Development Level

Tbio 59 | 10,625
Tdark 13 | 7,003
Tchem 11 | 1,890
Tclin 2 | 602

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

decreased total body fat amoun... 5 | 186
increased bone mineral content 4 | 92
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
decreased circulating glucose ... 2 | 121
decreased erythrocyte cell num... 2 | 43
decreased grip strength 2 | 123
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
embryonic lethality prior to t... 2 | 187
increased blood urea nitrogen ... 2 | 44
increased circulating alkaline... 2 | 119
increased effector memory CD4-... 2 | 15
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased monocyte cell number 2 | 27
increased or absent threshold ... 2 | 128
short tibia 2 | 82
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal ear morphology 1 | 5
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal locomotor activation 1 | 26
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placement of pupils 1 | 4
abnormal response to tactile s... 1 | 16
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal spinal cord morpholog... 1 | 8
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
circling 1 | 1
decreased B cell number 1 | 30
decreased CD8-positive, alpha-... 1 | 26
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased T-helper cell number 1 | 4
decreased alpha-beta T cell nu... 1 | 12
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating glycerol... 1 | 19
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
head bobbing 1 | 3
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1-positive CD4-p... 1 | 3
increased Ly6C low monocyte nu... 1 | 8
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating chloride... 1 | 43
increased effector memory CD8-... 1 | 14
increased fluid intake 1 | 1
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34
trunk curl 1 | 15
vertebral transformation 1 | 12

Disease

ovarian cancer 47 | 8,484
osteosarcoma 39 | 7,933
glioblastoma 32 | 5,572
psoriasis 30 | 6,685
medulloblastoma, large-cell 28 | 6,234
lung cancer 23 | 4,466
atypical teratoid / rhabdoid tumor 22 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
pilocytic astrocytoma 18 | 3,086
pediatric high grade glioma 17 | 2,712
astrocytic glioma 15 | 2,241
malignant mesothelioma 15 | 3,162
oligodendroglioma 15 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
primitive neuroectodermal tumor 14 | 3,031
Cancer 13 | 2,346
diabetes mellitus 13 | 1,663
invasive ductal carcinoma 13 | 2,950
subependymal giant cell astrocytoma 13 | 2,287
Breast cancer 12 | 3,094
interstitial cystitis 12 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
lung adenocarcinoma 12 | 2,713
lung carcinoma 12 | 2,844
non-small cell lung cancer 12 | 2,798
Multiple myeloma 11 | 1,327
adult high grade glioma 11 | 2,148
ductal carcinoma in situ 11 | 1,745
ependymoma 11 | 2,514
group 3 medulloblastoma 11 | 2,254
medulloblastoma 10 | 1,524
pancreatic cancer 10 | 2,300
Pick disease 9 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
posterior fossa group A ependymoma 9 | 1,511
posterior fossa group B ependymoma 9 | 1,530
breast carcinoma 8 | 1,614
pituitary cancer 8 | 1,972
sonic hedgehog group medulloblastoma 8 | 1,482
Carcinoma 7 | 2,147
acute quadriplegic myopathy 7 | 1,157
colon cancer 7 | 1,475
cystic fibrosis 7 | 1,665
tuberculosis 7 | 1,557
ulcerative colitis 7 | 2,087
Schizophrenia 6 | 501
cutaneous lupus erythematosus 6 | 1,056
esophageal adenocarcinoma 6 | 737
group 4 medulloblastoma 6 | 1,875
tuberculosis and treatment for 6 months 6 | 686
Asthma 5 | 349
Bipolar Disorder 5 | 266
Down syndrome 5 | 548
Rheumatoid Arthritis 5 | 1,160
adrenocortical carcinoma 5 | 1,427
aldosterone-producing adenoma 5 | 664
astrocytoma 5 | 1,493
atypical teratoid/rhabdoid tumor 5 | 1,095
hepatocellular carcinoma 5 | 532
mucosa-associated lymphoid tissue lymphoma 5 | 480
nasopharyngeal carcinoma 5 | 1,056
spina bifida 5 | 1,064
Atopic dermatitis 4 | 944
IGA Glomerulonephritis 4 | 454
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
juvenile dermatomyositis 4 | 1,189
periodontitis 4 | 269
primary pancreatic ductal adenocarcinoma 4 | 1,271
Alzheimer's disease 3 | 644
Duchenne muscular dystrophy 3 | 602
Intellectual disability 3 | 573
Mammary Neoplasms 3 | 410
Multiple Sclerosis 3 | 498
Obesity 3 | 616
Osteoporosis 3 | 257
Parkinson's disease 3 | 364
gastric cancer 3 | 430
gastric carcinoma 3 | 832
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
primary Sjogren syndrome 3 | 789
progressive supranuclear palsy 3 | 674
Allergic hypersensitivity disease 2 | 123
Atherosclerosis 2 | 275
Crohn's disease 2 | 304
Dermatitis 2 | 107
Disease Progression 2 | 125
Eosinophilia 2 | 65
Heart disease 2 | 279
Metabolic syndrome X 2 | 155
Peripheral Neuropathy 2 | 303
Polycystic Ovary Syndrome 2 | 332
Stomach Neoplasms 2 | 282
active Crohn's disease 2 | 918
dermatomyositis 2 | 933
fibroadenoma 2 | 557
type II diabetes mellitus and post-ischemic heart failure 2 | 89
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 85 | 18,473
Endocrine System 85 | 18,512
Female tissues 85 | 18,647
Liver and Pancreas 85 | 18,136
Nervous System 85 | 18,561
Blood and immune system 84 | 17,995
Cardiovascular System 84 | 17,958
Skin and soft tissues 84 | 18,115
Male tissues 83 | 17,969
Respiratory system 83 | 17,484
Urinary Tract 83 | 18,444

Target Family

Non-IDG 42 | 11,971
Enzyme 25 | 4,146
Transcription Factor 5 | 1,400
GPCR 4 | 406
Kinase 4 | 634
Epigenetic 2 | 242
Ion Channel 1 | 341
Transporter 1 | 473
oGPCR 1 | 421

GO Process

positive regulation of protein... 85 | 85
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DTW domain-containing protein 2 DTWD2 Tdark Non-IDG 0.34 0.44 46
Protein Mis18-alpha MIS18A Tdark Non-IDG -2.10690 101.0 41
G-protein coupled receptor 26 GPR26 Tbio GPCR -0.57545 4.04 88
WD repeat-containing protein 75 WDR75 Tdark Non-IDG -0.40457 2.42 13
Interferon lambda-3 IFNL3 Tbio Non-IDG -3.04964 1189.7 153
Olfactory receptor 13C4 OR13C4 Tdark oGPCR -0.17609 1.50 29
26S proteasome non-ATPase regulatory subunit 8 PSMD8 Tbio Enzyme -1.35900 20.6 94
Leptin receptor gene-related protein LEPROT Tbio Non-IDG -0.98415 11.6 2
Putative ATP-dependent RNA helicase TDRD12 TDRD12 Tdark Epigenetic -0.68009 4.78 17
Glycogen synthase kinase-3 alpha GSK3A Tclin Kinase -1.81647 52.3 722