Development Level

Tbio 82 | 11,445
Tchem 14 | 1,598
Tclin 12 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased vertical activity 5 | 208
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
increased total body fat amoun... 4 | 134
decreased lean body mass 3 | 135
embryonic lethality prior to t... 3 | 278
decreased heart left ventricle... 2 | 28
decreased mean platelet volume 2 | 25
decreased neutrophil cell numb... 2 | 42
female infertility 2 | 60
increased hemoglobin content 2 | 45
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
thin ventricular wall 2 | 24
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal ovary morphology 1 | 7
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent epididymis 1 | 3
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hydroencephaly 1 | 14
hydrops fetalis 1 | 1
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
microphthalmia 1 | 26
premature death 1 | 5
prenatal lethality 1 | 28
scaly skin 1 | 4
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small uterus 1 | 3

Disease

Carcinoma 72 | 11,493
ovarian cancer 58 | 8,520
osteosarcoma 55 | 7,950
psoriasis 54 | 6,694
Cancer 51 | 2,499
lung cancer 45 | 4,740
glioblastoma 44 | 5,792
medulloblastoma, large-cell 40 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
ependymoma 34 | 4,679
malignant mesothelioma 33 | 3,232
group 3 medulloblastoma 31 | 4,104
Breast cancer 30 | 3,578
adult high grade glioma 30 | 3,801
Astrocytoma, Pilocytic 28 | 3,081
tuberculosis 27 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
subependymal giant cell astrocytoma 25 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
invasive ductal carcinoma 22 | 2,951
Obesity 21 | 678
lung carcinoma 21 | 2,843
Schizophrenia 20 | 1,160
lung adenocarcinoma 20 | 2,716
oligodendroglioma 20 | 2,850
pancreatic cancer 20 | 2,398
primitive neuroectodermal tumor 20 | 3,035
diabetes mellitus 19 | 1,728
non-small cell lung cancer 19 | 2,890
pituitary cancer 19 | 1,972
Osteoporosis 18 | 363
astrocytic glioma 18 | 2,597
ulcerative colitis 18 | 1,819
Rheumatoid arthritis 17 | 1,191
Autosomal recessive predisposition 16 | 1,442
cystic fibrosis 16 | 1,696
Kidney cancer 15 | 2,613
Prostatic Neoplasms 15 | 495
breast carcinoma 15 | 1,638
juvenile dermatomyositis 15 | 1,187
Breast Neoplasms 14 | 445
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mammary Neoplasms 14 | 425
Mental and motor retardation 14 | 608
Multiple myeloma 14 | 1,332
colon cancer 14 | 1,478
ductal carcinoma in situ 14 | 1,745
Dull intelligence 13 | 645
Intellectual disability 13 | 1,016
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
group 4 medulloblastoma 13 | 1,855
interstitial cystitis 13 | 2,312
Alzheimer's disease 12 | 658
Arthritis 12 | 290
Parkinson's disease 12 | 392
Waldenstrons macroglobulinemia 12 | 765
adrenocortical carcinoma 12 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Asthma 11 | 385
Heart disease 11 | 306
Hyperglycemia 11 | 137
Pick disease 11 | 1,894
Seizures 11 | 596
cutaneous lupus erythematosus 11 | 1,057
Anemia 10 | 365
Bipolar Disorder 10 | 666
Carcinoma, Hepatocellular 10 | 228
Influenza 10 | 142
Liver carcinoma 10 | 240
Major Depressive Disorder 10 | 301
Myocardial Infarction 10 | 151
Short stature 10 | 531
Atopic dermatitis 9 | 952
Brain disease 9 | 96
Coronary artery disease 9 | 268
Epilepsy 9 | 792
Inflammatory bowel disease 9 | 151
Kidney disease 9 | 430
Lung Neoplasms 9 | 232
Lung disease 9 | 142
Lymphoid leukemia 9 | 160
Melanoma 9 | 711
Mental Depression 9 | 333
Multiple Sclerosis 9 | 540
Muscle hypotonia 9 | 571
Stomach Neoplasms 9 | 300
Unipolar Depression 9 | 250
Vascular disease 9 | 319
dermatomyositis 9 | 966
sonic hedgehog group medulloblastoma 9 | 467
spina bifida 9 | 1,074
Depressive disorder 8 | 409
Endometriosis 8 | 540
Hypereosinophilic syndrome 8 | 71
periodontitis 8 | 293

Tissue

Digestive Tract 104 | 17,369
Endocrine System 102 | 18,159
Female tissues 102 | 17,400
Nervous System 101 | 16,725
Skin and soft tissues 101 | 17,230
Liver and Pancreas 100 | 16,750
Urinary Tract 99 | 16,678
Male tissues 97 | 17,142
Blood and immune system 96 | 16,909
Respiratory system 96 | 16,393
Cardiovascular System 91 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 18 | 4,145
Transcription Factor 17 | 1,400
Kinase 8 | 634
Epigenetic 6 | 242
GPCR 3 | 408
Nuclear Receptor 3 | 48
TF/Epigenetic 1 | 38

GO Process

positive regulation of sequenc... 108 | 108
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Probable E3 ubiquitin-protein ligase MID2 MID2 Tbio Enzyme -2.49198 303.4 152
Protein BEX1 BEX1 Tbio Non-IDG -1.32314 23.8 124
Junction-mediating and -regulatory protein JMY Tbio Non-IDG -1.26760 21.2 162
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Tripartite motif-containing protein 26 TRIM26 Tbio Non-IDG -0.84838 7.42 107
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Rho guanine nucleotide exchange factor 5 ARHGEF5 Tbio Non-IDG -0.48804 5.75 249
Tripartite motif-containing protein 34 TRIM34 Tbio Non-IDG -1.20185 9.98 78
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25892 1754.8 177