
Carcinoma, Hepatocellular 5 | 228
Cerebrovascular disease 5 | 238
Coronary artery disease 5 | 268
Down syndrome 5 | 499
Intellectual disability 5 | 1,016
Liver Cirrhosis 5 | 181
Liver carcinoma 5 | 240
Mammary Neoplasms 5 | 425
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
Renal Cell Carcinoma 5 | 214
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
Adenocarcinoma 4 | 122
Alzheimer's disease 4 | 658
Aortic Valve Insufficiency 4 | 40
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
Byzanthine arch palate 4 | 194
Carcinoma, Renal Cell 4 | 124
Chest Pain 4 | 38
Chronic Lymphocytic Leukemia 4 | 262
Congenital diaphragmatic hernia 4 | 67
Craniofacial Abnormalities 4 | 151
Crohn's disease 4 | 321
Duchenne muscular dystrophy 4 | 601
Flatfoot 4 | 73
Heart disease 4 | 306
Heart failure 4 | 162
Increase in blood pressure 4 | 119
Neuropathy 4 | 261
Orbital separation excessive 4 | 244
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
acute quadriplegic myopathy 4 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
chronic rhinosinusitis 4 | 512
fibroadenoma 4 | 559
medulloblastoma 4 | 720
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074

Tissue

Blood and immune system 48 | 16,909
Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Nervous System 47 | 16,725
Cardiovascular System 45 | 15,192

Target Family

Non-IDG 31 | 12,091
Kinase 7 | 634
Enzyme 6 | 4,145
GPCR 3 | 408
Transcription Factor 1 | 1,400

GO Process

positive regulation of stress ... 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
FH1/FH2 domain-containing protein 1 FHOD1 Tbio Non-IDG -1.49217 38.9 120
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Rho guanine nucleotide exchange factor 5 ARHGEF5 Tbio Non-IDG -0.48804 5.75 249
Rho guanine nucleotide exchange factor 15 ARHGEF15 Tbio Non-IDG -0.90240 8.54 26
SH3 and PX domain-containing protein 2B SH3PXD2B Tbio Non-IDG -1.72872 53.3 71
Psychosine receptor GPR65 Tbio GPCR -1.53268 38.5 173
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Protein S100-A10 S100A10 Tbio Non-IDG -2.26116 191.4 354
Profilin-1 PFN1 Tbio Non-IDG -2.31736 223.5 260