Development Level

Tbio 14 | 11,651
Tchem 13 | 1,388
Tclin 4 | 612

IMPC Phenotype

enlarged heart 3 | 210
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
decreased circulating insulin ... 2 | 76
preweaning lethality, complete... 2 | 979
abnormal epididymis morphology 1 | 42
abnormal liver morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased bone mineral content 1 | 108
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small testis 1 | 58
tremors 1 | 39

Disease

Cancer 21 | 2,499
Carcinoma 19 | 11,493
psoriasis 17 | 6,694
osteosarcoma 16 | 7,950
ovarian cancer 16 | 8,520
glioblastoma 15 | 5,792
lung cancer 14 | 4,740
malignant mesothelioma 12 | 3,232
medulloblastoma, large-cell 11 | 6,241
pancreatic cancer 11 | 2,398
Kidney disease 10 | 430
Liver Cirrhosis, Experimental 10 | 769
Schizophrenia 10 | 1,160
atypical teratoid / rhabdoid tumor 10 | 5,112
Astrocytoma, Pilocytic 9 | 3,081
Cerebrovascular disease 9 | 238
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
Hypertension 8 | 396
non-small cell lung cancer 8 | 2,890
Atherosclerosis 7 | 291
Breast cancer 7 | 3,578
Prostatic Neoplasms 7 | 495
adult high grade glioma 7 | 3,801
ductal carcinoma in situ 7 | 1,745
ependymoma 7 | 4,679
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Coronary artery disease 6 | 268
Hypertensive disease 6 | 292
Obesity 6 | 678
Seizures 6 | 596
adrenocortical carcinoma 6 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
breast carcinoma 6 | 1,638
interstitial cystitis 6 | 2,312
nephrosclerosis 6 | 333
primary pancreatic ductal adenocarcinoma 6 | 1,109
Bipolar Disorder 5 | 666
Colonic Neoplasms 5 | 142
Depressive disorder 5 | 409
Heart disease 5 | 306
Heart failure 5 | 162
Hyperglycemia 5 | 137
Lung Neoplasms 5 | 232
Thrombocytopenia 5 | 197
Vascular disease 5 | 319
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
gastric carcinoma 5 | 807
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pituitary cancer 5 | 1,972
Alcoholic Intoxication, Chronic 4 | 289
Amyotrophic lateral sclerosis 4 | 451
Brain disease 4 | 96
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Chemical and Drug Induced Liver Injury 4 | 195
Cholestasis 4 | 155
Diabetic Nephropathies 4 | 37
Diabetic Nephropathy 4 | 34
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Fatty Liver 4 | 70
Kidney Diseases 4 | 114
Liver Cirrhosis 4 | 181
Liver carcinoma 4 | 240
Lung disease 4 | 142
Mammary Neoplasms 4 | 425
Polycystic ovary syndrome 4 | 360
Psychotic Disorders 4 | 151
Pulmonary Fibrosis 4 | 106
Reperfusion Injury 4 | 86
Rheumatoid arthritis 4 | 1,191
Skin Neoplasms 4 | 69
Small head 4 | 374
Stomach Neoplasms 4 | 300
Toxic encephalopathy 4 | 141
dermatomyositis 4 | 966
juvenile dermatomyositis 4 | 1,187
limb girdle muscular dystrophy 2A 4 | 213
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Chronic obstructive pulmonary disease 3 | 184
Endometriosis 3 | 540
Waldenstrons macroglobulinemia 3 | 765
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
fibroadenoma 3 | 559
hepatocellular carcinoma 3 | 547
nasopharyngeal carcinoma 3 | 1,058

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Blood and immune system 29 | 16,909
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Female tissues 28 | 17,400
Respiratory system 28 | 16,393
Nervous System 27 | 16,725
Cardiovascular System 26 | 15,192

Target Family

Enzyme 12 | 4,145
Non-IDG 11 | 12,091
Kinase 5 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

positive regulation of reactiv... 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
NADPH oxidase 5 NOX5 Tbio Enzyme -1.82693 76.8 174
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Receptor-interacting serine/threonine-protein kinase 3 RIPK3 Tchem Kinase -2.22748 161.7 603
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509