Development Level

Tbio 24 | 11,445
Tchem 20 | 1,598
Tclin 13 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

enlarged heart 5 | 210
preweaning lethality, complete... 5 | 979
decreased vertical activity 4 | 208
decreased blood urea nitrogen ... 3 | 51
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased circulating insulin ... 2 | 76
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to t... 2 | 278
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal skin morphology 1 | 50
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating triglyce... 1 | 79
decreased heart rate variabili... 1 | 13
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydroencephaly 1 | 14
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating triglyce... 1 | 42
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
stereotypic behavior 1 | 3
tremors 1 | 39
trunk curl 1 | 16

Disease

Cancer 46 | 2,499
Carcinoma 36 | 11,493
lung cancer 34 | 4,740
osteosarcoma 32 | 7,950
ovarian cancer 32 | 8,520
psoriasis 32 | 6,694
malignant mesothelioma 30 | 3,232
glioblastoma 29 | 5,792
non-small cell lung cancer 26 | 2,890
medulloblastoma, large-cell 25 | 6,241
interstitial cystitis 23 | 2,312
diabetes mellitus 22 | 1,728
lung carcinoma 22 | 2,843
Breast cancer 21 | 3,578
invasive ductal carcinoma 21 | 2,951
atypical teratoid / rhabdoid tumor 20 | 5,112
tuberculosis 20 | 2,010
cystic fibrosis 19 | 1,696
Hypertension 18 | 396
Obesity 18 | 678
lung adenocarcinoma 18 | 2,716
Coronary artery disease 17 | 268
Kidney disease 17 | 430
Schizophrenia 17 | 1,160
pancreatic cancer 17 | 2,398
ulcerative colitis 17 | 1,819
Atherosclerosis 16 | 291
Liver Cirrhosis, Experimental 16 | 769
Rheumatoid arthritis 16 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
Arthritis 14 | 290
Asthma 14 | 385
Depressive disorder 14 | 409
Hypertensive disease 14 | 292
Vascular disease 14 | 319
Astrocytoma, Pilocytic 13 | 3,081
Breast Neoplasms 13 | 445
Lung disease 13 | 142
Mammary Neoplasms 13 | 425
adult high grade glioma 13 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Alzheimer's disease 12 | 658
Cerebrovascular disease 12 | 238
Hyperglycemia 12 | 137
breast carcinoma 12 | 1,638
cutaneous lupus erythematosus 12 | 1,057
group 3 medulloblastoma 12 | 4,104
pituitary cancer 12 | 1,972
Arthritis, Rheumatoid 11 | 174
Carcinoma, Hepatocellular 11 | 228
Liver carcinoma 11 | 240
Lung Neoplasms 11 | 232
Prostatic Neoplasms 11 | 495
acute quadriplegic myopathy 11 | 1,158
adrenocortical carcinoma 11 | 1,428
ependymoma 11 | 4,679
mucosa-associated lymphoid tissue lymphoma 11 | 484
Autosomal recessive predisposition 10 | 1,442
Endometriosis 10 | 540
Kidney cancer 10 | 2,613
Mental Depression 10 | 333
Stomach Neoplasms 10 | 300
colon cancer 10 | 1,478
ductal carcinoma in situ 10 | 1,745
group 4 medulloblastoma 10 | 1,855
primitive neuroectodermal tumor 10 | 3,035
subependymal giant cell astrocytoma 10 | 2,287
Anemia 9 | 365
Bipolar Disorder 9 | 666
Diarrhea 9 | 253
Heart disease 9 | 306
Inflammatory bowel disease 9 | 151
Kidney Failure, Chronic 9 | 46
Liver disease 9 | 237
Neoplasm Metastasis 9 | 168
Parkinson's disease 9 | 392
Renal Cell Carcinoma 9 | 214
Seizures 9 | 596
acute myeloid leukemia 9 | 783
oligodendroglioma 9 | 2,850
Brain disease 8 | 96
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Epilepsy 8 | 792
Heart failure 8 | 162
Hyperalgesia 8 | 83
Hypersensitivity reaction type II disease 8 | 253
Hypoplastic mandible condyle 8 | 275
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Multiple Sclerosis 8 | 540
Osteoporosis 8 | 363
Reperfusion Injury 8 | 86
Toxic encephalopathy 8 | 141
active ulcerative colitis 8 | 764
gastric cancer 8 | 459
gastric carcinoma 8 | 807
hepatocellular carcinoma 8 | 547
pediatric high grade glioma 8 | 1,064

Tissue

Blood and immune system 57 | 16,909
Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Liver and Pancreas 57 | 16,750
Respiratory system 57 | 16,393
Skin and soft tissues 57 | 17,230
Urinary Tract 57 | 16,678
Female tissues 56 | 17,400
Male tissues 56 | 17,142
Nervous System 55 | 16,725
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 11 | 4,145
Kinase 9 | 634
Transcription Factor 6 | 1,400
GPCR 4 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

positive regulation of smooth ... 57 | 57
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Multidrug resistance-associated protein 4 ABCC4 Tchem Transporter -2.56001 341.6 352
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
RNA-binding protein with multiple splicing 2 RBPMS2 Tbio Non-IDG -0.50060 3.69 81
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134
Neutrophil elastase ELANE Tclin Enzyme -3.61753 3958.4 411
Forkhead box protein P1 FOXP1 Tbio Transcription Factor -2.32310 210.5 533
Transcriptional activator Myb MYB Tbio Transcription Factor -2.97697 938.9 642
Ribosomal protein S6 kinase beta-1 RPS6KB1 Tchem Kinase -3.18361 0.00000 1818
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289