Development Level

Tbio 21 | 11,651
Tchem 8 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
hyperactivity 2 | 148
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
abnormal coat- hair morphology 1 | 19
abnormal lens morphology 1 | 81
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hypoactivity 1 | 132
increased IgG2b level 1 | 1
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Cancer 17 | 2,499
ovarian cancer 16 | 8,520
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
lung cancer 14 | 4,740
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 13 | 7,950
adult high grade glioma 12 | 3,801
malignant mesothelioma 12 | 3,232
pancreatic cancer 12 | 2,398
psoriasis 12 | 6,694
ependymoma 10 | 4,679
Carcinoma 9 | 11,493
group 3 medulloblastoma 9 | 4,104
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
ductal carcinoma in situ 8 | 1,745
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
Prostatic Neoplasms 7 | 495
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
Schizophrenia 6 | 1,160
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
esophageal adenocarcinoma 6 | 737
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Alzheimer's disease 5 | 658
Breast Neoplasms 5 | 445
Breast cancer 5 | 3,578
Carcinoma, Hepatocellular 5 | 228
Colonic Neoplasms 5 | 142
Liver carcinoma 5 | 240
Mammary Neoplasms 5 | 425
Vascular disease 5 | 319
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
hepatocellular carcinoma 5 | 547
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Bipolar Disorder 4 | 666
Endometriosis 4 | 540
Multiple myeloma 4 | 1,332
Neoplasm Metastasis 4 | 168
Nerve Degeneration 4 | 121
Pick disease 4 | 1,894
Stomach Neoplasms 4 | 300
cutaneous lupus erythematosus 4 | 1,057
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
mucosa-associated lymphoid tissue lymphoma 4 | 484
spina bifida 4 | 1,074
Autosomal recessive predisposition 3 | 1,442
Brain Ischemia 3 | 110
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Squamous Cell 3 | 110
Chronic Lymphocytic Leukemia 3 | 262
Colorectal Neoplasms 3 | 243
Diabetes Mellitus, Experimental 3 | 108
Esophageal Neoplasms 3 | 69
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Leukemia 3 | 104
Leukemia, Lymphocytic, Chronic, B-Cell 3 | 34
Liver Cirrhosis, Experimental 3 | 769
Liver Neoplasms, Experimental 3 | 59
Myocardial Infarction 3 | 151
Neurodegenerative disease 3 | 414
Optic Atrophy 3 | 242
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Parkinson's disease 3 | 392
Squamous cell carcinoma 3 | 129
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
fibroadenoma 3 | 559
gastric cancer 3 | 459
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
Atopic dermatitis 2 | 952
Epilepsy 2 | 792
Infertility, Male 2 | 46
Male infertility 2 | 206
Polycystic ovary syndrome 2 | 360
aldosterone-producing adenoma 2 | 665
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333

Tissue

Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Cardiovascular System 28 | 15,192
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Urinary Tract 28 | 16,678

Target Family

Non-IDG 23 | 12,091
Enzyme 4 | 4,145
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of release... 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Apoptosis-associated speck-like protein containing a CARD PYCARD Tbio Non-IDG -1.86744 55.9 477
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
Bcl-2-like protein 11 BCL2L11 Tbio Non-IDG -3.18092 1465.8 931
Cell death activator CIDE-B CIDEB Tbio Non-IDG -1.29216 23.6 249
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 Tbio Non-IDG -2.51675 340.9 331