Development Level

Tbio 63 | 11,445
Tchem 10 | 1,598
Tdark 10 | 6,588
Tclin 2 | 613

Collection

RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased prepulse inhibition 3 | 82
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased bone mineral content 3 | 108
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
decreased body length 2 | 101
decreased circulating triglyce... 2 | 79
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased blood urea nitrogen ... 2 | 48
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal response to tactile s... 1 | 17
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating lactate ... 1 | 3
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
head bobbing 1 | 5
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased caudal vertebrae num... 1 | 7
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating insulin ... 1 | 3
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
mammalian phenotype 1 | 17
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
thick skin 1 | 4
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 54 | 11,493
ovarian cancer 47 | 8,520
osteosarcoma 39 | 7,950
glioblastoma 32 | 5,792
psoriasis 30 | 6,694
medulloblastoma, large-cell 28 | 6,241
ependymoma 25 | 4,679
lung cancer 25 | 4,740
atypical teratoid / rhabdoid tumor 24 | 5,112
adult high grade glioma 23 | 3,801
group 3 medulloblastoma 23 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
Astrocytoma, Pilocytic 18 | 3,081
malignant mesothelioma 16 | 3,232
astrocytic glioma 15 | 2,597
oligodendroglioma 15 | 2,850
Schizophrenia 14 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
primitive neuroectodermal tumor 14 | 3,035
Breast cancer 13 | 3,578
Cancer 13 | 2,499
diabetes mellitus 13 | 1,728
invasive ductal carcinoma 13 | 2,951
lung adenocarcinoma 13 | 2,716
subependymal giant cell astrocytoma 13 | 2,287
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
lung carcinoma 12 | 2,843
non-small cell lung cancer 12 | 2,890
Multiple myeloma 11 | 1,332
ductal carcinoma in situ 11 | 1,745
pancreatic cancer 11 | 2,398
Pick disease 9 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
tuberculosis 9 | 2,010
Kidney cancer 8 | 2,613
breast carcinoma 8 | 1,638
pituitary cancer 8 | 1,972
acute quadriplegic myopathy 7 | 1,158
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
Asthma 6 | 385
Bipolar Disorder 6 | 666
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
esophageal adenocarcinoma 6 | 737
group 4 medulloblastoma 6 | 1,855
ulcerative colitis 6 | 1,819
Liver Cirrhosis, Experimental 5 | 769
Rheumatoid arthritis 5 | 1,191
aldosterone-producing adenoma 5 | 665
astrocytoma 5 | 1,146
hepatocellular carcinoma 5 | 547
mucosa-associated lymphoid tissue lymphoma 5 | 484
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Atopic dermatitis 4 | 952
Breast Neoplasms 4 | 445
Down syndrome 4 | 499
Intellectual disability 4 | 1,016
Mammary Neoplasms 4 | 425
Obesity 4 | 678
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
periodontitis 4 | 293
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis and treatment for 6 months 4 | 409
Alzheimer's disease 3 | 658
Autosomal recessive predisposition 3 | 1,442
Disease Progression 3 | 136
Duchenne muscular dystrophy 3 | 601
Lung Neoplasms 3 | 232
Major Depressive Disorder 3 | 301
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Osteoporosis 3 | 363
Parkinson's disease 3 | 392
Stomach Neoplasms 3 | 300
Unipolar Depression 3 | 250
active ulcerative colitis 3 | 764
atypical teratoid/rhabdoid tumor 3 | 357
gastric cancer 3 | 459
gastric carcinoma 3 | 807
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
progressive supranuclear palsy 3 | 676
Allergic hypersensitivity disease 2 | 126
Depressive disorder 2 | 409
Epilepsy 2 | 792
Hypereosinophilic syndrome 2 | 71
Polycystic ovary syndrome 2 | 360
dermatomyositis 2 | 966
fibroadenoma 2 | 559
sonic hedgehog group medulloblastoma 2 | 467
urothelial carcinoma 2 | 318

Tissue

Endocrine System 84 | 18,159
Female tissues 81 | 17,400
Skin and soft tissues 81 | 17,230
Digestive Tract 80 | 17,369
Blood and immune system 79 | 16,909
Liver and Pancreas 79 | 16,750
Male tissues 79 | 17,142
Nervous System 78 | 16,725
Urinary Tract 78 | 16,678
Respiratory system 77 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 25 | 4,145
Transcription Factor 5 | 1,400
GPCR 4 | 408
Kinase 4 | 634
Epigenetic 2 | 242
Ion Channel 1 | 344
Transporter 1 | 473
oGPCR 1 | 421

GO Process

positive regulation of protein... 85 | 85
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable palmitoyltransferase ZDHHC8 ZDHHC8 Tbio Enzyme -1.30633 19.3 116
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
NADH-cytochrome b5 reductase 1 CYB5R1 Tbio Enzyme -0.95573 7.22 142
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
Protein OSCP1 OSCP1 Tbio Non-IDG -1.26403 22.2 47
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Zinc finger protein PLAGL2 PLAGL2 Tbio Transcription Factor -1.60659 35.2 61
Solute carrier family 17 member 9 SLC17A9 Tchem Transporter -1.56271 40.4 11
Histamine N-methyltransferase HNMT Tchem Enzyme -2.88300 757.5 234
Sterol regulatory element-binding protein 2 SREBF2 Tchem Transcription Factor -2.61148 361.0 205